Copper-catalyzed asymmetric methylation of fluoroalkylated pyruvates with dimethylzinc
Beilstein Journal of Organic Chemistry, 2018 The catalytic asymmetric methylation of fluoroalkylated pyruvates is shown with dimethylzinc as a methylating reagent in the presence of a copper catalyst bearing a chiral phosphine ligand. This is the first catalytic asymmetric methylation to synthesize
Kohsuke Aikawa +3 more
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Synthesis of 4-Substituted-Pyridine-2,6-dicarboxylic Acid Derivatives from Pyruvates and Aldehydes in One Pot [PDF]
, 2017 4-Substituted-pyridine-2,6-dicarboxylic acid derivatives were synthesized in one pot under mild conditions via the formation of dihydropyran derivatives from pyruvates and aldehydes catalyzed by pyrrolidine-acetic acid, followed by the reaction with ...
Lapointe, Sébastien +2 more
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The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier [PDF]
Biomolecules, 2020 Pyruvate, the end product of glycolysis, plays a major role in cell metabolism. Produced in the cytosol, it is oxidized in the mitochondria where it fuels the citric acid cycle and boosts oxidative phosphorylation. Its sole entry point into mitochondria is through the recently identified mitochondrial pyruvate carrier (MPC).
Zangari J +3 more
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OBO-protected pyruvates as reagents for the synthesis of functionalized heteroaromatic compounds [PDF]
, 2018 Pd-catalyzed α-arylation of methyl-OBO-ketone (OBO = 4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl) gives rise to arylated OBO-protected pyruvates. By appropriate prefunctionalization of the aryl ring or by subsequent functionalization at the α-carbonyl ...
C. Henrique Alves Esteves +9 more
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, 2016 An efficient enantioselective approach to chiral dihydropyrones has been developed by the hetero-Diels−Alder (HDA) reactions of (E)-4-methoxy-2-trimethylsiloxy-penta-1,3-diene (diene 1) with aldehydes and pyruvates.
Ying Du (42066) +4 more
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Photochemistry of alkyl pyruvates [PDF]
, 1986 The photochemistry of alkyl pyruvates of the type CH3COCOOCHR2 has been examined in solution using a combination of product studies and laser flash photolysis techniques.
Encinas, M. V. +4 more
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The relationships between transketolase, yeast pyruvate decarboxylase and pyruvate dehydrogenase of the pyruvate dehydrogenase complex [PDF]
FEBS Letters, 1993 The amino acid sequences of four thiamine pyrophosphate‐requiring enzymes were aligned with the published amino acid sequence of the transketolase of Hansenula polymorpha. Sequences of the combined α and β subunits of the E1 enzyme of the pyruvate dehydrogenase complexes of Homo sapiens and Bacillus stearothermophilus aligned well with the ...
Robinson, Brian H., Chun, Kathy
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ANTICANCER POTENTIAL OF NOVEL PALLADIUM(II) COMPLEXES WITH ACYL PYRUVATES AS LIGANDS: DNA AND BSA INTERACTIONS AND MOLECULAR DOCKING STUDY [PDF]
STED JournalBearing in mind that some palladium complexes showed good antitumor potential while exhibiting less kidney toxicity comparing to cisplatin, to discover a new agents for chemotherapy with improved properties two novel palladium(II) complexes [Pd (L)2] (3A
Nenad Joksimović +4 more
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Evening chronotype is associated with higher circulating pyruvate levels in adults
Frontiers in NutritionBackground/objectivesChronotype reflects interindividual differences in the circadian timing system. Animal studies suggest reduced mitochondrial oxidative metabolism and tricarboxylic acid (TCA) cycle activity in individuals with an evening chronotype ...
Sarang Jeong +6 more
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Development of Catalytic Asymmetric Reactions of Pyruvates as Nucleophiles [PDF]
Okinawa Institute of Science and Technology Graduate UniversityDoctor of PhilosophyPyruvates or α-ketoesters, are important molecules in both organic chemistry and biology due to their intrinsic reactivity. Pyruvates can act as nucleophiles (reactions as
Mondal, Santanu
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