Results 41 to 50 of about 172,060 (247)

Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety

International Journal of Molecular Sciences, 2018
Pyrrolizidine alkaloids (PA) are widely distributed in plants throughout the world, frequently in species relevant for human consumption. Apart from the toxicity that these molecules can cause in humans and livestock, PA are also known for their wide ...
Rute Moreira, David M. Pereira, P. Valentão, P. Andrade   +3 more
semanticscholar   +1 more source

Flavin-dependent monooxygenases as a detoxification mechanism in insects: new insights from the arctiids (lepidoptera). [PDF]

PLoS ONE, 2010
Insects experience a wide array of chemical pressures from plant allelochemicals and pesticides and have developed several effective counterstrategies to cope with such toxins.
Sven Sehlmeyer, Linzhu Wang, Dorothee Langel, David G Heckel, Hoda Mohagheghi, Georg Petschenka, Dietrich Ober   +6 more
doaj   +1 more source

Senecio ovatus poisoning in a horse - A case report

Veterinární Medicína
This study describes a case of poisoning by pyrrolizidine alkaloids in a horse. To the best of the author's knowledge, this is the first confirmed case of Senecio ovatus poisoning.
A Kopecka, T Novotna, Z Svobodova, Z Drabkova   +3 more
doaj   +1 more source

Pyrrolizidine alkaloids of senecio sp from Peru

Química Nova, 2011
Six pyrrolizidine alkaloids (PAs) (two saturated macrocyclic, three unsaturated macrocyclic and one unsaturated seco-macrocyclic) were isolated from native Peruvian Senecio species.
Liliana Ruiz Vásquez and Matías Reina Artiles, Azucena González Coloma, Raimundo Cabrera Pérez, Lastenia Ruiz Mesia   +3 more
doaj   +1 more source

Soil-borne microorganisms and soil-type affect pyrrolizidine alkaloids in Jacobaea vulgaris [PDF]

Secondary metabolites like pyrrolizidine alkaloids (PAs) play a crucial part in plant defense. We studied the effects of soil-borne microorganisms and soil-type on pyrrolizidine alkaloids in roots and shoots of Jacobaea vulgaris.
Joosten, L., Klinkhamer, P.G.L., Mulder, P.P.J., Veen, J.A., van   +3 more
core   +2 more sources

Pyrrolizidine alkaloids in herbal tea and honey: Report on the 2017 Proficiency testing scheme [PDF]

, 2017
Pyrrolizidine alkaloids (PAs) and their N-oxides (PANOs) are plant toxins which can enter the food chain through different paths. Two affected foods are herbal infusions and honey.
BREIDBACH ANDREAS, TAMOSIUNAS VYTAUTAS
core   +2 more sources

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Observation of Trigona recursa Smith (Hymenoptera: Apidae) Feeding on Crotalaria micans Link (Fabaceae: Faboideae) in a Brazilian Savanna Fragment

Sociobiology, 2013
In this paper we present observations of individuals of the bee species Trigona recursa feeding on the fruits of Crotalaria micans. This plant, which contains pyrrolizidine alkaloids, is known to be toxic to humans, mammals and poultry.
Thiago Mateus Rocha dos Santos, Julie Teresa Shapiro, Patricia S. Shibuya, Camila Aoki   +3 more
doaj   +3 more sources

Wild edible plants: Nutritional and toxicological characteristics, retrieval strategies and importance for today's society [PDF]

, 2017
Wild edible plants (WEPs) are part of the cultural and genetic heritage of different regions of the world. In times of famine and scarcity, these sources of nutrients and health-promoting compounds have received high importance mainly in rural and ...
Abbasi, Abdelli, Aceituno-Mata, Al-Qura'n, Alarcón, Amaducci, Amalraj, Amirul, Ana Maria Carvalho, Anderson, AOAC, Bacchetta, Baker, Barreira, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barros, Barroso, Bianco, Bicho, Brogren, Caldas, Caleja, Caleja, Caleja, Carocho, Carr, Carvalho, Carvalho, Carvalho, Castañeda-Álvarez, Chen, Chen, Chen, Costa, Cowan, Da Rocha, Dias, Dodson, EFSA, EFSA, EFSA, EMA, EMA, European Commission, Fajardo, Fernandes, Galli, García Herrera, García-Herrera, García-Herrera, García-Herrera, García-Jiménez, Gille, Glensk, Gry, Guerra, Guil, Guil-Guerrero, Guil-Guerrero, Guil-Guerrero, Guimarães, Gupta, Güçlü-Üstündağ, Hylands, Hylands, Isabel C.F.R. Ferreira, José Pinela, Kaur, Kaushik, Kemal, Kim, Kiuchi, Kovács, Kovács, Kristanc, Kristanc, Kumarasamy, Lee, Li, Liebman, Magos Brehm, Marostica, Martins, Martins, Martins, Mason, Maxted, Menendez-Baceta, Menendez-Baceta, Molina, Monzote, Morales, Morales, Morales, Morales, Morales, Morales, Muzquiz, Muñoz, Niki, Niki, Nikolić, Oda, Oliveira, Oobayashi, Ottaway, Otten, Palaniswamy, Pandey, Pardo-de-Santayana, Pereira, Pereira, Pereira, Petropoulos, Petropoulos, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Pinela, Podolak, Pohlmann, Quintaes, Radulović, Ranfa, Renna, Reyes-García, Roeder, Réthy, Saini, Schippmann, Simopoulos, Sinha, Smith, Smolarz, Smolin, Souci, Stein, Street, Swaminathan, Sánchez-Mata, Sánchez-Mata, Sõukand, Sõukand, Tardio, Tardío, Tardío, Tardío, Tardío, Teixeira, The European Parliment and the Council of the European Union, The Plant List, Thomassen, Torbati, Torija-Isasa, Trichopoulou, Tucker, Turner, Tuttolomondo, Vacillotto, Vasquez, Vermerris, Vermerris, Vinha, Vizgirdas, Wiedenfeld, Wretensjö, Wu, Zhang, Zhang, Zhao, Łuczaj, Łuczaj, Żołnierczyk   +183 more
core   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source