Results 231 to 240 of about 70,546 (390)

Synthesis of Rhamnose‐Modified Lewis‐X‐Containing Saponins

European Journal of Organic Chemistry, Accepted Article.
We report the synthesis of betulinic acid and echinocystic acid saponins featuring an unnatural analogue of the Lewis‐X trisaccharide, in which the l‐fucose residue is replaced by l‐rhamnose. These triterpenoid saponins were designed as negative controls for dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing non‐integrin (DC‐SIGN ...
Oscar Javier Gamboa Marin, Nitish Verma, Maude Cloutier, Charles Gauthier   +3 more
wiley   +1 more source

Editorial: Recent advances in synthesizing and utilizing nitrogen-containing heterocycles

Frontiers in Chemistry
Takashi Ohshima, Hsyueh-Liang Wu, Hyun-Joon Ha   +2 more
doaj   +1 more source

Discovery of Sphingosine Kinase Inhibition by Modified Quinoline-5,8-Diones. [PDF]

Pharmaceuticals (Basel)
Kruschel RD, Malone K, Walsh AN, Waeber C, McCarthy FO.   +4 more
europepmc   +1 more source

Mass Spectra of Bis-Amide Pyrrolidine Alkaloids.

, 1994
Naoto Senda, Hisamasa WAKAYAMA, Tomoyuki Fujita, Tomomi Bando, Kenichi Shizukuishi, H. Yamaoka, Mitsuru Nakayama   +6 more
openalex   +2 more sources

Synthesis of Substituted Pyrrolidines

, 2016
The task of medicinal chemists in a drug discoveryproject is to synthesize/design analogues to the screening hits, simultaneouslyincreasing target potency and optimizing the pharmacological properties.  This requires a wide selection of moleculesto be synthesized, where both synthetic feasibility and price of startingmaterials are of great importance ...
openaire   +1 more source

Green‐light Cerium Photocatalysis enabled by Pyridine N‐oxide Ligands

European Journal of Organic Chemistry, Accepted Article.
Abstract: We report pyridine N‐oxides as neutral ligands in cerium photocatalysis. By using those neutral ligands, photoactive Ce(IV)‐species are generated, that show an extensive bathochromic shift compared to previously employed cerium‐based complexes. This allows the effective utilization of green light in the redox‐neutral CH‐hydrazination of small
Nicolas Müller, Jessica Stahl, Julia Stoiber, Burkhard König   +3 more
wiley   +1 more source

Pyrrolidine derivatives as α-amylase and α-glucosidase inhibitors: Design, synthesis, structure-activity relationship (SAR), docking studies and HSA binding. [PDF]

Heliyon
Bhat AA, Tandon N, Singh I.
europepmc   +1 more source

Studies on the Constituents of Broussonetia Species. II. Six New Pyrrolidine Alkaloids, Broussonetine A, B, E, F and Broussonetinine A and B, as Inhibitors of Glycosidases from Broussonetia kazinoki SIEB.

, 1997
Makio Shibano, Satoshi KITAGAWA, Satoko Nakamura, Naomi Akazawa, Genjiro Kusano   +4 more
openalex   +2 more sources

Electrochemical Hydrogenation of N‐Heterocycles and Related Substrates: A Mini‐Review

Electrochemical Science Advances, EarlyView.
ABSTRACT Catalytic hydrogenation refers to the (often) metal‐mediated addition of dihydrogen (H2) equivalents to unsaturated compounds to form new element‐hydrogen bonds. This conceptually simple reaction is ubiquitous in the production of a vast number of essential chemicals.
Esteban Garcia‐Torres, David E. Herbert   +1 more
wiley   +1 more source

Organocyclophosphazenes and Materials Based on Them for Pharmaceuticals and Biomedicine. [PDF]

Biomolecules
Yudaev P, Tupikov A, Chistyakov E.
europepmc   +1 more source