Results 11 to 20 of about 152,996 (99)

MiRNA-470-5p suppresses epithelial-mesenchymal transition of embryonic palatal shelf epithelial cells by targeting Fgfr1 during palatogenesis

open access: yesExperimental biology and medicine, 2023
MicroRNAs (miRNAs) have been identified as crucial modulators of gene expression and to play a role in palatogenesis. The aim of this study was to explore the potential role and regulatory mechanisms of miRNAs during palatogenesis.
Jie Zhou   +6 more
semanticscholar   +1 more source

A Randomized, Controlled Comparison of NCX 470 (0.021%, 0.042%, and 0.065%) and Latanoprost 0.005% in Patients With Open-angle Glaucoma or Ocular Hypertension: The Dolomites Study

open access: yesJournal of glaucoma, 2022
Précis: NCX 470 0.042% and 0.065% were statistically superior in intraocular pressure (IOP) lowering to latanoprost 0.005%, and NCX 470 0.021% was noninferior. All NCX 470 concentrations were safe and well tolerated.
T. Walters   +7 more
semanticscholar   +1 more source

Berberine Suppresses Mice Depression Behaviors and Promotes Hippocampal Neurons Growth Through Regulating the miR-34b-5p/miR-470-5p/BDNF Axis

open access: yesNeuropsychiatric Disease and Treatment, 2021
Background Berberine has been found to inhibit the progression of depression disorder, but its specific mechanism is still unclear. MicroRNA (miRNA) is considered to play an important role in the progression of depression.
Yuhua Zhan   +3 more
semanticscholar   +1 more source

Helicobacter pylori CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation

open access: yesCancers, 2021
Simple Summary Various microbial pathogens target the actin-binding protein cortactin to promote their own uptake, proliferation and spread, and exhibit proposed roles in human cancerogenesis. We aimed to study the molecular mechanisms of how the gastric
Nicole Tegtmeyer   +3 more
semanticscholar   +1 more source

Patient characteristics and predictors of mortality in 470 adults admitted to a district general hospital in England with Covid-19

open access: yesEpidemiology and Infection, 2020
Understanding risk factors for death from Covid-19 is key to providing good quality clinical care. We assessed the presenting characteristics of the ‘first wave’ of patients with Covid-19 at Royal Oldham Hospital, UK and undertook logistic regression ...
J. V. Thompson   +12 more
semanticscholar   +1 more source

PGK1 inhibitor CBR-470-1 protects neuronal cells from MPP+

open access: yesAging, 2020
The neurotoxin MPP+ (1-methyl-4-phenylpyridinium ion) disrupts mitochondrial function leading to oxidative stress and neuronal death. Here we examine whether activation of the Keap1-Nrf2 cascade can protect SH-SY5Y neuroblastoma cells from MPP+-induced ...
Jin-yu Zheng   +6 more
semanticscholar   +1 more source

Deep 230-470 MHz VLA observations of the mini-halo in the Perseus cluster [PDF]

open access: yes, 2017
We present a low-frequency view of the Perseus cluster with new observations from the Karl G. Jansky Very Large Array (JVLA) at 230–470 MHz. The data reveal a multitude of new structures associated with the mini-halo. The mini-halo seems to be influenced
M. Gendron-Marsolais   +8 more
semanticscholar   +1 more source

Genome-Wide Characterization of Alternative Splicing Events and Their Responses to Cold Stress in Tilapia

open access: yesFrontiers in Genetics, 2020
Alternative splicing (AS) is an important post-transcriptional regulatory mechanism for cells to generate transcript variability and proteome diversity.
Bi Jun Li   +5 more
doaj   +1 more source

Synaptonemal complex components promote centromere pairing in pre-meiotic germ cells. [PDF]

open access: yesPLoS Genetics, 2013
Mitosis and meiosis are two distinct cell division programs. During mitosis, sister chromatids separate, whereas during the first meiotic division, homologous chromosomes pair and then segregate from each other.
Nicolas Christophorou   +2 more
doaj   +1 more source

MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO. [PDF]

open access: yesPLoS Genetics, 2016
A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages.
Nicole Kohrs   +15 more
doaj   +1 more source

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