Results 141 to 150 of about 385,754 (304)

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Tradeoffs between brain and digestive tissues across elevations in Typhlomys daloushanensis: evidence for sexual dimorphism

Wildlife Biology, EarlyView.
To cope with highly stochastic and/or heterogeneous environmental conditions, animals must balance energy resource allocation across physiological processes. The digestive tract and brain exhibit structural variations under strong developmental and selective pressures that vary across environmental gradients both between and within species.
Yimei Yan, Bangqing Chen, Jifa Cui, Chris Newman, Boyu Lei, Nan Wu, Jinwei Wu, Jin Zhao, Christina D. Buesching, Youbing Zhou   +9 more
wiley   +1 more source

Q Fever Wildlife Reservoir

Emerging Infectious Diseases, 2005
Miguel G. Madariaga
doaj   +1 more source

The General Disease Factor (“d”): First Empirical Evidence From China

Med Research, EarlyView.
Hongyi Sun, Qinghuan He, Ting Su, Xiaoli Yang, Zhiwei Zhou   +4 more
wiley   +1 more source

Exploring marking methods for the predatory hoverfly Sphaerophoria rueppellii (Diptera: Syrphidae)

Insect Science, EarlyView.
As important pollinators and predators of aphids, hoverflies play an important role in ecosystems. This study focuses on identifying the best marking technique for the model species Sphaerophoria rueppellii that can be used to track hoverfly feeding and oviposition sites, evaluating three methods: rubidium (RbCl), fluorescein, and fluorescent dusts ...
Michele Violi, Elena Costi, Elena Monari, Daniele Sommaggio, Lara Maistrello   +4 more
wiley   +1 more source

Q Fever in Thailand

Emerging Infectious Diseases, 2003
Yupin Suputtamongkol, Jean-Marc Rolain, Kitti Losuwanaruk, Kanigar Niwatayakul, Chuanpit Suthinont, Wirongrong Chierakul, Kriangsak Pimda, Didier Raoult   +7 more
doaj   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source

History of Plague Research Center of Pasteur Institute of Iran (1952-2016)

Journal of Research on History of Medicine, 2017
Following outbreaks of plague in the West of Iran, Pasteur Institute of Iran (PII) established a research center for emerging and reemerging infectious diseases in Akanlu, a village of Hamadan, in 1952, and controlled this deadly disease by the support ...
Ehsan Mostafavi, Marjan Keypour
doaj  

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source