Results 81 to 90 of about 27,119 (206)

Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment

Aging Cell, Volume 25, Issue 5, May 2026.
In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula, Anjaly KM, Faraz Rashid, Mohammad Nematullah, Harshit Singh, Tanya Bhardwaj, Miriana Hijaz, Shailendra Giri, Eduardo N. Chini, Heather M. Gibson, Ramandeep Rattan   +10 more
wiley   +1 more source

Efficacy and mechanism of energy metabolism dual-regulated nanoparticles (atovaquone-albendazole nanoparticles) against cystic echinococcosis

BMC Infectious Diseases
Background Albendazole (ABZ) and atovaquone (ATO) achieve killing efficacy on Echinococcus granulosus (Egs) by inhibiting energy metabolism, but their utilization rate is low.
Yuehong Gong, Tianjiao Zhou, Ruijia Ma, Jianhua Yang, Yicong Zhao, Meichi Pan, Zhangjian Huang, Hao Wen, Hulin Jiang, Jianhua Wang   +9 more
doaj   +1 more source

A Split Face Comparative Study to Evaluate the Efficacy of 40% Pyruvic Acid vs. Microdermabrasion with 40% Pyruvic Acid on Biomechanical Skin Parameters in the Treatment of Acne Vulgaris. [PDF]

J Clin Med, 2022
Rusztowicz M, Chilicka K, Szyguła R, Odrzywołek W, Yanakieva A, Asanova B, Wilczyński S.   +6 more
europepmc   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, Volume 183, Issue 9, Page 2099-2122, May 2026.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Distribution of nutritive compounds and sensory quality in the leafs of chives (Allium schoenoprasum L.)

Journal of Applied Botany and Food Quality, 2012
The distribution of sulphur, thio-sulphinates (pyruvic acid method), SSC, colour, fresh- and dry matter was analysed in three sections, base, centre, and tip, along the leaf tube of chives.
B. Brueckner, H. Perner
doaj  

Indole-3-pyruvic acid alleviates rheumatoid arthritis via the aryl hydrocarbon receptor pathway. [PDF]

Ann Transl Med, 2023
Huang T, Cheng L, Jiang Y, Zhang L, Qian L.   +4 more
europepmc   +1 more source

Antisense reduction in NADP‐ME in the C4 species Flaveria bidentis alters stomatal sensitivity to intercellular [CO2]

New Phytologist, Volume 250, Issue 3, Page 1585-1597, May 2026.
Summary Stomata have the crucial role of balancing the uptake of CO2 for photosynthesis and water loss via transpiration by adjusting their aperture. In C3 plants, coordination between photosynthesis and stomatal conductance can be disrupted by mutations in Calvin–Benson–Bassham (CBB) cycle expression, but it is not clear whether the disruption of the ...
Emmanuel L. Bernardo, Cristina Rodrigues Gabriel Sales, Tianshu Sun, Johannes Kromdijk   +3 more
wiley   +1 more source

Radical-Induced Low-Field ¹H Relaxation in Solid Pyruvic Acid Doped with Trityl-OX063. [PDF]

J Phys Chem Lett, 2022
Jurkutat M, Kouřilová H, Peat D, Kouřil K, Khan AS, Horsewill AJ, MacDonald JF, Owers-Bradley J, Meier B.   +8 more
europepmc   +1 more source

Beneficial rhizobacteria and virus infection modulate the soybean metabolome and influence the feeding preferences of the virus vector Epilachna varivestis

New Phytologist, Volume 250, Issue 4, Page 2599-2618, May 2026.
Summary Beneficial rhizobacteria and viral pathogens can both alter host plant phenotypes, yet little is known about how their simultaneous presence influences plant metabolism and species interactions. We investigated how two rhizobacteria, Bradyrhizobium japonicum and Delftia acidovorans, together with bean pod mottle virus (BPMV), shape soybean ...
Hannier Pulido, Kerry E. Mauck, Consuelo M. De Moraes, Mark C. Mescher   +3 more
wiley   +1 more source

The miR319/bHLH094 Module Regulates Creeping Bentgrass Thermotolerance by Modulating Auxin Biosynthesis and Signalling Pathway

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3201-3218, May 2026.
ABSTRACT MicroRNA319 (miR319) has been demonstrated to regulate plant development and responses to stress such as drought and salt. However, its role in thermotolerance, particularly in cool season grasses, remains unclear. Here we report that miR319 plays a negative role in heat tolerance of creeping bentgrass (Agrostis stolonifera).
Kangting Dong, Chang Liu, Mingyue Wang, Dayong Li, Jialin Li, Ning Zhao, Jianmiao Sun, Xiaodong Wang, Hongjie Di, Hong Luo, Xinbo Sun   +10 more
wiley   +1 more source