Continuous-flow synthesis of 1,4,6,7-tetrahydro-5<i>H</i>-[1,2,3]triazolo[4,5-<i>c</i>]pyridines towards key intermediates of clinical candidates JNJ-54175446 and zanvipixant (JNJ-55308942) with antidepressant activity. [PDF]
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Domino Grignard Addition/Cope-House Reaction for the Synthesis of Polyhydroxylated 3-Methylindolizidines Analogous to Castanospermine. [PDF]
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The structural requirements of 3,5-substituted oxindoles that determine selective AMPK or GSK3β inhibition. [PDF]
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Aryl iodane-induced cascade arylation-1,2-silyl shift-heterocyclization of propargylsilanes under copper catalysis. [PDF]
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Synthesis and Biological Activity Study of Some New Substituted Pyrrolidines
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Pyrrolidine synthesis via ring contraction of pyridines. [PDF]
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Molecular networking derived from untargeted LC-MS/MS analysis to discover inhibitors of RANKL-induced osteoclastogenesis from Egyptian marine sponge-associated fungi. [PDF]
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An Inverse Electron-Demand Diels-Alder Approach to Selective Activity-Based Sensing of Acetaldehyde in Living Cells. [PDF]
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