Results 151 to 160 of about 107,750 (262)

Biomimetic MCC950‐loaded cerium‐layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin‐induced mice

open access: yesBritish Journal of Pharmacology, EarlyView.
The CLMBM nanoparticle (NP) system demonstrates strong and targeted anti‐ROS, antiapoptotic and anti‐inflammatory properties within the pancreas, thereby inhibiting the onset and progression of type 1 diabetes. Background and Purpose The destruction of β‐cells in type 1 diabetes is driven by signalling cascades that ultimately lead to cell apoptosis ...
Huiwen Pang   +9 more
wiley   +1 more source

Worldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study

open access: yesClinical &Experimental Allergy, EarlyView.
Global Asthma Network Phase I surveyed children, adolescents, and adults worldwide to assess the prevalence of asthma, rhinoconjunctivitis, and eczema. Human Development Index (HDI) and Gini inequality index (GinI) were important explanatory factors for prevalence variability of these conditions, with hotspots in areas with high HDI and high GinI ...
Luis García‐Marcos   +15 more
wiley   +1 more source

Transient Hyperparathyroidism and Severe Intrauterine Osteopenia Linked to Novel Homozygous TRPV6 Deletion

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Placental calcium (Ca2+) transport is essential for foetal bone mineralisation and development, as well as for Ca2+ homoeostasis. Rare mutations in transient receptor potential vanilloid (TRPV) 6 of the infant cause insufficient maternal‐foetal Ca2+ transport through the placenta.
Teodora Grigore   +6 more
wiley   +1 more source

Control of human Q fever by vaccination: the journey to Q-VAX and beyond. [PDF]

open access: yesInfect Immun
Heinzen RA   +5 more
europepmc   +1 more source

Monitoring wildlife health for diseases with visible signs by integrating camera traps with marked individuals

open access: yesConservation Biology, EarlyView.
Abstract Monitoring wildlife health is essential for conservation and management, wildlife and livestock welfare, and public health in a One Health framework. Yet, wildlife health monitoring often requires long‐term fieldwork and intensive sampling, which can be costly or logistically challenging, especially for remote, rare, or elusive populations. To
Jonathan Tichon   +8 more
wiley   +1 more source

Environmental risk factors of human Q fever in Spain. [PDF]

open access: yesOne Health
Cifo D   +7 more
europepmc   +1 more source

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

open access: yesCell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu   +8 more
wiley   +1 more source

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