Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT N‐Nitrosamines (NAs) are probable human carcinogens and were detected as impurities in pharmaceuticals, which led to a concern for human health. NAs require metabolic activation before they become mutagenic, and not all NAs are mutagenic since their reactivity is related to their structure.
M. E. Geijer +4 more
wiley +1 more source
Optimization of Cyclophilin B-Targeted Tri-vector Inhibitors for Novel MASH Treatments. [PDF]
J Med ChemKouridaki ME +16 more
europepmc +1 more source
PYRROLIDINE DITHIOCARBAMATE (PDTC) HAS NO EFFECT ON SURVIVAL IN BURN WOUND SEPSIS. [PDF]
, 2002 David Peng +3 more
openalex +1 more source
Design, Synthesis, Biological Evaluation and Molecular Docking Studies of New Thiazolidinone Derivatives as NNRTIs and SARS-CoV-2 Main Protease Inhibitors. [PDF]
Chem BiodiversFesatidou M, Petrou A, Geronikaki A.
europepmc +1 more source
Multifunctional Heterocyclic Scaffolds for Hybrid Lewis Acid/Lewis Base Catalysis of Carbon–Carbon Bond Formation [PDF]
, 2016 Benoit, Adam R. +8 more
core +1 more source
The glutamate-dependent acid resistance system ofEscherichia coliandShigella flexneriis inhibited in vitro by l-trans-pyrrolidine-2,4-dicarboxylic acid [PDF]
, 2003 Scott R. Waterman, Pamela L. C. Small
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The Journal of Clinical Pharmacology, EarlyView.Abstract Levetiracetam is an antiseizure medication (ASM) that has several advantages over other ASMs, such as dose‐proportional pharmacokinetics, high bioavailability, and minimal drug interactions. The drug is primarily eliminated through the kidneys. Therefore, dose adjustments are necessary in patients with renal impairment or patients experiencing
Maged Kharouba +3 more
wiley +1 more source
<i>N</i>-Oxide Insertion into LDA Dimeric Aggregates for Azomethine Ylide Formation: Explicit Solvation in Quantum Mechanical Treatment of Polarized Intermediates. [PDF]
J Org ChemNeal MJ +10 more
europepmc +1 more source