Results 41 to 50 of about 3,013,991 (279)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Relationships between Near-Surface Horizontal Dust Fluxes and Dust Depositions at the Centre and Edge of the Taklamakan Desert

open access: yesLand, 2022
The emission, transport, and deposition of dust are frequently the focus of dust aerosol studies. However, owing to limited observation data, few studies have examined the relationships between the key parameters of dust transport, especially in typical ...
Wen Huo   +9 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Airborne observations of newly formed boundary layer aerosol particles under cloudy conditions [PDF]

open access: yesAtmospheric Chemistry and Physics, 2018
This study describes the appearance of ultrafine boundary layer aerosol particles under classical non-favourable conditions at the research site of TROPOS (Leibniz Institute for Tropospheric Research).
B. Altstädter   +11 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Particulate trimethylamine in the summertime Canadian high Arctic lower troposphere [PDF]

open access: yesAtmospheric Chemistry and Physics, 2017
Size-resolved and vertical profile measurements of single particle chemical composition (sampling altitude range 50–3000 m) were conducted in July 2014 in the Canadian high Arctic during an aircraft-based measurement campaign (NETCARE 2014).
F. Köllner   +16 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Particle acceleration near a rotating charged black hole in 4D Einstein-Gauss-Bonnet gravity

open access: yesNuclear Physics B
We investigate the horizon structure and ergosphere in a charged rotating black hole within 4D Einstein-Gauss-Bonnet gravity, which introduces additional parameters (Q) because of the charge and Gauss-Bonnet parameter (β), besides the mass (M) and ...
Abdurakhmon Nosirov   +4 more
doaj   +1 more source

The theory of early nonlinear stage of m=1 instability with locally flattened q-profile

open access: yesMatter and Radiation at Extremes, 2018
In this paper, we analyze the modification of fast particles on the nonlinear radial displacement of m = 1 internal kink mode with a shoulder-like equilibrium current theoretically.
Kai-Qi Cao, Xian-Qu Wang
doaj   +1 more source

Two-Q-boson interferometry and generalization of the Wigner function

open access: yes, 2004
Bose-Einstein correlations of two identically charged Q-bosons are derived considering those particles to be confined in finite volumes. Boundary effects on single Q-boson spectrum are also studied.
Zhang, Q. H., Padula, Sandra S.
core   +1 more source

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