Results 211 to 220 of about 4,019 (234)
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Journal of Atmospheric Chemistry, 2006
A study of the oxidation mechanism of N-methyl pyrrolidinone (C5H9NO, NMP) initiated by hydroxyl radicals was made at EUPHORE at atmospheric pressure (1000 ± 10) mbar of air and ambient temperature (T = 300 ± 5 K). The main products were N-methyl succinimide (NMS) (52 ± 4)% and N-formyl pyrrolidinone (FP) (23 ± 9)%. The relative rate technique was used
Amalia Muñoz+5 more
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A study of the oxidation mechanism of N-methyl pyrrolidinone (C5H9NO, NMP) initiated by hydroxyl radicals was made at EUPHORE at atmospheric pressure (1000 ± 10) mbar of air and ambient temperature (T = 300 ± 5 K). The main products were N-methyl succinimide (NMS) (52 ± 4)% and N-formyl pyrrolidinone (FP) (23 ± 9)%. The relative rate technique was used
Amalia Muñoz+5 more
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Hypolipidemic Activity of Substituted 2-Pyrrolidinones in Rodents
Journal of Pharmaceutical Sciences, 1983A series of substituted 2-pyrrolidinones was evaluated for hypolipidemic activity at 20 and 30 mg/kg/day in CF1 male mice. 4-Phenyl-5,5-dicarbethoxy-2-pyrrolidinone was the most potent compound at 30 mg/kg/day, reducing serum triglyceride levels 52% after 14 days of dosing and serum cholesterol levels 48% after 16 days of dosing.
Iris H. Hallx+3 more
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Pyrrolidinone and Piperidinone Isocyanides from Isocyano Esters
European Journal of Organic Chemistry, 2014AbstractThe alkylation of isocyano esters with 1,2‐ and 1,3‐dibromoalkanes affords bromo isocyanides. Under treatment with various amines the latter form new isocyano‐substituted lactams, which can be further used in Passerini or Ugi reactions.
Ait Sidhoum, Naïm+3 more
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Environmental and Molecular Mutagenesis, 1988
AbstractA number of solvent compounds that were tested in Saccharomyces cerevisiae were potent inducers of aneuploidy, although they did not induce any other genetic effects. As an extention of these earlier findings, 1‐methyl‐2‐pyrrolidinone was tested and was found to induce aneuploidy.
Vernon W. Mayer+2 more
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AbstractA number of solvent compounds that were tested in Saccharomyces cerevisiae were potent inducers of aneuploidy, although they did not induce any other genetic effects. As an extention of these earlier findings, 1‐methyl‐2‐pyrrolidinone was tested and was found to induce aneuploidy.
Vernon W. Mayer+2 more
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Journal of Labelled Compounds and Radiopharmaceuticals, 1985
AbstractAn efficient synthesis of 2‐pyrrolidinone and N‐methyl‐2‐pyrrolidinone was developed in which the compounds can be labeled with tritium at either the 3‐ and 4‐positions or the 4‐position of the lactam ring. Cyclization of [2,3‐3H]‐γ‐aminobutyric acid (GABA) yielded [3,4‐3H]‐2‐pyrrolidinone and cyclization of [3‐3H]‐GABA, prepared by acid ...
George A. Digenis+2 more
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AbstractAn efficient synthesis of 2‐pyrrolidinone and N‐methyl‐2‐pyrrolidinone was developed in which the compounds can be labeled with tritium at either the 3‐ and 4‐positions or the 4‐position of the lactam ring. Cyclization of [2,3‐3H]‐γ‐aminobutyric acid (GABA) yielded [3,4‐3H]‐2‐pyrrolidinone and cyclization of [3‐3H]‐GABA, prepared by acid ...
George A. Digenis+2 more
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Thermodynamic investigation of surfactant aggregation in 2-pyrrolidinone
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2002Abstract The partial molal volume (Vφ,s) of several surfactants viz. sodium dodecylsulphate (SDS) and sodium tetradecylsulfate (STS), tetraethylammonium bromide (Tea-Br), Span-80, 60, 40, 20 in 2-pyrrolidinone have been determined at concentration below 0.80 mol kg−1 at 30 and 40 °C.
Ila Joshi+2 more
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An Overview on Chemistry and Biological Importance of Pyrrolidinone
Current Organic Synthesis, 2018Background: Pyrrolidinone is a five membered heterocyclic ring that is a versatile lead compound for designing powerful bioactive agents. Pyrrolidinone nucleus is one of the most important heterocyclic compound indicating notable pharmaceutical effects.
Farideh Gouranlou+4 more
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Chemischer Informationsdienst, 1982
AbstractDie aus dem Diester (Ia) und einem großen Überschuß Natronlauge erhaltene Dicarbonsäure (Ib) wird in das Anhydrid (II) umgewandelt, dessen Ethanolyse zu den Estern (III) führt.
Miklós Hollósi+3 more
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AbstractDie aus dem Diester (Ia) und einem großen Überschuß Natronlauge erhaltene Dicarbonsäure (Ib) wird in das Anhydrid (II) umgewandelt, dessen Ethanolyse zu den Estern (III) führt.
Miklós Hollósi+3 more
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Studies on Pyrrolidinones. A Silylated Approach to Fused Triazoles
Synthetic Communications, 1994AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
D. Couturier+4 more
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Atmospheric chemistry of 1-methyl-2-pyrrolidinone
Atmospheric Environment, 1999Rate constants for the atmospheric reactions of 1-methyl-2-pyrrolidinone with OH radicals, NO3 radicals and O3 have been measured at 296±2 K and atmospheric pressure of air, and the products of the OH radical and NO3 radical reactions investigated. Using relative rate techniques, rate constants for the gas-phase reactions of OH and NO3 radicals with 1 ...
Sara M. Aschmann, Roger Atkinson
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