Results 281 to 290 of about 168,834 (385)

Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells [PDF]

, 2014
Yuting Sun, Anneleen Daemen, Georgia Hatzivassiliou, David Arnott, Catherine Wilson, Guanglei Zhuang, Min Gao, Peter Liu, Aaron Boudreau, Leisa Johnson, Jeff Settleman   +10 more
openalex   +1 more source

Body size of male Atlantic salmon (Salmo salar L.) at introduction of a 5‐week LD12:12 winter signal influences their decision to mature early or smoltify

Journal of Fish Biology, EarlyView.
Abstract Sexual maturation of male Atlantic salmon post‐smolts (‘jacking’) is undesired in aquaculture and seems to occur due to the intensification in modern facilities. Maturation depends on internal and external factors (temperature, photoperiod, feed availability, energy levels, body size, genetic background) that act on the brain‐pituitary‐gonad ...
Enrique Pino‐Martinez, Kristine F. Staveland, Mitchell S. Fleming, Pablo Balseiro, Cindy Pedrosa, Sigurd O. Handeland   +5 more
wiley   +1 more source

Investigation of the role of Ras and other signaling kinases on the regulation of pyruvate dehydrogenase complex activity [PDF]

, 2014
Antonio Garcia-Trinidad, Nicky Whalley, Susan E. Critchlow   +2 more
openalex   +1 more source

Modulation of Sodium and Ammonia Transporters in the Context of Viral Gill Diseases in Common Carp (Cyprinus carpio)

Journal of Fish Diseases, EarlyView.
ABSTRACT Osmoregulation and ammonia removal are among key physiological processes that take place in gills and affect fish homeostasis and well‐being. These processes can be disrupted by numerous environmental factors, but also by viral infections, especially those leading to severe gill disorders.
Maria Zawisza, Muhammad Abdullah, Magdalena Marcinkowska, Marek Matras, Krzysztof Rakus, Mikolaj Adamek   +5 more
wiley   +1 more source

Interdomain communications in pyruvate dehydrogenase kinase 2

The FASEB Journal, 2007
Alla Klyuyeva, Alina Tuganova, Kirill M. Popov   +2 more
openaire   +1 more source

Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2

, 2008
Todd J. Green, Alexei Grigorian, Alla Klyuyeva, Alina Tuganova, Ming Luo, Kirill M. Popov   +5 more
openalex   +1 more source

Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach

Journal of Fish Diseases, EarlyView.
ABSTRACT Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV).
Francesca Riva, Lauren Elaine Black, Kim D. Thompson, Philippe Sourd, Andrei Bordeianu, Christopher C. Chadwick, Hooman Moghadam, Jorge Del‐Pozo, Janina Costa, Richard Burchmore, Nicola Brady, Lewis Moore, Suzanne McGill, Mark McLaughlin, Peter David Eckersall   +14 more
wiley   +1 more source

Reducing Oxidative Stress and Inflammation by Pyruvate Dehydrogenase Kinase 4 Inhibition Is Important in Prevention of Renal Ischemia-Reperfusion Injury in Diabetic Mice. [PDF]

Diabetes Metab J
Khang AR, Kim DH, Kim MJ, Oh CJ, Jeon JH, Choi SH, Lee IK.   +6 more
europepmc   +1 more source

Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target? [PDF]

, 2015
Wen Zhang, Shaolin Zhang, Xiaohui Hu, Kin Yip Tam   +3 more
openalex   +1 more source

Corticotropin‐releasing hormone receptor 1 mediates the enhanced locomotor activity and metabolic demands to an acute thermal stress in adult zebrafish

Journal of Neuroendocrinology, Volume 37, Issue 4, April 2025.
Abstract We recently showed that Crh‐Crhr1 signalling is essential for acute stress‐related locomotor activity in zebrafish larvae. However, the possibility that Crhr1 activation may also initiate the acute metabolic demands for stress coping was unexplored.
Zachary Shvartsburd, Mathilakath M. Vijayan   +1 more
wiley   +1 more source