Results 1 to 10 of about 98,054 (191)
INNOVATIONS in Pharmacy, 2020 The QALY is an impossible construct; it defies common sense. It fails completely once we consider the axioms of fundamental measurement. Utilities as ordinal scales cannot be used to create QALYS. The QALY should never have been introduced to support the
Paul Langley
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A QALY is [still] a QALY is [still] a QALY?
BMC Medical EthicsDespite clinical evidence of drug superiority, therapeutic modalities, like combination immunotherapy, are mostly considered cost-ineffective due to their high costs per life year(s) gained.
Hamideh Mahdiani +2 more
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Immune checkpoint inhibitors-based therapies for first-line treatment of advanced ovarian cancer with non-BRCAm/HRD-negative: a cost-effectiveness analysis [PDF]
Journal of Ovarian ResearchBackground Emerging evidence supports the clinical potential of immune checkpoint inhibitors (ICIs) with or without bevacizumab and poly-(adenosine diphosphate-ribose) polymerase (PARP) inhibitors for refractory advanced ovarian cancer (AOC) with BRCA ...
Youwen Zhu +3 more
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Epidemiological and pharmacoeconomic aspects of HIV infection in military
Журнал инфектологии, 2021 The goals of the research are to determine the latent morbidity and financial losses of the Russian Ministry of Defense due to the dismissal of service members with HIV infection at symptomatic stages; to establish the supposed clinical and ...
Yu. I. Bulankov +6 more
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Modelling the Health Economic Impact of Influenza Vaccination Strategies for High-Risk Children in Vietnam [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: In Vietnam, since 2011 a National Influenza Surveillance System in Vietnam has implemented Severe Acute Respiratory Infection (SARI) surveillance to assemble information and inform administrational and methods of prevention.
Trung Quang Vo +3 more
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Сибирский онкологический журнал, 2017 A new generation of aromatase inhibitors and target therapy directed at cycline-dependent kinases 4 and 6 gives a new opportunity to treat metastatic breast cancer. However, the cost of innovative therapy remains high.
S. L. Pavlinsky, P. I. Shabalkin
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Calculating QALYs, comparing QALY and DALY calculations [PDF]
Health Policy and Planning, 2006 Quality-adjusted life years (QALYs) have been used in the assessment of health interventions for three decades. The popularity of the QALY approach has been constantly increasing, although the debate on its theoretical underpinnings and practical implications is still ongoing.
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Controversies around QALYs [PDF]
Vnitřní lékařství, 2017 The paper summarizes the criticisms of the QALY concept utilization in health-economic evaluations that has been growing stronger in the last years. Despite of its limitations, the QALY concept has been routinely used in many countries incl. the Czech Republic.
Vladimír, Rogalewicz, Miroslav, Barták
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Вопросы современной педиатрии, 2014 Aim: To create the Russian-language version of the standardized international questionnaire Health Utilities Index (HUI) applicable for children's age, on the basis of the relevant international requirements to linguistic ratification and validation of ...
I. V. Vinyarskaya +4 more
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Health economic evaluation of gene replacement therapies: methodological issues and recommendations
Journal of Market Access & Health Policy, 2020 Objective: To provide recommendations for addressing previously identified key challenges in health economic evaluations of Gene Replacement Therapies (GRTs), including: 1) the assessment of clinical effectiveness; 2) the valuation of health outcomes; 3)
Samuel Aballéa +15 more
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