Results 181 to 190 of about 17,768 (339)

A New synthesis of 4,5,6,7‐tetrahydrofuro[2,3‐c]pyridines and furo[2,3‐c]pyrrolidines [PDF]

, 1990
Anna Arnoldi, Giovanna Bregante, Patrizia Caldirola, Lucio Merlini, B. TAMBURINI   +4 more
openalex   +1 more source

Clinical Evaluation of Potential Interaction Between Bemnifosbuvir and Ruzasvir With an Assessment of Food Effect: Results of a Phase 1 Study in Healthy Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A combination of nucleotide hepatitis C virus (HCV) nonstructural protein (NS) 5B and 5A inhibitors is a preferred standard of care for treating chronic HCV. Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan‐genotypic inhibitory activity against HCV NS5B.
Xiao‐Jian Zhou, Gaetano Morelli, Maureen Montrond, Shannan Lynch, Keith Pietropaolo, Bruce Belanger, Arantxa Horga, Janet Hammond   +7 more
wiley   +1 more source

Synthesis of Pyrrolidine Derivatives with Pharmacological Activity. V. : Synthesis of α-Cycloalkyl-α-phenyl-3-pyrrolidinemethanol Derivatives

, 1969
S. OHKI, Yunosuke Nagase, MOTOYO YOSHINO, TEIKO AZUMA, Fumiko Hamaguchi   +4 more
openalex   +2 more sources

An Asymmetric Reduction of Prochiral Ketones with a Chiral Hydride Reagent Prepared from Lithium Aluminium Hydride and (S)-2-(2,6-Xylidinomethyl)pyrrolidine

, 1979
Teruaki Mukaiyama, Masatoshi Asami
openalex   +1 more source

Harnessing Fluorine Chemistry: Strategies for Per‐ and Polyfluoroalkyl Substances Removal and Enrichment

ChemPlusChem, EarlyView.
The high fluorine content in per‐ and polyfluoroalkyl substances (PFAS) gives them unique properties, leading to their widespread use in industrial applications and consumer products, but also creating environmental challenges . A thorough understanding of PFAS fluorine chemistry is crucial for developing effective concentration technologies ...
Anne Lobitz, Alex Steuber, Shang Jia, Lei Guo   +3 more
wiley   +1 more source

Selective C-N Bond Cleavage in Unstrained Pyrrolidines Enabled by Lewis Acid and Photoredox Catalysis. [PDF]

J Am Chem Soc
Aida K, Hirao M, Saitoh T, Yamamoto T, Einaga Y, Ota E, Yamaguchi J.   +6 more
europepmc   +1 more source

The Therapeutic Potential of Spirooxindoles in Cancer: A Focus on p53-MDM2 Modulation. [PDF]

Pharmaceuticals (Basel)
Girgis AS, Zhao Y, Nkosi A, Ismail NSM, Bekheit MS, Aboshouk DR, Aziz MN, Youssef MA, Panda SS.   +8 more
europepmc   +1 more source

Determination of a Trace Amount of Cadmium in Water by Atomic Absorption Spectrophotometry Combined with Ammonium Pyrrolidine Dithiocarbamate-Methyl Isobutyl Ketone Extraction Using Large Aqueous Phase/Solvent Ratios

, 1971
Yuroku Yamamoto, Takahiro Kumamaru, Yasuhisa Hayashi, Makoto Kanke   +3 more
openalex   +2 more sources

Design, synthesis, and antitumor activity of novel dispiro[oxindole-cyclohexanone]-pyrrolidines [PDF]

, 2022
Azab, Mohamed, Bawzeer, Majed, Elagawany, Mohamed, Elgendy, Bahaa, Gouda, Magy, Hegazy, Lamees, Rateb, Mostafa, Yaseen, Mohammed   +7 more
core   +1 more source

En Route Toward Sustainable Polycarbonates Via Large Cyclic Carbonates

ChemSusChem, Accepted Article.
This review reports an up‐to‐date overview of the synthetic methodologies developed for the preparation of large cyclic organic carbonates with ≥ 6‐membered rings (6M‐CCs and above), highlighting the most sustainable synthetic pathways employing diols (including renewable‐based ones) and non‐hazardous carbonyl sources, e.g., linear organic carbonates ...
Francesco Della Monica, Arianna Brandolese, Graziano Di Carmine, Maurizio Selva, Giulia Fiorani, Lorella Izzo   +5 more
wiley   +1 more source