NMR and Patch-Clamp Characterization of Yeast Mitochondrial Pyruvate Carrier Complexes [PDF]
Biomolecules, 2023 The mitochondrial pyruvate carrier (Mpc) plays an indispensable role in the transport of pyruvates across the mitochondrial inner membrane. Despite the two distinct homologous proteins, Mpc1 and Mpc2, were identified in 2012, there are still ...
Zhen Wang +8 more
doaj +2 more sources
Organocatalytic Packed-Bed Reactors for the Enantioselective Flow Synthesis of Quaternary Isotetronic Acids by Direct Aldol Reactions of Pyruvates [PDF]
MoleculesThe utilization of the homogeneous (S)-2-pyrrolidine-tetrazole organocatalyst (Ley catalyst) in the self-condensation of ethyl pyruvate and cross-aldol reactions of ethyl pyruvate donor with non-enolizable pyruvate acceptors, namely the sterically ...
Lorenzo Poletti +6 more
doaj +2 more sources
Selective Generation of Aldimine and Ketimine Tautomers of the Schiff Base Condensates of Amino Acids with Imidazole Aldehydes or of Imidazole Methanamines with Pyruvates—Isomeric Control with 2- vs. 4-Substituted Imidazoles [PDF]
MoleculesThe Schiff base condensation of 5-methyl-4-imidazole carboxaldehyde, 5Me4ImCHO, and the anion of an amino acid, H2N-CH(R)CO2− (R = -CH3, -CH(CH3)2 and -CH2CH(CH3)2), gives the aldimine tautomer, Im-CH=N-CH(R)CO2−, while that of 5-methylimidazole-4 ...
Greg Brewer +3 more
doaj +2 more sources
Ожирение и метаболизм, 2022 BACKGROUND: An increase with age in the blood glucose level of permanent residents of the Arctic region is a risk factor for metabolic changes, including diabetes mellitus (DM), the frequency and prevalence of which is often accompanied by an increase in
A. A. Bichkaev +2 more
doaj +1 more source
Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice. [PDF]
PLoS ONE, 2014 Previous investigations demonstrated that pyruvate protects human keratinocytes against cell damage stemming from exposure to ultraviolet B (UVB) radiation.
Reiji Aoki +3 more
doaj +1 more source
Frontiers in Veterinary Science, 2021 Acute ruminal acidosis (ARA) occurs after an excessive intake of rapidly fermentable carbohydrates and is characterized by the overproduction of D-lactate in the rumen that reaches the bloodstream.
John Quiroga +14 more
doaj +1 more source
Adenosine Triphosphate and Carbon Efficient Route to Second Generation Biofuel Isopentanol. [PDF]
, 2020 Climate change necessitates the development of CO2 neutral or negative routes to chemicals currently produced from fossil carbon. In this paper we demonstrate a pathway from the renewable resource glucose to next generation biofuel isopentanol by pairing
Chiniquy, Jennifer +9 more
core +1 more source
Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection [PDF]
, 2006 Dioxiranes generated in situ from pyruvates (α-keto esters) and Oxone have been found to be environmentally friendly oxidizing agents for disinfection.
Chan, TC +6 more
core +1 more source
Archives of Clinical and Experimental Surgery, 2013 Objective: To study the splanchnic metabolism and intestinal circulation in a porcine model with increased abdominal pressure. Methods: In an experimental porcine study, performed under intravenous anaesthesia, five animals were subjected to gradually ...
Per Skoog +4 more
doaj +1 more source
Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle [PDF]
, 2015 Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production.
CAPUANI, FABRIZIO +3 more
core +3 more sources