Results 231 to 240 of about 144,159 (273)

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

In Vivo Functional and Structural Retinal Preservation by Combined Administration of Citicoline and Coenzyme Q10 in a Murine Model of Ocular Hypertension. [PDF]

Int J Mol Sci
Matamoros JA, Salobrar-García E, Salazar JJ, López-Cuenca I, Elvira-Hurtado L, Martínez MA, Rubio-Casado S, Paleo-García V, Hoz R, Ramírez JM, de la Villa P, Fernández-Albarral JA, Ramirez AI.   +12 more
europepmc   +1 more source

Genome‐Wide Association Studies for 24 Hematological Traits in Production Pigs Before and After Weaning

Animal Genetics, Volume 57, Issue 2, April 2026.
ABSTRACT Hematological traits are essential indicators of an animal's immune status and overall health, reflecting both physiological and pathological conditions. The complete blood count (CBC), a commonly used clinical test, evaluates the concentrations, proportions, and characteristics of various blood cell parameters, providing insights into an ...
Jiahong Sun, Emil Ibragimov, Malene Kjelin Morsing, Martin Peter Rydal, Lise Nikolic Nielsen, Zexi Cai, Jens Peter Nielsen, Merete Fredholm, Peter Karlskov‐Mortensen   +8 more
wiley   +1 more source

Reversing Acute Cardiomyopathy With Coenzyme Q10 Supplementation in Cobalamin B Disease: A Case Report and Literature Review. [PDF]

JIMD Rep
Said D, Al Shamsi A.
europepmc   +1 more source

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

Decades of Misdiagnosis as Myasthenia Gravis: Late‐Onset POLG‐Related Ophthalmoplegia Unveiled by Whole‐Genome Sequencing

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT A 55‐year‐old male developed POLG‐related ophthalmoplegia in 2015 and was misdiagnosed with seronegative myasthenia gravis for 10 years. Whole‐genome sequencing identified compound heterozygous POLG mutations, highlighting its value in diagnosing refractory neuromuscular disorders.
Tanli Lu, Huadong Lv, Xiaodan Luo, Xiuying Liu   +3 more
wiley   +1 more source

Harmonized global soil carbon and respiration datasets with derived turnover time and temperature sensitivity. [PDF]

Sci Data
Hashimoto S, Ito A, Nishina K.
europepmc   +1 more source

Down Syndrome due to de Novo Robertsonian Translocation Rob(21;21) in Mali

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Down syndrome (DS) is the most common chromosomal disorder among live births, most frequently resulting from free trisomy 21. Robertsonian translocations, which arise from the fusion of acrocentric chromosomes, represent a rare but clinically significant mechanism underlying DS.
Christine Ongoiba, Oumar Samassekou, Oumou Traoré, Cheick O. Sidibé, Modibo K. Goita, Guida Landouré, Mahamadou Traoré   +6 more
wiley   +1 more source

ENHYDROSS: A New Mechanistic Model Supports the Trans‐Oceanic Dispersal Capability of Terrestrial Vertebrates

Ecology and Evolution, Volume 16, Issue 4, April 2026.
We introduce ENHYDROSS, a new mechanistic model that uses optimal swimming speed and minimum cost of transport to estimate maximum dispersal distances and durations for vertebrates, enabling assessment of long‐distance oceanic dispersal potential. Applied to a range of extant and extinct animals, the model's estimates generally align with observed data;
Alexandros Pantelides, Paul Upchurch, Philip D. Mannion, Elias Gravanis, Donald M. Henderson, Phaedon Kyriakidis   +5 more
wiley   +1 more source

Consensus Molecules Associated with Parkinson's Disease. [PDF]

Neurol Int
Eyal S, Alfasi S, Ben Zaken K, Sawaid IO, Segev L, Mesfin S, Frankel P, Ezzy R, Saha-Detroja T, Madhavan S, Bloch N, Polis B, Samson AO.   +12 more
europepmc   +1 more source