Results 11 to 20 of about 4,586 (212)

Functional verification of computationally predicted qnr genes [PDF]

Annals of Clinical Microbiology and Antimicrobials, 2013
BackgroundThe quinolone resistance (qnr) genes are widely distributed among bacteria. We recently developed and applied probabilistic models to identify tentative novel qnr genes in large public collections of DNA sequence data including fragmented ...
DG Larsson, Larsson, D. G. Joakim, Erik Kristiansson, Boulund, Fredrik, Fredrik Boulund, Kristiansson, Erik, Carl-Fredrik Flach, Flach, Carl-Fredrik, DG Joakim Larsson   +8 more
core   +4 more sources

A novel method to discover fluoroquinolone antibiotic resistance (qnr) genes in fragmented nucleotide sequences [PDF]

BMC Genomics, 2012
Background Broad-spectrum fluoroquinolone antibiotics are central in modern health care and are used to treat and prevent a wide range of bacterial infections.
Boulund Fredrik, Johnning Anna, Pereira Mariana Buongermino, Larsson DG Joakim, Kristiansson Erik   +4 more
doaj   +2 more sources

Association of qnr Genes and OqxAB Efflux Pump in Fluoroquinolone-Resistant Klebsiella pneumoniae Strains

International Journal of Microbiology, 2023
Background. The aim of this study was to investigate the frequency and relationship between plasmid-mediated quinolone resistance genes and OqxAB pump genes, as well as the genetic linkage in K.
Fereshteh Amereh, Mohammad Reza Arabestani, Seyed Mostafa Hosseini, Leili Shokoohizadeh   +3 more
doaj   +2 more sources

First Case of Qnr B6 and Qnr B7 Genes in Enterobacteriaceae Producing Extended-Spectrum Beta-Lactamases in Abidjan, Côte D'ivoire

South Asian Journal of Research in Microbiology, 2019
International audienceAims: The aim of this study was to characterize fluoroquinolone resistance genes in enterobacteriaceae that produce extended-spectrum β-lactamases, isolated in Abidjan. Place and Duration of Study: Pasteur Institute of Côte d'Ivoire
Anatole, Toty Abalé, Nathalie, Guessennd Kouadio, Fernique, Konan, Baguy, Ouattara Mohamed, Bertin, Tiékoura Konan, Victoire, Gadou, Joseph, Djaman Allico   +6 more
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Planejamento e vulnerabilidade na Nova QNR, Ceilândia [PDF]

, 2009
Monografia (graduação)—Universidade de Brasília, Instituto de Ciências Humanas, Departamento de Geografia, 2009.O Distrito Federal (DF) foi, desde o seu processo de criação, uma área de intensos fluxos migratórios causando uma rápida e desorganizada ...
Monteiro, Bruno da Costa
core   +4 more sources

Enhanced Bacterial Fitness Under Residual Fluoroquinolone Concentrations Is Associated With Increased Gene Expression in Wastewater-Derived qnr Plasmid-Harboring Strains

Frontiers in Microbiology, 2018
Plasmids harboring qnr genes confer resistance to low fluoroquinolone concentrations. These genes are of significant clinical, evolutionary and environmental importance, since they are widely distributed in a diverse array of natural and clinical ...
Ella Kaplan, Ella Kaplan, Roberto B. M. Marano, Roberto B. M. Marano, Edouard Jurkevitch, Eddie Cytryn   +5 more
doaj   +2 more sources

Determination of Pentapeptide Repeat Units in Qnr Proteins by the Structure-Based Alignment Approach [PDF]

Antimicrobial Agents and Chemotherapy, 2011
The Qnr proteins belong to the pentapeptide repeat protein family. Despite each pentapeptide repeat unit being an important structural determinant, accurately determining pentapeptide repeat units in the Qnr proteins through sequence-based alignments has
Jung Hun Lee, Kwang Seung Park, Jae Jin Lee, Choong-Min Kang, Da Un Jeong, Xing Wu, Byeong Chul Jeong, Sang Hee Lee   +7 more
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Increased expression of Qnr is sufficient to confer clinical resistance to ciprofloxacin in Escherichia coli [PDF]

Journal of Antimicrobial Chemotherapy, 2017
Background: Ciprofloxacin, a fluoroquinolone, targets two essential bacterial enzymes, DNA gyrase and topoisomerase IV. Plasmid-borne qnr genes, encoding proteins that protect DNA gyrase and topoisomerase IV from inhibition by fluoroquinolones ...
Garoff, Linnéa,, Kavita Yadav, Diarmaid Hughes, Hughes, Diarmaid, Yadav, Kavita,, Garoff, Linnéa, Yadav, Kavita, Hughes, Diarmaid,, Linnéa Garoff   +8 more
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A qnr-plasmid allows aminoglycosides to induce SOS in Escherichia coli [PDF]

eLife, 2022
The plasmid-mediated quinolone resistance (PMQR) genes have been shown to promote high-level bacterial resistance to fluoroquinolone antibiotics, potentially leading to clinical treatment failures.
Anamaria Babosan, David Skurnik, Anaëlle Muggeo, Gerald B Pier, Zeynep Baharoglu, Thomas Jové, Marie-Cécile Ploy, Sophie Griveau, Fethi Bedioui, Sébastien Vergnolle, Sophie Moussalih, Christophe de Champs, Didier Mazel, Thomas Guillard   +13 more
doaj   +6 more sources

The Emergence of Qnr-resistance Among Klebsiella pneumoniae spp in Zahedan: Qnr-resistance Among Klebsiella pneumoniae spp

Iranian Journal of Pharmaceutical Sciences, 2018
Although quinolone resistance results mostly from chromosomal mutations in Klebsiella pneumoniae, it may also be mediated by plasmid – encoded qnr determinants.
Shalibeik, Saman, Shahraki, Shahram, Mohammadzadeh Rostami, Farzaneh   +2 more
core   +2 more sources