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Muscle pyruvate oxidation following denervation and reinnervation
Muscle & Nerve, 1983AbstractMuscle pyruvate metabolism was studied in rats following sciatic nerve crush. Control studies showed high pyruvate dehydrogenase and lipoamide dehydrogenase enzyme activity in muscle with type 1 fiber predominance (soleus) and low activities in muscle with type 2 fiber predominance (extensor digitorum longus), whereas lactate dehydrogenase was ...
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Brain pyruvate oxidation in experimental thiamin-deficiency encephalopathy
Clinica Chimica Acta, 1996Pyrithiamine-induced thiamin deficiency has been used in rat as an experimental form of Wernicke-Korsakoff encephalopathy, a disease associated with chronic alcoholism. Although the main etiological factor is known to be the lack of thiamin, the biochemical mechanisms involved in the pathogenesis remain unclear.
P, Munujos +4 more
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Pyruvate oxidation in Charcot‐Marie‐Tooth disease
Neurology, 1979Significant differences were found in pyruvate oxidation of disrupted skin fibroblasts from patients with Charcot-Marie-Tooth disease (CMT) or neuromuscular disease controls and normal controls, but there was a similar oxidative defect in both disease groups. "Heritable heterogeneity in situ" and additional enzyme faults may explain the normal activity
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Methodology in evaluating pyruvate oxidation
Annals of Neurology, 1979P, Kark +2 more
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The oxidation of methylglyoxal by mammalian pyruvate dehydrogenase
Archives of Biochemistry and Biophysics, 1989Mammalian pyruvate dehydrogenase actively catalyzed the oxidation of methylglyoxal to acetyl-CoA. The reaction was fully enzymatic with an estimated Km of 1.89 mM. On the other hand, methylglyoxal was a competitive inhibitor of the enzyme for pyruvate, the Ki being in the 1 mM range. The reaction was inhibited in the presence of HgCl2.
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PYRUVATE OXIDATION IN DESULPHOVIBRIO DESULPHURICANS
Journal of Bacteriology, 1954openaire +2 more sources
Oxidation of Pyruvic-Oxime by Soil Organisms
Nature, 1950J H, QUASTEL +2 more
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Pyruvate oxidation in brain: Some dialysable components of the pyruvate oxidation system.
The Biochemical journal, 2006I, Banga, S, Ochoa, R A, Peters
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