Results 111 to 120 of about 936,931 (309)

Combined Mass Spectrometry-Based Metabolite Profiling of Different Pigmented Rice (Oryza sativa L.) Seeds and Correlation with Antioxidant Activities

Molecules, 2014
Nine varieties of pigmented rice (Oryza sativa L.) seeds that were black, red, or white were used to perform metabolite profiling by using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF-MS) and gas ...
Ga Ryun Kim, Eun Sung Jung, Sarah Lee, Sun-Hyung Lim, Sun-Hwa Ha, Choong Hwan Lee   +5 more
doaj   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Additional file 5 of Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS

, 2022
Additional file 5: Table S1.
Na Lin (69470), Ruoyao Shi (8629455), Yan He (116705), Hao Wu (65943), Tao Li (86810), Hongliang Yao (1748278), Weijie Li (139178), Yanqiong Zhang (212683), Zhenkun Zhou (11599590), Linlin Jin (8489181)   +9 more
core   +1 more source

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

Metabolic Profiling of Liver Tissue Based on UPLC Q-TOF/MS

, 2010
Metabolic Profiling of Liver Tissue Based on UPLC Q-TOF ...
许国旺, 黄强
core  

Table3_Exploring potential mechanism of ciwujia tablets for insomnia by UPLC-Q-TOF-MS/MS, network pharmacology, and experimental validation.XLSX

, 2022
Insomnia, whether chronic or intermittent, is a common central nervous system disease. Ciwujia Tablet (CWT) is a well-known traditional Chinese medicine (TCM) made from the extract of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim.
Le Yang (345935), Hui Sun (107933), Xijun Wang (413258), Hongda Liu (6702581), Guangli Yan (413257), Zhineng Li (412763), Chunlei Wan (1510855), Ying Han (137520)   +7 more
core   +1 more source

Exploring the mechanisms underlying the differences in the “warming the middle to dispel cold” effects of dried and baked ginger based on UPLC-Q-TOF-MS/MS combined with network pharmacology [PDF]

Shandong kexue
Ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS/MS) was used to analyze the differences in chemical composition of dried and baked ginger.Then, network pharmacology was applied to ...
LI Junxian, LIU Shuang, MI Yuzhang, LU Tengfei, WANG Xiao, DONG Hongjing, LIU Ziyao
doaj   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Optimization of extraction for diterpenoids from Euphorbia fischeriana Steud using response surface methodology and structure identification by UPLC-Q-TOF-MS

, 2019
Jolkinolide A, jolkinolide B, 17-hydroxyjolkinolide A and 17-hydroxyjolkinolide B are abundant constitutes in Euphorbia Fischeriana Steud and exhibit profound bioactivities.
Tiancheng Ma (7511672), Yu Sun (18463), Yukun Ma (7511675), Jia Sun (761745), Lina Guo (706104), Qi Liu (33068), Lei Liu (5074)   +6 more
core   +1 more source

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source