Results 11 to 20 of about 46,022 (51)

Treatment of Symptomatic Lumbar Disc Degeneration with the VariLift-L Interbody Fusion System: Retrospective Review of 470 Cases

The International Journal of Spine Surgery, 2016
Background Many first generation stand-alone fusion cages required endplate decortication and surgical impaction during the procedure resulting in segmental subsidence, implant migration and loss of lordosis postoperatively. The primary objective of this
W. Neely, Frank Fichtel, D. D. del Monaco, J. Block   +3 more
semanticscholar   +1 more source

Effects of AVX-470, an Oral, Locally Acting Anti-Tumour Necrosis Factor Antibody, on Tissue Biomarkers in Patients with Active Ulcerative Colitis.

Journal of Crohn's & Colitis, 2016
BACKGROUND AND AIMS AVX-470 is an orally administered, bovine-derived, anti-tumour necrosis factor (TNF) antibody with local activity in the gastrointestinal tract.
D. Hartman, D. Tracey, Brenda R Lemos, E. Erlich, R. Burton, D. Keane, Rutvij Patel, Skaison Kim, K. Bhol, M. Harris, B. Fox   +10 more
semanticscholar   +1 more source

Blue 470 nm light suppresses the growth of Salmonella enterica and methicillin‐resistant Staphylococcus aureus (MRSA) in vitro

Lasers in Surgery and Medicine, 2015
Emerging evidence suggests that blue light can photo‐inactivate some bacteria of clinical importance. Consequently, we tested the hypothesis that 470 nm light can suppress growth of two recalcitrant bacteria, MRSA and Salmonella.
V. Bumah, D. Masson-Meyers, C. Enwemeka
semanticscholar   +1 more source

Intraocular Pressure-Lowering Activity of NCX 470, a Novel Nitric Oxide-Donating Bimatoprost in Preclinical Models.

Investigative Ophthalmology and Visual Science, 2015
PURPOSE The prostaglandin F2alpha (PGF2α) analogue bimatoprost lowers intraocular pressure (IOP) by increasing uveoscleral outflow at doses shown to elicit redness of the eye.
F. Impagnatiello, C. Toris, M. Batugo, G. Prasanna, V. Borghi, E. Bastia, E. Ongini, A. Krauss   +7 more
semanticscholar   +1 more source

TNP-470 skews DC differentiation to Th1-stimulatory phenotypes and can serve as a novel adjuvant in a cancer vaccine.

Blood Advances, 2018
Fumagillin is an antiangiogenic and antineoplastic fungal natural product, and TNP-470 is one of its most potent analogs. Decades of studies revealed that TNP-470 has potent anticancer activities via destruction of neovasculature.
D. Ho, R. Wong
semanticscholar   +1 more source

Comparison of Carboplatin and Doxorubicin‐Based Chemotherapy Protocols in 470 Dogs after Amputation for Treatment of Appendicular Osteosarcoma

Journal of Veterinary Internal Medicine, 2014
Background Many chemotherapy protocols have been reported for treatment of canine appendicular osteosarcoma (OSA), but outcome comparisons in a single population are lacking.
L. Selmic, J. Burton, D. Thamm, S. Withrow, S. Lana   +4 more
semanticscholar   +1 more source

AVX-470: A Novel Oral Anti-TNF Antibody with Therapeutic Potential in Inflammatory Bowel Disease

Inflammatory Bowel Diseases, 2013
Background:Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract, which is currently treated with injected monoclonal antibodies specific for tumor necrosis factor (TNF).
K. Bhol, D. Tracey, Brenda R Lemos, G. Lyng, E. Erlich, D. Keane, M. S. Quesenberry, A. Holdorf, Lisa D. Schlehuber, Shawn Clark, B. Fox   +10 more
semanticscholar   +1 more source

Records of the Moon‐forming impact and the 470 Ma disruption of the L chondrite parent body in the asteroid belt from U‐Pb apatite ages of Novato (L6)

, 2014
Novato, a newly observed fall in the San Francisco Bay area, is a shocked and brecciated L6 ordinary chondrite containing dark and light lithologies. We have investigated the U‐Pb isotope systematics of coarse Cl‐apatite grains of metamorphic origin in ...
Q. Yin, Qin Zhou, Qiu-li Li, Xian‐Hua Li, Yu Liu, G. Tang, A. Krot, P. Jenniskens   +7 more
semanticscholar   +1 more source

Blue light (470 nm) effectively inhibits bacterial and fungal growth

Letters in Applied Microbiology, 2012
Blue light (470 nm) LED antimicrobial properties were studied alone against bacteria and with or without the food grade photosensitizer, erythrosine (ERY) against filamentous fungi.
A. J. D. Lucca, C. Carter-Wientjes, K. A. Williams, Deepak Bhatnagar   +3 more
semanticscholar   +1 more source

Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.

Circulation, 1999
BACKGROUND Neovascularization within the intima of human atherosclerotic lesions is well described, but its role in the progression of atherosclerosis is unknown.
K. Moulton, E. Heller, M. Konerding, E. Flynn, W. Palinski, J. Folkman   +5 more
semanticscholar   +1 more source