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Pyruvate dehydrogenase deficiencies

1980
The extraordinary complexity of the pyruvate dehydrogenase complex (PDHC) is clearly documented in Chapter 12. PDHC contains three catalytic and two regulatory enzymes. It is subject to an intricate array of controls, including phosphorylation and dephosphorylation of the α-subunit of its thiamin-dependent component, end-product inhibition by NADH and ...
openaire   +1 more source

R-Lipoic Acid Inhibits Mammalian Pyruvate Dehydrogenase Kinase

Free Radical Research, 2004
Lioubov G Korotchkina, Mulchand S Patel
exaly  

Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases

Archives of Physiology and Biochemistry, 2006
Mary C Sugden, Mark J Holness
exaly  

Regulation of pyruvate dehydrogenase kinase and phosphatase by acetyl-CoA/CoA and NADH/NAD ratios

Biochemical and Biophysical Research Communications, 1975
Flora H Pettit   +2 more
exaly  

Binding of thiamin thiazolone pyrophosphate to mammalian pyruvate dehydrogenase and its effects on kinase and phosphatase activities

Biochemical and Biophysical Research Communications, 1977
Flora H Pettit, Lester J Reed, L J Reed
exaly  

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