Results 51 to 60 of about 172,060 (247)

Determination of pyrrolizidine alkaloids in dietary sources using a spectrophotometric method [PDF]

, 2018
Pyrrolizidine alkaloids (PAs) are a class of toxic compounds found in the composition of more than 6000 plants. People can be exposed to PAs by consuming phytotherapeutic products, food from crops contaminated with seeds of some species with high content
Diaconu, Camelia, Guțu, Claudia M, Ilie, Mihaela, Margină, Denisa, Motofei, Catalina, Negreș, Simona, Nițulescu, Mihai G, Olaru, Octavian T, Zbârcea, Cristina E, Șeremet, Oana C, Ștefănescu, Emil   +10 more
core   +1 more source

Is the endophyte‐based plant protection against aphids mediated by changes in the insect microbiome?

Insect Science, EarlyView.
We showed that the fungal endophyte Epichloë strain AR37 increased the plant resistance against aphids via the production of indole diterpene alkaloids. The reduction in aphid performance was not associated with changes in abundance/composition/diversity of the insect's bacterial microbiota, but additional endophyte effects on this microbiota cannot be
Daniel A. Bastías, Luis Carvalho, Ruy Jáuregui, Richard D. Johnson, Wei Zhang, Pedro E. Gundel   +5 more
wiley   +1 more source

In Silico Prediction of Drug-Likeness, Pharmacokinetics, and Toxicity of Selected Phytotoxic Pyrrolizidine Alkaloids

Proceedings
Pyrrolizidine alkaloids (PAs) are heterocyclic organic compounds of natural origin synthesized by either plants or microorganisms [...]
Obinna Kenneth Didigwu, Emmanuel Amuchechukwu Kevin, Michael Osita Edeh, Sunday N. Okafor   +3 more
doaj   +1 more source

Research Progress on Contamination Levels, Analytical Methods and Processing Effects of Pyrrolizidine Alkaloids in Food

Shipin gongye ke-ji, 2023
Pyrrolizidine alkaloids (PAs) are a class of natural toxins produced by plant secondary metabolism, of which unsaturated PAs and most pyrrolizidine alkaloid N-oxides (PANOs) have multiple toxic effects.
Hui LIU, Tongna MU, Li LIN, Jianqiang GENG, Jie JIANG   +4 more
doaj   +1 more source

Occurrence of pyrrolizidine alkaloids in animal- and plant-derived food: results of a survey across Europe

Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment, 2018
Pyrrolizidine alkaloids (PAs) are secondary metabolites of plant families such as Asteraceae or Boraginaceae and are suspected to be genotoxic carcinogens. Recent investigations revealed their frequent occurrence in honey and particularly in tea.
P. Mulder, Patricia López, Massimo Castelari, Dorina Bodi, S. Ronczka, A. Preiss-Weigert, A. These   +6 more
semanticscholar   +1 more source

AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives

Journal of Integrative Plant Biology, EarlyView.
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li, Tao Zeng, Hongquan Xu, Xu Kang, Minghui Liang, Ruibo Wu   +5 more
wiley   +1 more source

Traditional Herbal Medicine Use Associated with Liver Fibrosis in Rural Rakai, Uganda [PDF]

, 2012
Background: Traditional herbal medicines are commonly used in sub-Saharan Africa and some herbs are known to be hepatotoxic. However little is known about the effect of herbal medicines on liver disease in sub-Saharan Africa.
Aggrey S. Semeere, Anthony Ndyanabo, Brandon J. Auerbach, Collins Kukunda-Byobona, Concepta Merry, David L. Thomas, Fred Nalugoda, Gregory D. Kirk, Iga Boaz, Lara Stabinski, Maria J. Wawer, Mohammed Lamorde, null null, Ponsiano Ocama, Ron H. Gray, Steven J. Reynolds, Thomas C. Quinn, Valerian Kiggundu   +17 more
core   +2 more sources

Pyrrolizidine Alkaloids: The Botanical Origin of Pollen Collected during the Flowering Period of Echium vulgare and the Stability of Pyrrolizidine Alkaloids in Bee Bread

Molecules, 2019
Previous studies have shown that pollen products sold as nutritional supplements and used in apitherapy may contain toxic pyrrolizidine alkaloids (PAs) if bees collect pollen from PA-containing plants, such as Echium vulgare. In this study, the botanical
C. Kast, V. Kilchenmann, H. Reinhard, K. Bieri, O. Zoller   +4 more
semanticscholar   +1 more source

Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research

Mass Spectrometry Reviews, Volume 45, Issue 2, Page 429-452, March/April 2026.
ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke, Liang Jiang, Morphy Dumlao, William A. Donald   +3 more
wiley   +1 more source

Differences in Effects of Pyrrolizidine Alkaloids on Five Generalist Insect Herbivore Species [PDF]

, 2018
The evolution of the diversity in plant secondary compounds is often thought to be driven by insect herbivores, although there is little empirical evidence for this assumption.
Bruinsma, Maaike, Dijkstra, Sander, Klinkhamer, Peter, Macel, Mirka, Niemeyer, Hermann, Ooijendijk, Tessa   +5 more
core