Results 1 to 10 of about 237,818 (116)

Mcr colistin resistance gene: a systematic review of current diagnostics and detection methods. [PDF]

Microbiologyopen, 2019
The importance of colistin as a last‐resort antibiotic in treating carbapenem‐resistant infections as well as the increasing spread of colistin resistance in bacteria isolated from humans, animals, and the environment makes the need for better, simpler, and efficient diagnostics dire.
Osei Sekyere J.
europepmc   +2 more sources

BasS/BasR Two-Component System Affects the Sensitivity of Escherichia coli to Plantaricin BM-1 by Regulating the Tricarboxylic Acid Cycle

Frontiers in Microbiology, 2022
Plantaricin BM-1, a class IIa bacteriocin produced by Lactiplantibacillus plantarum BM-1, exhibits significant antibacterial activity against many gram-positive and gram-negative bacteria.
Yifei Liu, Yawen Wang, Xinyue Chen, Junhua Jin, Hui Liu, Yanling Hao, Hongxing Zhang, Yuanhong Xie   +7 more
doaj   +1 more source

Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of δ-cadinol

Microbial Cell Factories, 2022
Background Terpene synthases are versatile catalysts in all domains of life, catalyzing the formation of an enormous variety of different terpenoid secondary metabolites.
Marion Ringel, Nicole Dimos, Stephanie Himpich, Martina Haack, Claudia Huber, Wolfgang Eisenreich, Gerhard Schenk, Bernhard Loll, Thomas Brück   +8 more
doaj   +1 more source

Efficient D-allulose synthesis under acidic conditions by auto-inducing expression of the tandem D-allulose 3-epimerase genes in Bacillus subtilis

Microbial Cell Factories, 2022
Background D-allulose, a hexulose monosaccharide with low calorie content and high sweetness, is commonly used as a functional sugar in food and nutrition.
Mengkai Hu, Yuxia Wei, Rongzhen Zhang, Minglong Shao, Taowei Yang, Meijuan Xu, Xian Zhang, Zhiming Rao   +7 more
doaj   +1 more source

Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines

Microbial Cell Factories, 2022
Background Glycoengineering, in the biotechnology workhorse bacterium, Escherichia coli, is a rapidly evolving field, particularly for the production of glycoconjugate vaccine candidates (bioconjugation).
Emily J. Kay, Marta Mauri, Sam J. Willcocks, Timothy A. Scott, Jon Cuccui, Brendan W. Wren   +5 more
doaj   +1 more source

Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine

Microbial Cell Factories, 2020
Background l-Alanyl-l-glutamine (AQ) is a functional dipeptide with high water solubility, good thermal stability and high bioavailability. It is widely used in clinical treatment, post-operative rehabilitation, sports health care and other fields. AQ is
Jiangming Zhu, Wei Yang, Bohua Wang, Qun Liu, Xiaotong Zhong, Quanxiu Gao, Jiezheng Liu, Jianzhong Huang, Baixue Lin, Yong Tao   +9 more
doaj   +1 more source

Insects in confined swine operations carry a large antibiotic resistant and potentially virulent enterococcal community

BMC Microbiology, 2011
Background Extensive use of antibiotics as growth promoters in the livestock industry constitutes strong selection pressure for evolution and selection of antibiotic resistant bacterial strains.
Schal Coby, Ghosh Anuradha, Ahmad Aqeel, Zurek Ludek   +3 more
doaj   +1 more source

Lactate production yield from engineered yeasts is dependent from the host background, the lactate dehydrogenase source and the lactate export

Microbial Cell Factories, 2006
Background Metabolic pathway manipulation for improving the properties and the productivity of microorganisms is becoming a well established concept. For the production of important metabolites, but also for a better understanding of the fundamentals of ...
Valli Minoska, Zampella Giuseppe, De Gioia Luca, Sauer Michael, Branduardi Paola, Mattanovich Diethard, Porro Danilo   +6 more
doaj   +1 more source

Enhanced ethanol formation by Clostridium thermocellum via pyruvate decarboxylase

Microbial Cell Factories, 2017
Background Pyruvate decarboxylase (PDC) is a well-known pathway for ethanol production, but has not been demonstrated for high titer ethanol production at temperatures above 50 °C. Result Here we examined the thermostability of eight PDCs.
Liang Tian, Skyler J. Perot, Shuen Hon, Jilai Zhou, Xiaoyu Liang, Jason T. Bouvier, Adam M. Guss, Daniel G. Olson, Lee R. Lynd   +8 more
doaj   +1 more source

A Recombinant HAV Expressing a Neutralization Epitope of HEV Induces Immune Response against HAV and HEV in Mice

Viruses, 2017
Hepatitis A virus (HAV) and hepatitis E virus (HEV) are causative agents of acute viral hepatitis transmitted via the fecal–oral route. Both viruses place a heavy burden on the public health and economy of developing countries.
Kui Xiang, Yuri Kusov, Guan Ying, Wang Yan, Yi Shan, Wu Jinyuan, Yin Na, Zhou Yan, Li Hongjun, Sun Maosheng   +9 more
doaj   +1 more source