Results 171 to 180 of about 158,743 (322)

Thiamine-responsive pyruvate dehydrogenase complex deficiency presenting as recurrent muscle weakness: Identification of a novel mutation (p.T111I) in the PDHA1 gene. [PDF]

Pediatr Int, 2023
Hayano S, Amamoto M, Naito E.
europepmc   +1 more source

The Pyruvate‐Dehydrogenase Complex from Azotobacter vinelandii [PDF]

, 1975
Hans J. Grande, Tjarda W. BRESTERS, Ronney A. De Abreu, Arie de KOK, C. Veeger   +4 more
openalex   +1 more source

Combining Electrochemical Reduction with Biosynthesis for Directed Conversion of CO2 into a Library of C3 Chemicals

Advanced Science, EarlyView.
In the H‐type electrolytic cell, carbon dioxide is reduced to acetic acid via electro‐microbial catalysis. The simply processed acetic acid is further converted through biological fermentation into high‐value‐added products, including acrylic acid, L‐lactic acid, and β‐alanine.
Kaixing Xiao, Shanquan Liang, Xujun Zhao, Zhiyao Peng, Ruoshi Luo, Jikai Zong, Ling Zhou, Yude Su, Dan Wang   +8 more
wiley   +1 more source

Pyruvate dehydrogenase complex (PDC) subunits moonlight as interaction partners of phosphorylated STAT5 in adipocytes and adipose tissue [PDF]

, 2017
Allison J. Richard, Hardy Hang, Jacqueline M. Stephens   +2 more
openalex   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Secretory S complex of Bacillus subtilis: sequence analysis and identity to pyruvate dehydrogenase

, 1990
Harri Hemilä, Airi Palva, Lars Paulín, Staffan Arvidson, Ilkka Palva   +4 more
openalex   +2 more sources

Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the αV138M variant of human pyruvate dehydrogenase [PDF]

, 2018
Matthew J. Whitley, Palaniappa Arjunan, Natalia S. Nemeria, Lioubov G. Korotchkina, Yun‐Hee Park, Mulchand S. Patel, Frank Jordan, William Furey   +7 more
openalex   +1 more source

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, EarlyView.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

Regulatory Properties of the Pyruvate-Dehydrogenase Complex from Escherichia coli. Thiamine Pyrophosphate as an Effector [PDF]

, 1974
Hans Bisswanger
openalex   +1 more source

Bioinformatics‐based discovery of the involvement of PSAT1 in mediating the anti‐lung adenocarcinoma activity of triptolide

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing was performed on tumor tissues from triptolide‐treated tumor‐bearing mice. The sequencing results were integrated with data from public databases for comprehensive analysis, and potential regulatory targets of triptolide were identified.
Zhiwen Cao, Lulu Zhang, Wenqiang Zhang, Rong Wan, Xiaogang Peng, Jinyan Xie, Ruru Bai, Jiejing Jin, Changqi Shi, Lan Yan, Xiangyu Guo, Yang Shen, Cheng Lu   +12 more
wiley   +1 more source