Results 201 to 210 of about 124,495 (263)

Regulating the metabolic flux of pyruvate dehydrogenase bypass to enhance lipid production in Saccharomyces cerevisiae. [PDF]

Commun Biol
Lei C, Guo X, Zhang M, Zhou X, Ding N, Ren J, Liu M, Jia C, Wang Y, Zhao J, Dong Z, Lu D.   +11 more
europepmc   +1 more source

Oxidative Damage, Energy Imbalance, and Behavioral Disruptions in Girardia tigrina Exposed to Treated Sewage Effluents

Environmental Toxicology, EarlyView.
ABSTRACT This study assessed the ecotoxicological effects of treated sewage on the freshwater planarian Girardia tigrina, integrating biochemical, energetic, and behavioral biomarkers. Planarians were exposed for 48 h to different concentrations of treated sewage (12.5%, 25%, 50%, and 100%) and compared to controls using commercial water and water from
Renata M. P. Freitas, Pedro H. Carvalho, Daniela de Melo e Silva, Carlos Gravato   +3 more
wiley   +1 more source

Reciprocal regulation of cardiac β-oxidation and pyruvate dehydrogenase by insulin. [PDF]

J Biol Chem
Elnwasany A, Ewida HA, Menendez-Montes I, Mizerska M, Fu X, Kim CW, Horton JD, Burgess SC, Rothermel BA, Szweda PA, Szweda LI.   +10 more
europepmc   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Pyruvate Dehydrogenase Complex in Neonatal Hypoxic-Ischemic Brain Injury. [PDF]

ACS Pharmacol Transl Sci
Zhou T, Zhong Y, Zhang Y, Zhou Y.
europepmc   +1 more source

The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice. [PDF]

Hepatol Commun
Wu J, Huang E, McMullen MR, Singh V, Mrdjen M, Bellar A, Wang L, Welch N, Dasarathy J, Dasarathy S, Streem D, Brown JM, Nagy LE.   +12 more
europepmc   +1 more source

Deletion of pyruvate dehydrogenase kinases reduces susceptibility to deep vein thrombosis in mice. [PDF]

Blood Adv
Flora GD, Ghatge M, Nayak MK, Barbhuyan T, Kumskova M, Chauhan AK.   +5 more
europepmc   +1 more source

Manifestations of X-linked pyruvate dehydrogenase complex deficiency in female PDHA1 carriers. [PDF]

Eur J Neurol
Savvidou A, Sofou K, Eklund EA, Aronsson J, Darin N.   +4 more
europepmc   +1 more source

Next Generation AAV-F Capsid gene therapy rescues disease pathology in a model of Pyruvate Dehydrogenase Complex Deficiency

Keegan A, Cetin O, Chilcott EM, Antinao Diaz J, Eaton S, Waddington SN, Counsell JR, Rahman S, Karda R.   +8 more
europepmc   +1 more source

Corrigendum to: "Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis". [PDF]

Neuro Oncol
europepmc   +1 more source