Results 1 to 10 of about 105,441 (51)

Integration of morpho-physico-biochemical traits with SSR and SRAP markers for characterization of castor genotypes of Indian origin

Oil Crop Science, 2022
Castor (Ricinus communis L.) is an important tropical oilseed crop, whose oil has versatile, practical value, especially in industries. The present study aimed to estimate the nature and magnitude of variability in the castor germplasm concerning yield ...
Akhila S. R, Sushil Kumar, Amar A. Sakure, Dipak A. Patel, Mukesh P. Patel   +4 more
doaj   +1 more source

Characterization of transposable elements within the Bemisia tabaci species complex

Mobile DNA, 2022
Background Whiteflies are agricultural pests that cause negative impacts globally to crop yields resulting at times in severe economic losses and food insecurity. The Bemisia tabaci whitefly species complex is the most damaging in terms of its broad crop
Juan Paolo A. Sicat, Paul Visendi, Steven O. Sewe, Sophie Bouvaine, Susan E. Seal   +4 more
doaj   +1 more source

Gene interaction analysis of psoriasis in Chinese Han population

Molecular Genetics & Genomic Medicine, 2022
Background/aims Psoriasis is a chronic immune‐mediated inflammatory skin disease characterized by excessive proliferation of keratinocytes. It has a strong genetic predisposition; gene‐gene interactions are important genetic models for common diseases ...
Qiongqiong Xu, Xiaodong Zheng, Yiwen Mao, Weiwei Chen, Shirui Chen, Hui Zhang, Qi Zhen, Bao Li, Liang Yong, Huiyao Ge, Yafen Yu, Ruixue Zhang, Lu Cao, Hui Cheng, Wenjun Wang, Liangdan Sun   +15 more
doaj   +1 more source

Identification of a novel heterozygous SOX9 variant in a Chinese family with congenital heart disease

Molecular Genetics & Genomic Medicine, 2022
Background Previous studies of individuals with hereditary or sporadic congenital heart disease (CHD) have provided strong evidence for a genetic basis for CHD.
Li Gong, Chunyan Wang, Haiyang Xie, Jun Gao, Tengyan Li, Shenggui Qi, Binbin Wang, Jing Wang   +7 more
doaj   +1 more source

Identification of Neoantigens and Construction of Immune Subtypes in Prostate Adenocarcinoma

Frontiers in Genetics, 2022
Background: Messenger ribonucleic acid (mRNA) vaccine has been considered as a potential therapeutic strategy and the next research hotspot, but their efficacy against prostate adenocarcinoma (PRAD) remains undefined.
Yukui Gao, Guixin Wang, Yanzhuo Chen, Mingpeng Zhang, Wenlong Gao, Zhiqun Shang, Yuanjie Niu   +6 more
doaj   +1 more source

A nonsense mutation in MME gene associates with autosomal recessive late‐onset Charcot–Marie–Tooth disease

Molecular Genetics & Genomic Medicine, 2022
Background The genetic cause for the majority of patients with late‐onset axonal form of neuropathies have remained unknown. In this study we aimed to identify the causal mutation in a family with multiple affected individuals manifesting a range of ...
Zeinab Jamiri, Rana Khosravi, Mohammad Mehdi Heidari, Ebrahim Kiani, Javad Gharechahi   +4 more
doaj   +1 more source

CircFOXM1 acts as a ceRNA to upregulate SMAD2 and promote the progression of nasopharyngeal carcinoma

Molecular Genetics & Genomic Medicine, 2022
Background In recent years, the development of high‐throughput sequencing technology has promoted the rapid development of circRNA‐related research. Studies have found that circRNA plays a key role in a variety of tumors, but few people study the role of
Shuai Pei, Chengxian Ma, Jie Chen, Xinyu Hu, Mingyu Du, Tian Xu, Mengna Zhan, Ke Xue, Yufeng Zhang, Li Yin, Xia He   +10 more
doaj   +1 more source

Novel and recurrent nuclear gene variations in a cohort of Chinese progressive external ophthalmoplegia patients with multiple mtDNA deletions

Molecular Genetics & Genomic Medicine, 2022
Objectives This study aimed to investigate the clinical and genetic spectrum in Chinese patients with multiple mtDNA deletions presenting with autosomal‐inherited mitochondrial progressive external ophthalmoplegia (PEO).
Yue Hou, Xutong Zhao, Zhiying Xie, Meng Yu, He Lv, Wei Zhang, Yun Yuan, Zhaoxia Wang   +7 more
doaj   +1 more source

Evaluation of novel compound variants of CEP290 in prenatally suspected case of Meckel syndrome through whole exome sequencing

Molecular Genetics & Genomic Medicine, 2022
Background Meckel syndrome (MKS) is a fatal disease characterized by multisystem fibrosis during the prenatal or perinatal period. It has an autosomal recessive genetic pattern and is characterized by meningo occipital encephalocele, polycystic kidney ...
Meilian Peng, Shuai Han, Juan Sun, Xiaodong He, Yaer Lv, Liwei Yang   +5 more
doaj   +1 more source

The histone variant H2A.Z in gene regulation

Epigenetics & Chromatin, 2019
The histone variant H2A.Z is involved in several processes such as transcriptional control, DNA repair, regulation of centromeric heterochromatin and, not surprisingly, is implicated in diseases such as cancer.
Benedetto Daniele Giaimo, Francesca Ferrante, Andreas Herchenröther, Sandra B. Hake, Tilman Borggrefe   +4 more
doaj   +1 more source