Results 71 to 80 of about 253,123 (156)

Pyrrolizidine Alkaloids: The Botanical Origin of Pollen Collected during the Flowering Period of Echium vulgare and the Stability of Pyrrolizidine Alkaloids in Bee Bread

open access: yesMolecules, 2019
Previous studies have shown that pollen products sold as nutritional supplements and used in apitherapy may contain toxic pyrrolizidine alkaloids (PAs) if bees collect pollen from PA-containing plants, such as Echium vulgare. In this study, the botanical
C. Kast   +4 more
semanticscholar   +1 more source

Lithium Diisopropylamide‐Mediated Ring‐Opening of Tetrahydrofuran in the Synthesis of Polyhydroxylated Indolizidines

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.
Chiral tri‐ and pentahydroxy spirocyclopentane‐indolizidines were synthesized using lithium diisopropylamide “LDA” promoted diallylation and tetrahydrofuran “THF” ring‐opening in a one‐pot procedure as a key step. The sequence leading to the targeted hydroxy‐spiroindolizidines was achieved by cis‐dihydroxylation followed by reduction of the enamine and
Paula Fraňová   +6 more
wiley   +1 more source

PHYTOCHEMICAL STUDY OF CROTALARIA THEBAICA (DEL.) DC. GROWING IN EGYPT [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1990
From the chloroformic extract of Crotalaria thebaica (Del.)Dc. herb, three pyrrolizidine alkaloids, Spectabiline, Monocrotaline and Crosemperine as well as b-sitosterol glycoside and daidzein were isolated.
K. Takeya   +5 more
doaj   +1 more source

GC-MS and LC-MS/MS workflows for the identification and quantitation of pyrrolizidine alkaloids in plant extracts, a case study: Echium plantagineum

open access: yesRevista Brasileira de Farmacognosia, 2019
Workflows based on gas and liquid chromatography coupled to mass spectrometry for the identification of toxic pyrrolizidine alkaloids present in plants were developed and applied to Echium plantagineum L., Boraginaceae, extracts.
A. Sixto   +3 more
semanticscholar   +1 more source

Evaluating the Suitability of HepaRG Cells for Regulatory Micronucleus Testing: Comparing Results for a Diverse Set of 28 Chemicals to Regulatory Accepted TK6 Cells

open access: yesEnvironmental and Molecular Mutagenesis, Volume 67, Issue 5-7, June‐August 2026.
ABSTRACT There is growing interest in in vitro‐based new approach methodologies (NAMs) for assessing genotoxicity. These approaches are desirable for industries like cosmetics which are prohibited from animal testing due to regulatory restrictions, as well as “3R” considerations to avoid in vivo testing.
Ashley Allemang, Stefan Pfuhler
wiley   +1 more source

Evaluation of sunn hemp performance and nutritive value in Maine, USA

open access: yesGrassland Research, Volume 5, Issue 2, Page 112-118, June 2026.
Abstract Background Sunn hemp (Crotalaria juncea L. and Crotalaria ochroleuca G. Don) was evaluated as a warm‐season legume to mitigate the “summer slump” in Maine's forage production caused by heat and moisture deficit stress. Methods This study compared three cultivars: “Crescent Sunn,” “Loei,” and “Red Mini,” at 60 and 90 days after seeding over the
Jaime Garzon, Edgar Cardenas
wiley   +1 more source

Presença de alcalóides pirrolizidinicos em Ageratum conyzoides L., Asteraceae [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em FarmáciaAgeratum conyzoides L. é conhecida popularmente como "mentrasto" e pertence à família Asteraceae.
Bosi, Cristiane Fracari
core  

Is the endophyte‐based plant protection against aphids mediated by changes in the insect microbiome?

open access: yesInsect Science, Volume 33, Issue 3, Page 1097-1108, June 2026.
We showed that the fungal endophyte Epichloë strain AR37 increased the plant resistance against aphids via the production of indole diterpene alkaloids. The reduction in aphid performance was not associated with changes in abundance/composition/diversity of the insect's bacterial microbiota, but additional endophyte effects on this microbiota cannot be
Daniel A. Bastías   +5 more
wiley   +1 more source

Pyrrolizidine alkaloids: Hepatic metabolism and extrahepatic toxicity

open access: yes, 1994
Pyrrolizidine alkaloids are proposed to be metabolized in the liver to reactive pyrrole species, or dehydroalkaloids. These reactive pyrroles are hypothesized to be responsible for pyrrolizidine alkaloid toxicity.
Wild, Stacie Lynn.
core   +5 more sources

Supinidine Viridiflorates from the Roots of

open access: yesNatural Product Communications, 2013
The alkaloid extract from the roots of Chromolaena pulchella provided two new pyrrolizidine alkaloids, elucidated as (-)-supinidine triviridiflorate ( 1 ) and (-)-supinidine diviridiflorate ( 2 ) based on their physical and spectroscopic properties ...
Mario A. Gómez-Hurtado   +7 more
doaj   +1 more source

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