Results 11 to 20 of about 124,495 (263)

Characterization of the L-lactate dehydrogenase from Aggregatibacter actinomycetemcomitans. [PDF]

PLoS ONE, 2009
Aggregatibacter actinomycetemcomitans is a Gram-negative opportunistic pathogen and the proposed causative agent of localized aggressive periodontitis. A.
Stacie A Brown, Marvin Whiteley
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The pyruvate dehydrogenase kinase 2 (PDK2) is associated with conidiation, mycelial growth, and pathogenicity in Fusarium graminearum

Food Production, Processing and Nutrition, 2020
Pyruvate dehydrogenase kinase (PDK) is a mitochondrial enzyme in a variety of eukaryotes, including the plant pathogen Fusarium graminearum. This enzyme can reduce the oxidation of glucose to acetyl-coA by phosphorylation and selectively inhibits the ...
Tao Gao, Dan He, Xin Liu, Fang Ji, Jianhong Xu, Jianrong Shi   +5 more
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Anaesthesia and pyruvate dehydrogenase deficiency [PDF]

Canadian Anaesthetists’ Society Journal, 1983
A ten-month-old infant with pyruvate dehydrogenase deficiency received anaesthesia on two occasions, once for a laparotomy and once for a tracheostomy. During both anaesthetics (different techniques) she developed an increase in arterial lactate levels and a metabolic acidosis.
S F, Dierdorf, W L, McNiece
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The effect of phosphorylation on pyruvate dehydrogenase [PDF]

FEBS Letters, 1995
Phosphorylation of the pyruvate dehydrogenase component (E1) of the muscle pyruvate dehydrogenase complex (PDC) by E1‐kinase inhibits substrate conversion both in oxidative and non‐oxidative reactions. Circular dichroism spectra were used to monitor the effect of phosphorylation on the following stages of the process: holoform formation from apo‐E1 and
Korotchkina, L.G., Khailova, L.S., Severin, S.E.   +2 more
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Lactic Acid Fermentation Is Required for NLRP3 Inflammasome Activation

Frontiers in Immunology, 2021
Activation of the Nod-like receptor 3 (NLRP3) inflammasome is important for activation of innate immune responses, but improper and excessive activation can cause inflammatory disease.
Hsin-Chung Lin, Hsin-Chung Lin, Yu-Jen Chen, Yu-Jen Chen, Yu-Jen Chen, Yau-Huei Wei, Hsin-An Lin, Chien-Chou Chen, Tze-Fan Liu, Yi-Lin Hsieh, Kuo-Yang Huang, Kuan-Hung Lin, Hsueh-Hsiao Wang, Lih-Chyang Chen   +13 more
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Conformational features of lactate dehydrogenase: temperature effect in presence of small molecules, mathematical model

Бюллетень сибирской медицины, 2020
The aim of this work was to study the conformational changes of lactate dehydrogenase under the influence of different concentrations of intermediates (pyruvate, oxaloacetate) in the temperature gradient with the  subsequent building of a mathematical ...
F. N. Gilmiyarova, V. I. Kuzmicheva, N. A. Kolotyeva, M. V. Komarova, E. A. Ryskina, O. A. Gusyakova, D. S. Vinogradova, V. V. Salmin   +7 more
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Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers [PDF]

Diabetes & Metabolism Journal, 2015
Impaired glucose homeostasis is one of the risk factors for causing metabolic diseases including obesity, type 2 diabetes, and cancers. In glucose metabolism, pyruvate dehydrogenase complex (PDC) mediates a major regulatory step, an irreversible reaction
Nam Ho Jeoung
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Pyruvate dehydrogenase deficiency: morphological and metabolic effects, creation of animal model to search for curative treatment

Folia Morphologica, 2020
The main source of energy for brain and other organs is glucose. To obtain energy for all tissue, glucose has to come through glycolysis; then as pyruvate it is converted to acetyl-CoA by pyruvate dehydrogenase complex (PDC) and finally enters citric ...
A. Ebertowska, B. Ludkiewicz, I. Klejbor, N. Melka, J. Moryś   +4 more
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Transcriptional Regulation of Pyruvate Dehydrogenase Kinase [PDF]

Diabetes & Metabolism Journal, 2012
The pyruvate dehydrogenase complex (PDC) activity is crucial to maintains blood glucose and ATP levels, which largely depends on the phosphorylation status by pyruvate dehydrogenase kinase (PDK) isoenzymes.
Ji Yun Jeong, Nam Ho Jeoung, Keun-Gyu Park, In-Kyu Lee   +3 more
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Regulation of Cardiac-Specific Proteins Expression by Moderate-Intensity Aerobic Exercise Training in Mice With Myocardial Infarction Induced Heart Failure Using MS-Based Proteomics

Frontiers in Cardiovascular Medicine, 2021
This study aims to systematically reveal the changes in protein levels induced by regular exercise in mice with ischemic-induced heart failure (HF). Aerobic exercise training for the ischemic-induced HF mice lasted for 4 weeks and then we used the liquid
Shouling Mi, Shouling Mi, Hao Jiang, Hao Jiang, Lei Zhang, Zhonglei Xie, Zhonglei Xie, Jingmin Zhou, Jingmin Zhou, Aijun Sun, Aijun Sun, Aijun Sun, Hong Jin, Hong Jin, Junbo Ge, Junbo Ge, Junbo Ge   +16 more
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