A QALY is [still] a QALY is [still] a QALY? [PDF]
Despite clinical evidence of drug superiority, therapeutic modalities, like combination immunotherapy, are mostly considered cost-ineffective due to their high costs per life year(s) gained.
Hamideh Mahdiani +2 more
doaj +3 more sources
Economic evaluations of pharmacogenetic and pharmacogenomic screening tests : a systematic review : second update of the literature [PDF]
Objective : Due to extended application of pharmacogenetic and pharmacogenomic screening (PGx) tests it is important to assess whether they provide good value for money. This review provides an update of the literature. Methods : A literature search was
Annemans, Lieven +7 more
core +38 more sources
Fair pricing, fair access; a systematic review of cost-effectiveness of new hyperlipidemia injectable medication in developing countries [PDF]
Introduction Lipid-lowering therapy is central to cardiovascular disease (CVD) management. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) inhibitors (alirocumab, evolocumab) and inclisiran offer greater low-density lipoprotein cholesterol (LDL-C ...
Samad Azari +8 more
doaj +2 more sources
Epidemiological and pharmacoeconomic aspects of HIV infection in military
The goals of the research are to determine the latent morbidity and financial losses of the Russian Ministry of Defense due to the dismissal of service members with HIV infection at symptomatic stages; to establish the supposed clinical and ...
Yu. I. Bulankov +6 more
doaj +1 more source
The relative value of different QALY types [PDF]
The oft-applied assumption in the use of Quality Adjusted Life Years (QALYs) in economic evaluation, that all QALYs are valued equally, has been questioned from the outset.
Bulfone, Liliana +6 more
core +2 more sources
Modelling the Health Economic Impact of Influenza Vaccination Strategies for High-Risk Children in Vietnam [PDF]
Introduction: In Vietnam, since 2011 a National Influenza Surveillance System in Vietnam has implemented Severe Acute Respiratory Infection (SARI) surveillance to assemble information and inform administrational and methods of prevention.
Trung Quang Vo +3 more
doaj +1 more source
The QALY is an impossible construct; it defies common sense. It fails completely once we consider the axioms of fundamental measurement. Utilities as ordinal scales cannot be used to create QALYS. The QALY should never have been introduced to support the
Paul Langley
doaj +1 more source
How to allocate scarce health resources without discriminating against people with disabilities [PDF]
One widely used method for allocating health care resources involves the use of cost-effectiveness analysis (CEA) to rank treatments in terms of quality-adjusted life-years (QALYs) gained.
John, Tyler M. +2 more
core +1 more source
A new generation of aromatase inhibitors and target therapy directed at cycline-dependent kinases 4 and 6 gives a new opportunity to treat metastatic breast cancer. However, the cost of innovative therapy remains high.
S. L. Pavlinsky, P. I. Shabalkin
doaj +1 more source
Opportunities for improving the efficiency of paediatric HIV treatment programmes [PDF]
Objectives: To conduct two economic analyses addressing whether to: routinely monitor HIV-infected children on antiretroviral therapy (ART) clinically or with laboratory tests; continue or stop cotrimoxazole prophylaxis when children become stabilized on
Bakeera-Kitaka, S +13 more
core +1 more source

