Results 51 to 60 of about 253,123 (156)

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis. [PDF]

Natural product reports (Print), 2017
This review covers the isolation and structure of new pyrrolizidines; pyrrolizidine biosynthesis; biological activity, including the occurrence of pyrrolizidines as toxic components or contaminants in foods and beverages; and formal and total syntheses ...
J. Robertson, K. Stevens
semanticscholar   +2 more sources

Comparative Study of the Antioxidant Mediated Antiaging Properties of Endocarp Extracts From Phoenix dactylifera and Phoenix dactylifera L. via In Silico and In Vitro Analysis

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This comparative study demonstrates that Phoenix dactylifera possesses higher anti‐aging potential compared to Phoenix dactylifera L., which may be attributed to their higher phenolic and flavonoid contents along with stronger free radical scavenging capacity.
Farheen Asaad, Mazhar Abbas, Waqas Haider, Naveed Munir, Maha Gul Zafar, Muhammad Riaz, Muhammad Arshad, Muhammad Arfan Zaman, Tariq Hussain, Muhammad Adnan Ayub, Hasan Ejaz, Quzi Sharmin Akter   +11 more
wiley   +1 more source

In Silico Prediction of Drug-Likeness, Pharmacokinetics, and Toxicity of Selected Phytotoxic Pyrrolizidine Alkaloids

Proceedings
Pyrrolizidine alkaloids (PAs) are heterocyclic organic compounds of natural origin synthesized by either plants or microorganisms [...]
Obinna Kenneth Didigwu, Emmanuel Amuchechukwu Kevin, Michael Osita Edeh, Sunday N. Okafor   +3 more
doaj   +1 more source

Neuroprotective Effects of Senecio brasiliensis Extract Against Chlorpyrifos‐Induced Neurotoxicity and Oxidative Stress in Drosophila melanogaster

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Chlorpyrifos (CP) is an organophosphate insecticide that induces neurotoxicity through acetylcholinesterase (AChE) inhibition and redox imbalance, raising environmental and occupational health concerns. Plant‐derived compounds from Senecio brasiliensis, native to the Pampa biome, offer multitarget therapeutic potential.
Maria Vitória Takemura Mariano, Giany Gabriely Padão dos Santos, Ana Beatriz Guedes de Souza, Thaís de Camargo Neves, Franklin Vinny Medina Nunes, Pedro Henrique Vicenzi, Karen Kich Gomes, Mauro Eugênio Medina Nunes, Marcelo Farina, Jeferson Luis Franco, Thaís Posser   +10 more
wiley   +1 more source

Ecology and evolution of pyrazines in insects

Biological Reviews, Volume 101, Issue 4, Page 1937-1959, August 2026.
ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk, Niklas Wahlberg, Johanna Mappes   +2 more
wiley   +1 more source

Tropane alkaloids in food [PDF]

, 2010
A large number of wild and cultured plants produce secondary metabolites that are toxic to humans and animals. Through accidental or intentional mixing of these plants with normal food and feed the consumers of these products will be exposed to the ...
Adamse, P., Egmond, H.P., van
core  

Inhibiting HIF‐1α‐Induced miR‐663b Improves Pulmonary Arterial Hypertension by Reducing Dysfunctions of PASMCs Through Repressing Sirt1‐ZBP1‐Mediated PANoptosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Pulmonary arterial hypertension (PAH) is a progressive disease characterised by vascular remodelling. Inflammatory responses and oxidative stress have been shown to contribute to its progression. This study investigated the effects of a novel HIF‐1α‐miR‐663b axis on pulmonary arterial smooth muscle inflammation, oxidative stress and apoptosis ...
Le Shen, Honghong Ma, Yang Yu, Yan Xu, Qun Yuan, Xia Zhao, Bing Zhuan   +6 more
wiley   +1 more source

Risks for human health related to the presence of pyrrolizidine alkaloids in honey, tea, herbal infusions and food supplements

EFSA journal. European Food Safety Authority, 2017
EFSA was asked by the European Commission to deliver a scientific opinion on the risks for human health related to the presence of pyrrolizidine alkaloids (PAs) in honey, tea, herbal infusions and food supplements and to identify the PAs of relevance in ...
H. Knutsen, J. Alexander, L. Barregard, M. Bignami, B. Brüschweiler, S. Ceccatelli, B. Cottrill, M. Dinovi, L. Edler, B. Grasl-Kraupp, C. Hogstrand, L. Hoogenboom, C. Nebbia, I. Oswald, A. Petersen, M. Rose, A. Roudot, T. Schwerdtle, C. Vleminckx, G. Vollmer, Heather M. Wallace, J. Á. Gómez Ruiz, Marco Binaglia   +22 more
semanticscholar   +1 more source

Pyrrolizidine alkaloids.

, 2014
This review covers pyrrolizidine alkaloids isolated from natural sources. Topics include: aspects of structure, isolation, and biological/pharmacological studies; total syntheses of necic acids, necine bases and closely-related non-natural ...
Robertson, J, Stevens, K, Robertson, Jeremy   +2 more
core   +1 more source