Results 171 to 180 of about 141,799 (322)

Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet. [PDF]

open access: yesJ Biol Chem, 2022
Selen ES   +5 more
europepmc   +1 more source

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver.

open access: yesCell Metabolism, 2019
David A. Cappel   +13 more
semanticscholar   +1 more source

Stimulation of High‐Conductivity Points in Human Skin Reduces Biotin Levels to Modulate Intracellular Metabolism and Local Energy Production

open access: yesHealth Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Acupuncture is a widely used therapeutic practice that targets specific points on or beneath the skin, known as acupoints. While acupoints are thought to exhibit low electrical resistance, their underlying biophysical and molecular characteristics remain incompletely understood.
Kazuki Takagaki   +6 more
wiley   +1 more source

Quantitative decoding of coupled carbon and energy metabolism in Pseudomonas putida for lignin carbon utilization

open access: yesCommunications Biology
Soil Pseudomonas species, which thrive on lignin derivatives, are widely explored for biotechnology applications in lignin valorization. However, how the native metabolism coordinates phenolic carbon processing with required cofactor generation remains ...
Nanqing Zhou   +8 more
doaj   +1 more source

In silico Analysis of Two Novel Variants in the Pyruvate Carboxylase (PC) Gene Associated with the Severe Form of PC Deficiency. [PDF]

open access: yesIran Biomed J, 2023
Maryami F   +6 more
europepmc   +1 more source

Ketogenic Nutrition in Combination With PPARα Activation Induced Metabolic Failure and Exacerbated Muscle Weakness in Septic Mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Suppression of the peroxisome proliferator‐activated receptor alpha (PPARα) has been related to poor outcomes in sepsis and may compromise ketogenesis during critical illness. Infusion of 3‐hydroxybutyrate (3HB) was shown to attenuate muscle weakness in septic mice.
Caroline Lauwers   +12 more
wiley   +1 more source

Dynamic Evolution of the Tumor Immune Microenvironment in Malignant Tumors and Emerging Therapeutic Paradigms

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Cancer is a complex tumor system consisting of tumor cells, immune effector cells, and all the matrix components. The intricate interactions among cells and molecular signaling pathways in this microenvironment jointly drive tumor growth, invasion, and metastasis, and significantly influence the efficacy of cancer treatment. Meanwhile, the treatment of
Ying Sun   +11 more
wiley   +1 more source

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