Results 1 to 10 of about 95,251 (345)

NMR and Patch-Clamp Characterization of Yeast Mitochondrial Pyruvate Carrier Complexes [PDF]

Biomolecules, 2023
The mitochondrial pyruvate carrier (Mpc) plays an indispensable role in the transport of pyruvates across the mitochondrial inner membrane. Despite the two distinct homologous proteins, Mpc1 and Mpc2, were identified in 2012, there are still ...
Zhen Wang, Wen Ding, Maosen Ruan, Yong Liu, Jing Yang, Huiqin Zhang, Bing Shen, Junfeng Wang, Yunyan Li   +8 more
doaj   +2 more sources

Organocatalytic Packed-Bed Reactors for the Enantioselective Flow Synthesis of Quaternary Isotetronic Acids by Direct Aldol Reactions of Pyruvates [PDF]

Molecules
The utilization of the homogeneous (S)-2-pyrrolidine-tetrazole organocatalyst (Ley catalyst) in the self-condensation of ethyl pyruvate and cross-aldol reactions of ethyl pyruvate donor with non-enolizable pyruvate acceptors, namely the sterically ...
Lorenzo Poletti, Carmela De Risi, Daniele Ragno, Graziano Di Carmine, Riccardo Tassoni, Alessandro Massi, Paolo Dambruoso   +6 more
doaj   +2 more sources

Copper-catalyzed asymmetric methylation of fluoroalkylated pyruvates with dimethylzinc

Beilstein Journal of Organic Chemistry, 2018
The catalytic asymmetric methylation of fluoroalkylated pyruvates is shown with dimethylzinc as a methylating reagent in the presence of a copper catalyst bearing a chiral phosphine ligand. This is the first catalytic asymmetric methylation to synthesize
Kohsuke Aikawa, Kohei Yabuuchi, Kota Torii, Koichi Mikami   +3 more
doaj   +2 more sources

Synthesis of Unsaturated Precursors for Parahydrogen-Induced Polarization and Molecular Imaging of 1-13C‑Acetates and 1-13C‑Pyruvates via Side Arm Hydrogenation

ACS Omega, 2018
Hyperpolarized forms of 1-13C-acetates and 1-13C-pyruvates are used as diagnostic contrast agents for molecular imaging of many diseases and disorders.
Nikita V. Chukanov, Oleg G. Salnikov, Roman V. Shchepin, Kirill V. Kovtunov, Igor V. Koptyug, Eduard Y. Chekmenev   +5 more
doaj   +2 more sources

Selective Generation of Aldimine and Ketimine Tautomers of the Schiff Base Condensates of Amino Acids with Imidazole Aldehydes or of Imidazole Methanamines with Pyruvates—Isomeric Control with 2- vs. 4-Substituted Imidazoles [PDF]

Molecules
The Schiff base condensation of 5-methyl-4-imidazole carboxaldehyde, 5Me4ImCHO, and the anion of an amino acid, H2N-CH(R)CO2− (R = -CH3, -CH(CH3)2 and -CH2CH(CH3)2), gives the aldimine tautomer, Im-CH=N-CH(R)CO2−, while that of 5-methylimidazole-4 ...
Greg Brewer, Cynthia Brewer, Raymond J. Butcher, Peter Zavalij   +3 more
doaj   +2 more sources

Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice. [PDF]

PLoS ONE, 2014
Previous investigations demonstrated that pyruvate protects human keratinocytes against cell damage stemming from exposure to ultraviolet B (UVB) radiation.
Reiji Aoki, Ayako Aoki-Yoshida, Chise Suzuki, Yoshiharu Takayama   +3 more
doaj   +2 more sources

Control of Reactions of Pyruvates by Catalysts: Direct Enantioselective Mannich Reactions of Pyruvates Catalyzed by Amine-based Catalyst Systems.

Organic Letters, 2022
Enantioselective Mannich reactions of pyruvates catalyzed by amine-based catalyst systems, in which pyruvates act as nucleophiles, are reported. The reactions of pyruvates and cyclic sulfonylimines afforded the desired Mannich products, including those ...
Santa Mondal, Ravindra D Aher, Venkati Bethi, Yu Lin, T. Taniguchi, K. Monde, F. Tanaka   +6 more
semanticscholar   +1 more source

Gender characteristics of the parameters of carbohydrate metabolism and pancreatic hormones in permanent residents of the Arctic region, taking into account age

Ожирение и метаболизм, 2022
BACKGROUND: An increase with age in the blood glucose level of permanent residents of the Arctic region is a risk factor for metabolic changes, including diabetes mellitus (DM), the frequency and prevalence of which is often accompanied by an increase in
A. A. Bichkaev, N. I. Volkova, F. A. Bichkaeva   +2 more
doaj   +1 more source

Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity

Frontiers in Veterinary Science, 2021
Acute ruminal acidosis (ARA) occurs after an excessive intake of rapidly fermentable carbohydrates and is characterized by the overproduction of D-lactate in the rumen that reaches the bloodstream.
John Quiroga, John Quiroga, Pablo Alarcón, Pablo Alarcón, Carolina Manosalva, Stefanie Teuber, Stefanie Teuber, Anja Taubert, Carlos Hermosilla, María Angélica Hidalgo, María Angélica Hidalgo, María Daniella Carretta, María Daniella Carretta, Rafael Agustín Burgos, Rafael Agustín Burgos   +14 more
doaj   +1 more source

Ruthenium-Catalyzed Diastereoselective Synthesis of Fully Substituted Pyrrolidines from Anilines and Diazo Pyruvates.

Organic Letters, 2020
An unprecedented synthesis of polysubstituted pyrrolidines from anilines and diazo pyruvates by ruthenium catalysis under mild reaction conditions is reported.
Farrukh Sajjad, Alavala Gopi Krishna Reddy, Jiuwei Che, Wenhao Hu, D. Xing   +4 more
semanticscholar   +1 more source