Results 1 to 10 of about 23,768 (211)

NMR and Patch-Clamp Characterization of Yeast Mitochondrial Pyruvate Carrier Complexes [PDF]

open access: yesBiomolecules, 2023
The mitochondrial pyruvate carrier (Mpc) plays an indispensable role in the transport of pyruvates across the mitochondrial inner membrane. Despite the two distinct homologous proteins, Mpc1 and Mpc2, were identified in 2012, there are still ...
Zhen Wang   +8 more
doaj   +2 more sources

Organocatalytic Packed-Bed Reactors for the Enantioselective Flow Synthesis of Quaternary Isotetronic Acids by Direct Aldol Reactions of Pyruvates [PDF]

open access: yesMolecules
The utilization of the homogeneous (S)-2-pyrrolidine-tetrazole organocatalyst (Ley catalyst) in the self-condensation of ethyl pyruvate and cross-aldol reactions of ethyl pyruvate donor with non-enolizable pyruvate acceptors, namely the sterically ...
Lorenzo Poletti   +6 more
doaj   +2 more sources

Selective Generation of Aldimine and Ketimine Tautomers of the Schiff Base Condensates of Amino Acids with Imidazole Aldehydes or of Imidazole Methanamines with Pyruvates—Isomeric Control with 2- vs. 4-Substituted Imidazoles [PDF]

open access: yesMolecules
The Schiff base condensation of 5-methyl-4-imidazole carboxaldehyde, 5Me4ImCHO, and the anion of an amino acid, H2N-CH(R)CO2− (R = -CH3, -CH(CH3)2 and -CH2CH(CH3)2), gives the aldimine tautomer, Im-CH=N-CH(R)CO2−, while that of 5-methylimidazole-4 ...
Greg Brewer   +3 more
doaj   +2 more sources

Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age

open access: yesОжирение и метаболизм, 2022
BACKGROUND: An increase with age in the blood glucose level of permanent residents of the Arctic region is a risk factor for metabolic changes, including diabetes mellitus (DM), the frequency and prevalence of which is often accompanied by an increase in
A. A. Bichkaev   +2 more
doaj   +1 more source

Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice. [PDF]

open access: yesPLoS ONE, 2014
Previous investigations demonstrated that pyruvate protects human keratinocytes against cell damage stemming from exposure to ultraviolet B (UVB) radiation.
Reiji Aoki   +3 more
doaj   +1 more source

Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity

open access: yesFrontiers in Veterinary Science, 2021
Acute ruminal acidosis (ARA) occurs after an excessive intake of rapidly fermentable carbohydrates and is characterized by the overproduction of D-lactate in the rumen that reaches the bloodstream.
John Quiroga   +14 more
doaj   +1 more source

Intra-Abdominal Metabolism and Blood Flow During Abdominal Hypertension and ndash; A Porcine Pilot Study Under Intravenous Anaesthesia

open access: yesArchives of Clinical and Experimental Surgery, 2013
Objective: To study the splanchnic metabolism and intestinal circulation in a porcine model with increased abdominal pressure. Methods: In an experimental porcine study, performed under intravenous anaesthesia, five animals were subjected to gradually ...
Per Skoog   +4 more
doaj   +1 more source

Alkylation of Ethyl Pyruvate via Reductive Coupling of Alkenes and Ethyl 2-(Benzenesulfonylamino)acrylate

open access: yesCHIMIA, 2005
Radical coupling of B-alkylcatecholboranes, in situ generated from the corresponding alkenes, with ethyl 2-(benzenesulfonylamino)acrylate is reported.
Vincent Darmency, Philippe Renaud
doaj   +1 more source

Lactate oxidation at the mitochondria: a lactate-malate-aspartate shuttle at work

open access: yesFrontiers in Neuroscience, 2014
Lactate, the conjugate base of lactic acid occurring in aqueous biological fluids, has been derided as a dead-end waste product of anaerobic metabolism.
Daniel A Kane
doaj   +1 more source

Synthesis, characterization and thermal behaviour on solid pyruvates of light trivalent lanthanides

open access: yesEclética Química, 2018
Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La – Gd) and L is pyruvate, have been synthesized. Thermogravimetry and derivative thermo- gravimetry (TG/DTG), differential scanning calorimetry (DSC), X-Ray powder ...
A. B. Siqueira   +5 more
doaj   +1 more source

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