Results 11 to 20 of about 73,703 (332)
Calculating QALYs, comparing QALY and DALY calculations [PDF]
Quality-adjusted life years (QALYs) have been used in the assessment of health interventions for three decades. The popularity of the QALY approach has been constantly increasing, although the debate on its theoretical underpinnings and practical implications is still ongoing.
openaire +2 more sources
Aim: To create the Russian-language version of the standardized international questionnaire Health Utilities Index (HUI) applicable for children's age, on the basis of the relevant international requirements to linguistic ratification and validation of ...
I. V. Vinyarskaya +4 more
doaj +1 more source
National Institute for Clinical Excellence and its value judgments [PDF]
The National Institute for Clinical Excellence (NICE) offers health professionals in England and Wales advice on providing NHS patients with the highest attainable standards of care.
Culyer, A.J., Rawlins, M.D.
core +2 more sources
Controversies around QALYs [PDF]
The paper summarizes the criticisms of the QALY concept utilization in health-economic evaluations that has been growing stronger in the last years. Despite of its limitations, the QALY concept has been routinely used in many countries incl. the Czech Republic.
Vladimír, Rogalewicz, Miroslav, Barták
openaire +2 more sources
Health economic evaluation of gene replacement therapies: methodological issues and recommendations
Objective: To provide recommendations for addressing previously identified key challenges in health economic evaluations of Gene Replacement Therapies (GRTs), including: 1) the assessment of clinical effectiveness; 2) the valuation of health outcomes; 3)
Samuel Aballéa +15 more
doaj +1 more source
Health-related quality of life (HRQL) is a value correlating with life duration, which depends on person’s disturbances, current functional condition, self-perception and social abilities, which are influenced by diseases, traumas, treatment and private ...
A. A. Baranov +7 more
doaj +1 more source
Cost effectiveness of treatments for wet age-related macular degeneration [PDF]
Age-related macular degeneration (AMD) is a leading cause of blindness in people aged >= 50 years. Wet AMD in particular has a major impact on patient quality of life and imposes substantial burdens on healthcare systems.
Annemans, Lieven +4 more
core +1 more source
The effect of PD-L1 testing on the cost-effectiveness and economic impact of immune checkpoint inhibitors for the second-line treatment of NSCLC [PDF]
Background: Immune checkpoint inhibitors improve outcomes compared with chemotherapy in lung cancer. Tumor PD-L1 receptor expression is being studied as a predictive biomarker. The objective of this study was to assess the cost-effectiveness and economic
Abdel-Rahman +25 more
core +3 more sources
Laparoscopic versus open colorectal resection for cancer and polyps: A cost-effectiveness study [PDF]
Methods: Participants were recruited in 2006-2007 in a district general hospital in the south of England; those with a diagnosis of cancer or polyps were included in the analysis.
Dowson, H +4 more
core +1 more source
Age-Differentiated Qaly Losses [PDF]
In this paper we evaluate the QALY loss, which may be assigned to the prevalence of specific chronic illnesses and physical handicaps. The analysis is based on an individual self-rating health satisfaction question asked in the British Household Panel Survey data set.
van Praag, B.M.S. +1 more
openaire +4 more sources

