Results 11 to 20 of about 2,702 (229)

The relationships between transketolase, yeast pyruvate decarboxylase and pyruvate dehydrogenase of the pyruvate dehydrogenase complex [PDF]

FEBS Letters, 1993
The amino acid sequences of four thiamine pyrophosphate‐requiring enzymes were aligned with the published amino acid sequence of the transketolase of Hansenula polymorpha. Sequences of the combined α and β subunits of the E1 enzyme of the pyruvate dehydrogenase complexes of Homo sapiens and Bacillus stearothermophilus aligned well with the ...
Robinson, Brian H., Chun, Kathy
openaire   +2 more sources

Synthesis, characterization and thermal behaviour on solid pyruvates of light trivalent lanthanides

Eclética Química, 2018
Solid State Ln-L compounds, where Ln stands for light trivalent lanthanides (La – Gd) and L is pyruvate, have been synthesized. Thermogravimetry and derivative thermo- gravimetry (TG/DTG), differential scanning calorimetry (DSC), X-Ray powder ...
A. B. Siqueira, C. T. de Carvalho, Érica Alvarenga Crespo Rodrigues, Elias Y. Ionashiro, Gilbert Bannach, Massao Ionashiro   +5 more
doaj   +1 more source

Copper-catalyzed asymmetric methylation of fluoroalkylated pyruvates with dimethylzinc

Beilstein Journal of Organic Chemistry, 2018
The catalytic asymmetric methylation of fluoroalkylated pyruvates is shown with dimethylzinc as a methylating reagent in the presence of a copper catalyst bearing a chiral phosphine ligand. This is the first catalytic asymmetric methylation to synthesize
Kohsuke Aikawa, Kohei Yabuuchi, Kota Torii, Koichi Mikami   +3 more
doaj   +1 more source

Synthesis, characterization and thermal behaviour on solid pyruvates of some bivalent metal ions.

Eclética Química, 2018
Solid state M-L compounds, were M stands for bivalent Mn, Fe, Co, Ni, Cu, Zn and L is pyruvate, have been synthesized. Thermogravimetry and derivative thermogravimetry (TG/DTG), differential scanning calorimetry (DSC), X-Ray powder diffractometry ...
Adriano Buzutti de Siqueira, Cláudio Teodoro de Carvalho, Elias Yuki Ionashiro, Massao Ionashiro   +3 more
doaj   +1 more source

ANTICANCER POTENTIAL OF NOVEL PALLADIUM(II) COMPLEXES WITH ACYL PYRUVATES AS LIGANDS: DNA AND BSA INTERACTIONS AND MOLECULAR DOCKING STUDY [PDF]

STED Journal
Bearing in mind that some palladium complexes showed good antitumor potential while exhibiting less kidney toxicity comparing to cisplatin, to discover a new agents for chemotherapy with improved properties two novel palladium(II) complexes [Pd (L)2] (3A
Nenad Joksimović, Jelena Petronijević, Marina Serafinović, Nenad Janković, Dejan Baskic   +4 more
doaj   +1 more source

Evening chronotype is associated with higher circulating pyruvate levels in adults

Frontiers in Nutrition
Background/objectivesChronotype reflects interindividual differences in the circadian timing system. Animal studies suggest reduced mitochondrial oxidative metabolism and tricarboxylic acid (TCA) cycle activity in individuals with an evening chronotype ...
Sarang Jeong, Sarang Jeong, Eunjin Jang, Jinhyun Kim, Sang Youl Rhee, Sohyun Park, Sohyun Park   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source