Results 111 to 120 of about 95,354 (345)
THE PYRUVATE OXIDATION FACTOR REQUIREMENT OF STREPTOCOCCUS CREMORIS [PDF]
V. L. Lytle, Dennis J. O’Kane
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This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu+13 more
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Partial purification and properties of (S)-norlaudanosoline synthase from Eschscholtzia tenuifolia cell cultures [PDF]
Nagakura, Naotaka+3 more
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The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang+16 more
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Decarboxylation of Pyruvate by Thiamine Analogues
Ralph G. Yount, David E. Metzler
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The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou+11 more
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CONVERSION OF ACETATE AND PYRUVATE TO ASPARTIC ACID IN YEAST
Chih H. Wang+3 more
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Distant precursors of benzylisoquinoline alkaloids and their enzymatic formation [PDF]
Rüffer, Martina, Zenk, Meinhart H.
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