Results 301 to 310 of about 70,546 (390)

Structure-Activity Relationship of Pyrrolidine Pentamine Derivatives as Inhibitors of the Aminoglycoside 6'-N-Acetyltransferase Type Ib. [PDF]

Antibiotics (Basel)
Sklenicka J, Tran T, Ramirez MS, Donow HM, Magaña AJ, LaVoi T, Mamun Y, Jimenez V, Chapagain P, Santos R, Pinilla C, Giulianotti MA, Tolmasky ME.   +12 more
europepmc   +1 more source

Recycling Agricultural Waste: Sustainable Solutions for Enhancing Livestock Nutrition

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
The increasing demand for sustainable agricultural practices prompts a reevaluation of feeding strategies in ruminant nutrition. Agricultural waste, often viewed as a by‐product, presents a promising opportunity to enhance the sustainability of livestock production systems.
Mohsen Kazemi
wiley   +1 more source

Organocatalytic Packed-Bed Reactors for the Enantioselective Flow Synthesis of Quaternary Isotetronic Acids by Direct Aldol Reactions of Pyruvates. [PDF]

Molecules
Poletti L, De Risi C, Ragno D, Di Carmine G, Tassoni R, Massi A, Dambruoso P.   +6 more
europepmc   +1 more source

Synthesis of 1’-N-homoazanucleosides as potential transition state analogues and antiviral agents [PDF]

, 2016
Bouton, Jakob, Van Calenbergh, Serge
core  

Assessment of Spinster homologue 2 (Spns2)‐dependent transport of sphingosine‐1‐phosphate as a therapeutic target

British Journal of Pharmacology, Volume 182, Issue 9, Page 2014-2030, May 2025.
Abstract Background and Purpose Sphingosine‐1‐phosphate (S1P) receptor modulator (SRM) drugs suppress immune system function by disrupting lymphocyte trafficking, but SRMs are broadly immunosuppressive with on‐target liabilities. Another strategy to modulate the immune system is to block S1P transport.
Yugesh Kharel, Tao Huang, Kyle Dunnavant, Daniel Foster, George M. P. R. Souza, Katherine E. Nimchuk, Andrea R. Merchak, Caitlin M. Pavelec, Zuzanna J. Juskiewicz, Simon S. Alexander, Alban Gaultier, Stephen B. G. Abbott, Jung‐Bum Shin, Brant E. Isakson, Wehao Xu, Norbert Leitinger, Webster L. Santos, Kevin R. Lynch   +17 more
wiley   +1 more source

Hypervalent iodine-mediated cyclization of bishomoallylamides to prolinols. [PDF]

Beilstein J Org Chem
Butt SE, Kepski K, Sotiropoulos JM, Moran WJ.   +3 more
europepmc   +1 more source

Synthesis Methods and Therapeutic Journey of Carprofen and Its Derivatives: A Review

Chemical Biology &Drug Design, Volume 105, Issue 5, May 2025.
Although it is currently only used in veterinary therapy, carprofen proves to be a molecule with a versatile therapeutic potential for human pharmacotherapy. Moreover, the molecule is a target in the drug discovery process for the development of new bioactive compounds.
Carmen Limban, Diana Camelia Nuță, Miron Teodor Caproiu, Denisa Elena Dumitrescu, Șerban Iancu Papacocea, Alexandra Teodora Bordei, Florea Dumitrașcu   +6 more
wiley   +1 more source

Simple accessible clemastine fumarate analogues as effective antileishmanials. [PDF]

RSC Med Chem
Charlton RL, Escrivani DO, Brown C, Thota N, Agostino VS, Porta EOJ, Avkiran T, Merritt AT, Denny PW, Rossi-Bergmann B, Steel PG.   +10 more
europepmc   +1 more source

Zwitterionic (pyrrolidine-2,2-diyl)bisphosphonic acid at 100, 150 and 293K

, 2000
Gilles Olive, Diane D. Ellis, Didier Siri, François Le Moigne, Martin Lutz, Anthony L. Spek, Paul Tordo, Jean-Pierre Reboul   +7 more
openalex   +1 more source

Recent Advancements in the Cyclization Strategies of 1,3‐Enynes Towards the Synthesis of Heterocyclic/Carbocyclic Frameworks

Chemistry – An Asian Journal, Volume 20, Issue 8, April 17, 2025.
In this review, the advancements in the cyclization of 1,3‐enynes to construct structurally diverse heterocyclic and carbocyclic frameworks are portrayed comprehensively. Divergent cyclization protocols along with mechanistic aspects for key transformations are also detailed. Abstract 1,3‐Enynes have demonstrated their utility as valuable precursors to
Akash P. Sakla, Shams Aaghaz, Shujauddin Ahmed, Naziya Neshat, Ahmed Kamal   +4 more
wiley   +1 more source