Results 201 to 210 of about 4,019 (234)
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Structure of the 2-Pyrrolidinone Monohydrate
Zeitschrift für Naturforschung B, 1999The X-ray crystal structure of the 1:1 adduct shows a complicated network of water and 2-pyrrolidinone molecules where the carbonyl oxygen atom of 2-pyrrolidinone forms hydrogen bonds with protons of two separate water molecules and the NH proton of the 2- pyrrolidinone molecule interacts with the oxygen atom of a third water molecule.
Päivi Pirilä+2 more
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Disposition of N-Vinyl-2-Pyrrolidinone in the Rat
Drug and Chemical Toxicology, 1984The disposition of N-[14C-vinyl]-2-pyrrolidinone was studied in male Sprague-Dawley rats following a single iv injection. Plasma levels of the intact compound dropped rapidly within the first 6 hours after dosing with a half life of 1.90 hours. Urinary excretion by 12 hours represented 74.9% of a 5 microCi dose while 18.7% was excreted into the bile by
G. A. Digenis+2 more
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ChemInform Abstract: Synthesis and Reactions of 3‐Pyrrolidinones
ChemInform, 2008AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. Hammouda+3 more
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Food and Chemical Toxicology, 1992
The percutaneous absorption has been investigated in rats of a mixture (3:2, w/w) of N-methyl-2-pyrrolidinone (NMP) and 2-pyrrolidinone (2-P), a combination intended for use as a vehicle in the formulation of an antimycotic drug to enhance skin penetration on dermal application, following co-administration of the two 14C-radiolabelled compounds by the ...
A.J. Hood+5 more
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The percutaneous absorption has been investigated in rats of a mixture (3:2, w/w) of N-methyl-2-pyrrolidinone (NMP) and 2-pyrrolidinone (2-P), a combination intended for use as a vehicle in the formulation of an antimycotic drug to enhance skin penetration on dermal application, following co-administration of the two 14C-radiolabelled compounds by the ...
A.J. Hood+5 more
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ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
GHELFI, Franco+4 more
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
GHELFI, Franco+4 more
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ChemInform Abstract: Studies on Pyrrolidinones. On the Carbamoylation of Some Pyroglutamic Derivatives. [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Cauliez, P.+4 more
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Optimization of pyrrolidinone based HIV protease inhibitors
Bioorganic & Medicinal Chemistry Letters, 2005Optimization of P1-substituted pyrrolidinone based HIV protease inhibitors has yielded analogs with very potent antiviral activity.
Ronald George Sherrill+8 more
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2009
[872-50-4] C5H9NO (MW 99.15) InChI = 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3 InChIKey = SECXISVLQFMRJM-UHFFFAOYSA-N (special solvent;1 source of enolates2) Alternate Names: NMP; N-methylpyrrolidone. Physical Data: mp −24.4 °C; bp 202 °C; d 1.030 g cm−3.
Peteris Trapencieris, Julie A. Pigza
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[872-50-4] C5H9NO (MW 99.15) InChI = 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3 InChIKey = SECXISVLQFMRJM-UHFFFAOYSA-N (special solvent;1 source of enolates2) Alternate Names: NMP; N-methylpyrrolidone. Physical Data: mp −24.4 °C; bp 202 °C; d 1.030 g cm−3.
Peteris Trapencieris, Julie A. Pigza
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Journal of Chemical & Engineering Data, 2004
Experimental densities, ρ, viscosities, η, speeds of sound, υ, and relative permittivities, er, for three binary mixtures of water + 2-pyrrolidinone, + 1-methyl-2-pyrrolidinone, and + 1-vinyl-2-pyrrolidinone were measured over the entire composition range and at different temperatures.
John George and, Nandhibatla V. Sastry
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Experimental densities, ρ, viscosities, η, speeds of sound, υ, and relative permittivities, er, for three binary mixtures of water + 2-pyrrolidinone, + 1-methyl-2-pyrrolidinone, and + 1-vinyl-2-pyrrolidinone were measured over the entire composition range and at different temperatures.
John George and, Nandhibatla V. Sastry
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Journal of Physical Organic Chemistry, 1989
Abstract1H, 13C, 15N and 17O NMR chemical shifts, 1JNH and 1JCH coupling constants and line widths (Δν1/2) of the 14N and 17O resonance lines were determined for 2‐pyrrolidinone neat and for several 2‐pyrrolidinone–solvent systems. The 17O NMR chemical shift of 2‐pyrrolidinone was clearly most sensitive to the solvent effects, but changes with the ...
P. Ruostesuo+2 more
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Abstract1H, 13C, 15N and 17O NMR chemical shifts, 1JNH and 1JCH coupling constants and line widths (Δν1/2) of the 14N and 17O resonance lines were determined for 2‐pyrrolidinone neat and for several 2‐pyrrolidinone–solvent systems. The 17O NMR chemical shift of 2‐pyrrolidinone was clearly most sensitive to the solvent effects, but changes with the ...
P. Ruostesuo+2 more
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