Results 281 to 290 of about 70,546 (390)
Unusual Thermo-Enhanced Second Harmonic Generation in Organic Configurationally-Locked Polyene Crystals. [PDF]
Liu Y+9 more
europepmc +1 more source
How eriophyid mites shape metal metabolism in leaf galls on Tilia cordata
Summary Metal metabolism in plant–galler interactions is largely unknown. We hypothesise that the mites manipulate metal distribution by sequestration of excessive levels and differential regulation of metalloproteins to support the main functions of gall‐nutrition, protection and microenvironment.
Filis Morina+8 more
wiley +1 more source
The review focuses on relationships of oxadiazole derivative structures and their antimycobacterial activity including target structures in mycobacteria, in vitro or in vivo pharmacokinetic parameters, and toxicity. Apart from direct antimycobacterial activity, some 1,2,4‐oxadiazole derivatives can potentiate the antimycobacterial effect of ethionamide
Marta Kučerová‐Chlupáčová
wiley +1 more source
Phosphorylated Nitrones-Synthesis and Applications. [PDF]
Rozpara I+3 more
europepmc +1 more source
Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands
This study highlights the tetrahydropyrrolo[3,4‐c]pyrazole scaffold as a promising platform for S1R ligands development. Key findings include compound 19’s high S1R affinity (Ki=75 nM), influenced by strategic nitrogen substitutions and reduced steric hindrance.
Giuseppe Cosentino+7 more
wiley +1 more source
Enzymatic Production of Opine‐Type Chiral Amines with Controlled Stereoselectivity
The remarkable behavior of a ketimine reductase to enable control over the newly formed stereocenter in the reductive amination between α‐keto acids and α‐amino esters is reported. Mechanistic understanding for this unique property is provided at the molecular level within the enzyme active site.
András Telek+5 more
wiley +1 more source
Organocatalyzed Enantioselective [3+2] Cycloaddition Reactions for Synthesis of Dispiro[benzothiophenone-indandione-pyrrolidine] Derivatives. [PDF]
Liu HY, Du DM.
europepmc +1 more source
Skeletal Rearrangements of Amides via Breaking Inert Bonds
This review highlights advances in amide skeletal rearrangement reactions over the past two decades, categorized by the initial bond cleavages: C─N bond cleavage, C─C bond cleavage, and C═O bond activation. It summarizes emerging strategies, mechanistic insights, and synthetic applications, providing a focused perspective on recent developments in this
Rui Zhang, Guangbin Dong
wiley +1 more source