Results 31 to 40 of about 146,455 (101)
Background The epigenetic age can now be extrapolated from one of several epigenetic clocks, which are based on age-related changes in DNA methylation levels at specific multiple CpG sites.
Tamar Shahal+9 more
doaj +1 more source
The irradiated, allogeneic, cellular CSF-470 vaccine plus Bacillus Calmette–Guerin (BCG) and recombinant human granulocyte macrophage-colony stimulating factor (rhGM-CSF) is being tested against medium-dose IFN-α2b in stages IIB–III cutaneous melanoma ...
J. Mordoh+13 more
semanticscholar +1 more source
Background Ligation-mediated PCR protocols have diverse uses including the identification of integration sites of insertional mutagens, integrating vectors and naturally occurring mobile genetic elements.
Joanna C. Dawes+14 more
doaj +1 more source
Infantile cerebellar-retinal degeneration (ICRD) is an extremely rare, infantile-onset neuro-degenerative disease, characterized by autosomal recessive inherited, global developmental delay (GDD), progressive cerebellar and cortical atrophy, and retinal ...
Dong Jun Ha+10 more
doaj +1 more source
There is a growing interest in standardizing gene-disease associations for the purpose of facilitating the proper classification of variants in the context of Mendelian diseases.
Sateesh Maddirevula+34 more
doaj +1 more source
Spermatogenesis in testis is an important process for sexual reproduction, and worldwide about 10–15 percent of couples suffer from infertility. It is of importance to study spermatogenesis at single cell level in both of human and model organisms ...
Peipei Qian+3 more
doaj +1 more source
BACKGROUND AND AIMS AVX-470 is an orally administered, bovine-derived, anti-tumour necrosis factor (TNF) antibody with local activity in the gastrointestinal tract.
D. Hartman+10 more
semanticscholar +1 more source
Background: Androgen alopecia (AGA), the most common type of alopecia worldwide, has become an important medical and social issue. Accumulating evidence indicates that long noncoding RNAs (lncRNAs) play crucial roles in the progression of various human ...
Jiachao Xiong+6 more
doaj +1 more source
PURPOSE The prostaglandin F2alpha (PGF2α) analogue bimatoprost lowers intraocular pressure (IOP) by increasing uveoscleral outflow at doses shown to elicit redness of the eye.
F. Impagnatiello+7 more
semanticscholar +1 more source
Genomic Reporter Constructs to Monitor Pathway-Specific Repair of DNA Double-Strand Breaks
Repair of DNA Double-Strand Breaks (DSBs) can be error-free or highly mutagenic, depending on which of multiple mechanistically distinct pathways repairs the break.
Bert van de Kooij, Haico van Attikum
doaj +1 more source