NMR and Patch-Clamp Characterization of Yeast Mitochondrial Pyruvate Carrier Complexes [PDF]
Biomolecules, 2023 The mitochondrial pyruvate carrier (Mpc) plays an indispensable role in the transport of pyruvates across the mitochondrial inner membrane. Despite the two distinct homologous proteins, Mpc1 and Mpc2, were identified in 2012, there are still ...
Zhen Wang +8 more
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Organocatalytic Packed-Bed Reactors for the Enantioselective Flow Synthesis of Quaternary Isotetronic Acids by Direct Aldol Reactions of Pyruvates [PDF]
MoleculesThe utilization of the homogeneous (S)-2-pyrrolidine-tetrazole organocatalyst (Ley catalyst) in the self-condensation of ethyl pyruvate and cross-aldol reactions of ethyl pyruvate donor with non-enolizable pyruvate acceptors, namely the sterically ...
Lorenzo Poletti +6 more
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Selective Generation of Aldimine and Ketimine Tautomers of the Schiff Base Condensates of Amino Acids with Imidazole Aldehydes or of Imidazole Methanamines with Pyruvates—Isomeric Control with 2- vs. 4-Substituted Imidazoles [PDF]
MoleculesThe Schiff base condensation of 5-methyl-4-imidazole carboxaldehyde, 5Me4ImCHO, and the anion of an amino acid, H2N-CH(R)CO2− (R = -CH3, -CH(CH3)2 and -CH2CH(CH3)2), gives the aldimine tautomer, Im-CH=N-CH(R)CO2−, while that of 5-methylimidazole-4 ...
Greg Brewer +3 more
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Ожирение и метаболизм, 2022 BACKGROUND: An increase with age in the blood glucose level of permanent residents of the Arctic region is a risk factor for metabolic changes, including diabetes mellitus (DM), the frequency and prevalence of which is often accompanied by an increase in
A. A. Bichkaev +2 more
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Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice. [PDF]
PLoS ONE, 2014 Previous investigations demonstrated that pyruvate protects human keratinocytes against cell damage stemming from exposure to ultraviolet B (UVB) radiation.
Reiji Aoki +3 more
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Frontiers in Veterinary Science, 2021 Acute ruminal acidosis (ARA) occurs after an excessive intake of rapidly fermentable carbohydrates and is characterized by the overproduction of D-lactate in the rumen that reaches the bloodstream.
John Quiroga +14 more
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The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier [PDF]
Biomolecules, 2020 Pyruvate, the end product of glycolysis, plays a major role in cell metabolism. Produced in the cytosol, it is oxidized in the mitochondria where it fuels the citric acid cycle and boosts oxidative phosphorylation. Its sole entry point into mitochondria is through the recently identified mitochondrial pyruvate carrier (MPC).
Zangari J +3 more
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Archives of Clinical and Experimental Surgery, 2013 Objective: To study the splanchnic metabolism and intestinal circulation in a porcine model with increased abdominal pressure. Methods: In an experimental porcine study, performed under intravenous anaesthesia, five animals were subjected to gradually ...
Per Skoog +4 more
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CHIMIA, 2005 Radical coupling of B-alkylcatecholboranes, in situ generated from the corresponding alkenes, with ethyl 2-(benzenesulfonylamino)acrylate is reported.
Vincent Darmency, Philippe Renaud
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The relationships between transketolase, yeast pyruvate decarboxylase and pyruvate dehydrogenase of the pyruvate dehydrogenase complex [PDF]
FEBS Letters, 1993 The amino acid sequences of four thiamine pyrophosphate‐requiring enzymes were aligned with the published amino acid sequence of the transketolase of Hansenula polymorpha. Sequences of the combined α and β subunits of the E1 enzyme of the pyruvate dehydrogenase complexes of Homo sapiens and Bacillus stearothermophilus aligned well with the ...
Robinson, Brian H., Chun, Kathy
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