Results 201 to 210 of about 80,914 (291)

Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity. [PDF]

Anim Nutr, 2022
Luo Y, Zhou W, Li R, Limbu SM, Qiao F, Chen L, Zhang M, Du ZY.   +7 more
europepmc   +1 more source

Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance

New Phytologist, EarlyView.
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap, Arash Fazeli, Ali Bandehagh, Nicolas L. Taylor   +3 more
wiley   +1 more source

Renometabolic disorder in experimental rat model of polycystic ovarian syndrome is reversed by acetate-mediated inhibition of pyruvate dehydrogenase kinase 4. [PDF]

BMC Nephrol
Areloegbe SE, Atuma CL, Aturamu A, Ajadi IO, Adelekan OE, Ajadi MB, Akintayo CO, Omoruyi GO, Onyekweli SO, Anifowose OF, Amusa OA, Ajayi K, Oyewole PA, Adegoke TE, Olaniyi KS.   +14 more
europepmc   +1 more source

Corrigendum to "Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis" [Liver Res. 2 (2018) 100-107]. [PDF]

Liver Res, 2023
Choiniere J, Lin MJ, Wang L, Wu J.
europepmc   +1 more source

Kinetic parameter prediction using neural networks identifies limitations to C4 photosynthesis

New Phytologist, EarlyView.
Schematic overview of the generation of artificial training data and training of neural networks in C4TUNE. Summary Kinetic models of photosynthesis enable time‐resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis.
Philipp Wendering, John Ferguson, Rudan Xu, Johannes Kromdijk, Zoran Nikoloski   +4 more
wiley   +1 more source

The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice. [PDF]

Hepatol Commun
Wu J, Huang E, McMullen MR, Singh V, Mrdjen M, Bellar A, Wang L, Welch N, Dasarathy J, Dasarathy S, Streem D, Brown JM, Nagy LE.   +12 more
europepmc   +1 more source

Hsa_circ_0000418 promotes the progression of glioma by regulating microRNA-409-3p / pyruvate dehydrogenase kinase 1 axis. [PDF]

Bioengineered, 2022
Ma Z, Chen Z, Zhou Y, Li Y, Li S, Wang H, Feng J.   +6 more
europepmc   +1 more source

DNA Methylation Shapes Seed‐Borne Microbiome and Proteome Responses During Early Maize‐Beneficial Bacteria Interactions

Plant, Cell &Environment, EarlyView.
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Pedro Igor Zocateli, Geovanna Vitória Olímpio, Felipe Astolpho de Almeida, Letícia Oliveira da Rocha, Diego Vinicius de Sena Martins, Sara Sangi, Fábio Lopes Olivares, Elyabe Monteiro de Matos, Juliana Siqueira, Lyderson Facio Viccini, Roberta Pena da Paschoa, Vanildo Silveira, Clícia Grativol   +12 more
wiley   +1 more source

Sodium Phenylbutyrate Attenuates Cisplatin-Induced Acute Kidney Injury Through Inhibition of Pyruvate Dehydrogenase Kinase 4. [PDF]

Biomedicines
Oh CJ, Choi W, Lee HY, Lee IK, Kim MJ, Jeon JH.   +5 more
europepmc   +1 more source

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, EarlyView.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source