Results 21 to 30 of about 93,483 (103)

Fremy’s Salt-Mediated Oxidative Addition. A New Approach in the Total Synthesis of Naturally Dipetalolactone and Its Immunomodulatory Activity

open access: yesMolecules, 2013
The structure of the natural dipyranocoumarin dipetalolactone has been confirmed by an unambiguous synthetic route from resorcinol. This sequence was initiated by a pyran ring formation step which introduced the 3-chloro-3-methylbut-1-yne moiety.
Yasser Selim, Nabil Ouf, Mohamed Sakran
doaj   +1 more source

Synthesis of 2’-Modified Nucleotides

open access: yesMolecules, 2000
We show in this work the development of modified building blocks for the synthesis of nuclease resistant hammerhead ribozymes. These modified monomers retain the 2’-OH which is essential for the activity of these molecules.
Adolfo Iribarren   +2 more
doaj   +1 more source

GAMMA-RAY AND OPTICAL OSCILLATIONS IN PKS 0537–441 [PDF]

open access: yes, 2015
We have considered the Fermi γ-ray light curve of the blazar PKS 0537–441 during a high state extending from 2008 August 10 to 2011 August 27. The periodogram exhibits a peak at T ∼ 280 days, with a significance of ∼99.7%.
A. Sandrinelli, S. Covino, A. Treves
semanticscholar   +1 more source

Process Engineering Accelerating an Economic Industrialization Towards a Bio-Based World

open access: yesMolecules, 2019
The transition towards a bio-based world is a challenging undertaking. This perspective paper, from an engineering point of view, aims to provide an overview of existing projects and academic disciplines highlighting the potential benefit of increased ...
Lukas Uhlenbrock   +2 more
doaj   +1 more source

Aconitum pseudo-laeve var. erectum Inhibits Receptor Activator of Nuclear Factor Kappa-B Ligand-Induced Osteoclastogenesis via the c-Fos/nuclear Factor of Activated T-Cells, Cytoplasmic 1 Signaling Pathway and Prevents Lipopolysaccharide-Induced Bone Loss in Mice

open access: yesMolecules, 2014
Aconitum pseudo-laeve var. erectum (APE) has been widely shown in herbal medicine to have a therapeutic effect on inflammatory conditions. However, there has been no evidence on whether the extract of APE is involved in the biological bone metabolism ...
Jong Min Baek   +7 more
doaj   +1 more source

Hexagonal Mesoporous Silica as a Rapid, Efficient and Versatile Tool for MALDI-TOF MS Sample Preparation in Clinical Peptidomics Analysis: A Pilot Study

open access: yesMolecules, 2019
Improvement in high-throughput MALDI-TOF MS analysis requires practical and efficient sample preparation protocols for high acquisition rates. The use of hexagonal mesoporous silica (HMS) sorbents in combination with MALDI-TOF MS was explored as a ...
Rosa Terracciano   +4 more
doaj   +1 more source

Production of Micro- and Nanoscale Lignin from Wheat Straw Using Different Precipitation Setups

open access: yesMolecules, 2018
Micro- and nanosize lignin has recently gained interest due to its improved properties compared to standard lignin available today. As the second most abundant biopolymer after cellulose, lignin is readily available but used for rather low-value ...
Stefan Beisl   +4 more
doaj   +1 more source

Bioremediation of methylene blue dye using Bacillus subtilis MTCC 441.

open access: yesWater Science and Technology, 2017
Methylene blue (MB) commonly found in the textile industry effluent has been chosen as a model dye to investigate bioremediation using Bacillus subtilis MTCC 441. Both free cells and calcium alginate immobilized cells have been used to remove MB from the
Ganta Upendar   +3 more
semanticscholar   +1 more source

Selectivity of Terpyridine Platinum Anticancer Drugs for G-quadruplex DNA

open access: yesMolecules, 2019
Guanine-rich DNA can form four-stranded structures called G-quadruplexes (G4s) that can regulate many biological processes. Metal complexes have shown high affinity and selectivity toward the quadruplex structure.
Delphine Naud-Martin   +7 more
doaj   +1 more source

Reference Question Data Mining [PDF]

open access: yes, 2010
This exploratory study investigated the feasibility of using reference questions as an important tool in the construction of study guides, instructional outreach, and collection development at a small, four-year university in Lake Charles, Louisiana. The
Finnell, Joshua, Fontane, Walt
core   +1 more source

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