Results 51 to 60 of about 13,382 (149)

Characterisation of aerotolerant forms of a robust chicken colonizing Campylobacter coli [PDF]

, 2017
Campylobacter contaminated poultry meat is a major source of human foodborne illness. Campylobacter coli strain OR12 is a robust colonizer of chickens that was previously shown to outcompete and displace other Campylobacter strains from the chicken’s ...
Al-Haideri, Atack, Atack, Atack, Benesch, Blaser, Bleumink-Pluym, Bolton, Bronnec, Brown, Bury-Moné, Chynoweth, Conlan, Douidah, EFSA, EFSA, EFSA, El-Shibiny, El-Shibiny, El-Shibiny, El-Shibiny, Flint, Flint, Flint, Fouts, Garénaux, Gaynor, Ghaffar, Gillespie, Goss, Guerry, Gundogdu, Hermans, Hobb, Hwang, Imlay, Inatsuka, Jacobs-Reitsma, Jeanson, John, Jones, Kaakoush, Loc Carrillo, McNally, Miles, Miller, Moreno, Oh, O’Brien, Palyada, Parkhill, PHE, Purdy, Reyrolle, Ribot, Rodrigues, Rutherford, Scott, Sheppard, Smith, Speegle, Stahl, Stern, Takamiya, Tam, Theoret, van Gerwe, Vegge, Velayudhan, Velayudhan, Wagley, WHO, Wilson   +72 more
core   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis

Glia, Volume 74, Issue 3, March 2026.
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco, Matteo Audano, Rosa La Marca, Marta Pellegatta, Paolo Canevazzi, Mariaconcetta Cariello, Marta Falco, Silvia Pedretti, Gabriele Imperato, Alessandro Cestaro, Paola Podini, Giorgia Dina, Angelo Quattrini, Luca Massimino, Donatella Caruso, Nico Mitro, Carla Taveggia   +16 more
wiley   +1 more source

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer [PDF]

, 2018
During tumorigenesis, the high metabolic demand of cancer cells results in increased production of reactive oxygen species. To maintain oxidative homeostasis, tumor cells increase their antioxidant production through hyperactivation of the NRF2 pathway ...
Altman, Biancur, Boulahbel, Briggs, Cairns, Cancer Genome Atlas Research Network, Chandel, Chio, Cong, Cox, Davidson, Davies, DeBerardinis, DeBerardinis, DeBerardinis, Deberardinis, DeNicola, Dixon, Fabrizio, Fellmann, Fernandez, Gaglio, Gao, Goldstein, Gorrini, Habib, Hanada, Hanahan, Hosios, Hu, Ishii, Itoh, Itoh, Jaramillo, Kim, King, Kobayashi, Konermann, Konstantinopoulos, Koppula, Lacey, Lane, Larson, Le Gal, Letouzé, Lewerenz, Lewis, Loenarz, Mayers, Mitsuishi, Muscarella, Nicklin, Nioi, Piskounova, Qie, Rhoads, Romero, Sato, Sayin, Sayin, Selak, Shibata, Shibata, Shin, Singh, Sleeman, Son, Taguchi, Tardito, Timmerman, Trachootham, Vander Heiden, Warburg, Watanabe, Waterfall, Welbourne, Wise, Wise, Xiang, Xiao, Yuneva, Yuneva   +81 more
core   +1 more source

Understanding the dynamic nature of plant lipid anabolic and catabolic metabolism is key to sustainable oilseed engineering

New Phytologist, Volume 249, Issue 5, Page 2196-2214, March 2026.
Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri, Sean T. McGuire, Matthew G. Garneau, Niña Alyssa M. Barroga, Philip D. Bates   +4 more
wiley   +1 more source

Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion [PDF]

, 2001
A female infant of nonconsanguineous Indian parents presented at 4 months with a hypoglycemic convulsion. Further episodes of hypoketotic hypoglycemia were associated with inappropriately elevated plasma insulin concentrations.
Aynsley-Green, A, Berger, R, Clayton, PT, Datta, V, Eaton, S, Edginton, M, Hussain, K, Krywawych, S, Malingre, HEM, van den Berg, IET   +9 more
core  

Salmonella enterica: a surprisingly well-adapted intracellular lifestyle [PDF]

, 2012
The infectious intracellular lifestyle of Salmonella enterica relies on the adaptation to nutritional conditions within the Salmonella-containing vacuole (SCV) in host cells.
Dandekar, Thomas, Fieselmann, Astrid, Hensel, Michael, Popp, Jasmin   +3 more
core   +2 more sources

Direct AMPK Activation Confers Mutation‐Independent Therapeutic Benefit in Duchenne Muscular Dystrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is a severe, life‐limiting neuromuscular disorder (NMD) characterized by progressive muscle wasting and mitochondrial dysfunction. Although gene therapies offer promise, even those already approved by regulatory agencies, their use remains constrained by mutation specificity, delivery challenges and
Sean Y. Ng, Andrew I. Mikhail, Stephanie R. Mattina, Magda A. Lesinski, Irena A. Rebalka, Sophie I. Hamstra, Donald Xhuti, Val A. Fajardo, Mark A. Tarnopolsky, Joshua P. Nederveen, Gregory R. Steinberg, Thomas J. Hawke, Vladimir Ljubicic   +12 more
wiley   +1 more source

Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI

Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 310-327, February 2026.
ABSTRACT Conventional Magnetic Resonance Imaging (MRI) offers limited sensitivity for direct metabolic and molecular imaging using non‐proton nuclei due to low thermal nuclear spin polarization. Hyperpolarization (HP) technologies increase nuclear spin polarization by several orders of magnitude, overcoming this limitation to enable in vivo studies of ...
Alixander S. Khan, Christoffer Laustsen
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source