Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
Benchmarking Q fever transmission in czech republic and serbia: A one health sub-national population study. [PDF]
Holý O +11 more
europepmc +1 more source
Iflaviruses in arthropods: when small is mighty
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
Surveillance of Q Fever in Dairy Cattle in Latvia: Molecular and Serological Findings and Association with Farm and Woodland Density. [PDF]
Boikmanis G +7 more
europepmc +1 more source
De Stupro: First Insights on Rape and Its Prosecution in Maltese Courts (1701–10)
Abstract This article constitutes a first in‐depth investigation of rape and the prosecution of this crime in early eighteenth‐century Malta. The research, which is based on sixteen rape accusations claimed at the secular courts in Malta between 1701 and 1710, has analysed cases categorized as ‘simple rape’, ‘violent rape’ and rape committed under the ...
Vanessa Buhagiar
wiley +1 more source
Retraction: A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever. [PDF]
PLOS One Editors.
europepmc +1 more source
Ligelizumab re‐treatment in CSU patients showed sustained efficacy and tolerability. Over 50% achieved symptom control (UAS7 ≤ 6) by Week 12; benefits maintained through Week 52. No new safety signals observed; aligns with prior PEARL trial outcomes. CSU, chronic spontaneous urticaria; mg, milligram; q4w, every 4 weeks; UAS, urticaria activity score ...
Ana M. Gimenez‐Arnau +22 more
wiley +1 more source
B-cell peptide epitopes as diagnostic targets for Q fever in sheep. [PDF]
Kozytska T +9 more
europepmc +1 more source
In this historical pre–post cohort study, the implementation of physiological cardiotocography (PCI) interpretation was associated with reduced neonatal morbidity, neonatal acidosis, and neonatal unit admission. Adjusted cesarean section rates did not increase, supporting PCI as a promising approach to intrapartum fetal surveillance.
Sophia Andres +8 more
wiley +1 more source
Seroprevalence of Q fever among humans and animals in East Africa: a systematic review and meta-analysis. [PDF]
Kallu SA +6 more
europepmc +1 more source

