Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning. [PDF]
Bebarta VS, Nath AK.
europepmc +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal+3 more
wiley +1 more source
Hepatic bioenergetics and metabolism in mitochondrial disease: insights from the Ndufs4 KO mouse model. [PDF]
Terburgh K, Sweeney N, Louw R.
europepmc +1 more source
The Landscape of Cancer Metabolism as a Therapeutic Target
ABSTRACT Cancer cells reprogram their metabolism during progression to adapt to the tumor microenvironment, which is characterized by distinct differences in nutrient availability, oxygen concentrations, and acidity. This metabolic reprogramming can simultaneously create metabolic vulnerabilities unique to cancer cells, making cancer metabolism a ...
Kenji Ohshima
wiley +1 more source
New Targets for Immune Inflammatory Response in Rheumatoid Arthritis: Focus on the Potential Significance of N6-Methyladenosine, Ferroptosis and Cuproptosis. [PDF]
Wang S, Wan L, Zhang M, Yan D, Li F.
europepmc +1 more source
The effects of vitamin B in depression [PDF]
Apostolopoulos, Vasso+2 more
core +1 more source
The multifaceted roles of ketones in physiology
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili+3 more
wiley +1 more source
A missense mutation in PDHB gene: identification of the patient with pyruvate dehydrogenase deficiency and demonstration of pathogenicity in vitro. [PDF]
Li Y, Cheng L, Li X, Liu J, Yi L, Bo T.
europepmc +1 more source
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge+10 more
wiley +1 more source
The Clinical and Biochemical Impact of the Multivitamin Shortage on Neonatal Patients. [PDF]
Frankel R+3 more
europepmc +1 more source