Results 41 to 50 of about 146,455 (101)

TNP-470 skews DC differentiation to Th1-stimulatory phenotypes and can serve as a novel adjuvant in a cancer vaccine.

open access: yesBlood Advances, 2018
Fumagillin is an antiangiogenic and antineoplastic fungal natural product, and TNP-470 is one of its most potent analogs. Decades of studies revealed that TNP-470 has potent anticancer activities via destruction of neovasculature.
D. Ho, R. Wong
semanticscholar   +1 more source

Sea Urchin as a Universal Model for Studies of Gene Networks

open access: yesFrontiers in Genetics, 2021
The purple sea urchin Strongylocentrotus purpuratus has been used for over 150 years as a model organism in developmental biology. Using this model species, scientists have been able to describe, in detail, the mechanisms of cell cycle control and cell ...
Leonid Adonin   +6 more
doaj   +1 more source

Global Survey, Expressions and Association Analysis of CBLL Genes in Peanut

open access: yesFrontiers in Genetics, 2022
Cystathionine γ-synthase (CGS), methionine γ-lyase (MGL), cystathionine β-lyase (CBL) and cystathionine γ-lyase (CGL) share the Cys_Met_Meta_PP domain and play important roles in plant stress response and development.
Weifang Ren   +15 more
doaj   +1 more source

Comparison of Carboplatin and Doxorubicin‐Based Chemotherapy Protocols in 470 Dogs after Amputation for Treatment of Appendicular Osteosarcoma

open access: yesJournal of Veterinary Internal Medicine, 2014
Background Many chemotherapy protocols have been reported for treatment of canine appendicular osteosarcoma (OSA), but outcome comparisons in a single population are lacking.
L. Selmic   +4 more
semanticscholar   +1 more source

Pharmacodynamic Gene Testing in Prader-Willi Syndrome

open access: yesFrontiers in Genetics, 2020
Prader-Willi syndrome (PWS) is a rare genetic disorder with a complex neurobehavioral phenotype associated with considerable psychiatric co-morbidity.
Janice Forster   +2 more
doaj   +1 more source

Feature Compression Applications of Genetic Algorithm

open access: yesFrontiers in Genetics, 2022
With the rapid development of molecular breeding technology and many new varieties breeding, a method is urgently needed to identify different varieties accurately and quickly.
Meiling Zou   +10 more
doaj   +1 more source

Genetic architecture of sex determination in fish: Applications to sex ratio control in aquaculture

open access: yesFrontiers in Genetics, 2014
Controlling the sex ratio is essential in finfish farming. A balanced sex ratio is usually good for broodstock management, since it enables to develop appropriate breeding schemes.
Paulino eMartínez   +5 more
doaj   +1 more source

Identification and characterization of satellite DNAs in Poa L.

open access: yesMolecular Cytogenetics, 2020
Background Poa L. is a large genus of grass in Gramineae, among which P. pratensis is widely cultivated as turf and forage. Satellite DNA is the main components of the plant genome.
Linna Wei   +6 more
doaj   +1 more source

Sex-Biased Population Admixture Mediated Subsistence Strategy Transition of Heishuiguo People in Han Dynasty Hexi Corridor

open access: yesFrontiers in Genetics, 2022
The Hexi Corridor was an important arena for culture exchange and human migration between ancient China and Central and Western Asia. During the Han Dynasty (202 BCE–220 CE), subsistence strategy along the corridor shifted from pastoralism to a mixed ...
Jianxue Xiong   +19 more
doaj   +1 more source

SVInterpreter: A Comprehensive Topologically Associated Domain-Based Clinical Outcome Prediction Tool for Balanced and Unbalanced Structural Variants

open access: yesFrontiers in Genetics, 2021
With the advent of genomic sequencing, a number of balanced and unbalanced structural variants (SVs) can be detected per individual. Mainly due to incompleteness and the scattered nature of the available annotation data of the human genome, manual ...
Joana Fino   +5 more
doaj   +1 more source

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