Results 11 to 20 of about 209,429 (67)

Evaluation of Beauvericin’s activity and mode of action against all life stages of L. tropica for cutaneous Leishmaniasis therapy

Frontiers in Cellular and Infection Microbiology
BackgroundLeishmaniasis, particularly its cutaneous form caused by Leishmania tropica, remains a significant global health concern due to the limitations of current treatments, including drug resistance, toxicity, and inconsistent efficacy.
Lynn Al Samra, Mohamad El Nahas, Ilham Mneimneh, Aia Sinno, Sima Tokajian, Kelven Rahy, Sergio Thoumi, Lazo Ali, Wael Yammine, Charbel Al Khoury   +9 more
doaj   +1 more source

Prevalence of antibiotic resistance genes its association with microbiota in raw milk of northwest Xinjiang

Frontiers in Microbiology
The issue of antibiotic resistance caused by antibiotic resistance genes (ARGs) has become a significant concern in environmental research in recent years, while raw milk is an important link in the food chain and has become one of the carriers and ...
Yan Zhao, Yan Zhao, Yifan Niu, Yifan Niu, Min Zhao, Wanting Huang, Yanan Qin, Yanan Qin   +7 more
doaj   +1 more source

High plant diversity alleviates the negative effects of nitrogen deposition on soil nitrogen cycling multifunctionality

Frontiers in Microbiology
IntroductionChanges in plant diversity and increased atmospheric nitrogen deposition independently influence soil nitrogen cycling in terrestrial ecosystems.
Zhuo Li, Zhuo Li, Xiaowei Liu, Minghui Zhang, Bin Zhang, Tao Zhang, Cameron Wagg, Cameron Wagg, Fu Xing   +8 more
doaj   +1 more source

Halophilic rhizobacteria promote growth, physiology and salinity tolerance in Sesamum indicum L. grown under salt stress

Frontiers in Microbiology
IntroductionSalt stress is a major global issue that negatively affects plant growth and physiological processes. Plant growth-promoting rhizobacteria (PGPR) are known to alleviate salt stress and promote plant growth.
Dharman Sridhar, Saleh S. Alheswairini, Jayanthi Barasarathi, Hesham Ali El Enshasy, Hesham Ali El Enshasy, Sundaram Lalitha, Sajad Hussain Mir, S. Nithyapriya, Riyaz Sayyed   +8 more
doaj   +1 more source

Metabolomic Alterations in Patients with Obesity and the Impact of Metabolic Bariatric Surgery: Insights for Future Research

Metabolites
Metabolomics has emerged as a vital tool for understanding the body’s responses to therapeutic interventions. Metabolic bariatric surgery (MBS) is widely recognized as the most effective treatment modality for severe obesity and its associated ...
Ioanna A. Anastasiou, Dimitris Kounatidis, Miikka-Juhani Honka, Natalia G. Vallianou, Eleni Rebelos, Nikolaos Nektarios Karamanolis, Maria Dalamaga, Constantinos Pantos, Iordanis Mourouzis   +8 more
doaj   +1 more source

DHFR Inhibitors Display a Pleiotropic Anti-viral Activity Against SARS-CoV-2: Insights Into the Mechanisms of Action [PDF]

Viruses, 2023
Iaconis D, Caccuri F, Manelfi C, Talarico C, Bugatti A, Filippini F, Zani A, Novelli R, Kuzikov M, Ellinger B, Gribbon P, Riecken K, Esposito F, Corona A, Tramontano E, Beccari AR, Caruso A, Allegretti M.   +17 more
europepmc   +2 more sources

Nutri-Epigenetic Regulation of Vitamin D—Impact on Metabolism and Biological Functions: Narrative Review

Metabolites
Vitamin D deficiency is widespread. It increases the risk of several diseases. Therefore, researchers have long studied the factors that influence vitamin D levels in the body.
Magdalena Kowalówka, Ilona Górna, Marta Karaźniewicz-Łada, Dominika Kusyk, Juliusz Przysławski, Sławomira Drzymała-Czyż   +5 more
doaj   +1 more source

Imprint Desorption Electrospray Ionization Mass Spectrometry Imaging (IDESI-MSI) Reveals Absorption of Triclopyr-Based Herbicide in Plants and Mouse Organs

Metabolites
Background: Understanding the absorption and distribution of herbicides in plants and animal tissues is essential for assessing their potential risks to human health.
Hanzhi Liu, Yunshuo Tian, Ruolun Wei, Yifan Meng, Richard N. Zare   +4 more
doaj   +1 more source

Assessment of Metabolic Alterations Induced by Halogenated Additives and Antifungal Activity of Extracts from the Endophytic Fungus Fusarium sp. Associated with Dizygostemon riparius (Plantaginaceae)

Metabolites
Background/Objectives: Endophytic fungi are valuable sources of bioactive compounds with potential therapeutic applications. This study aimed to evaluate the antifungal activity of secondary metabolites produced by Fusarium sp. isolated from Dizygostemon
Hilzimar de Jesus Freitas Sá, Anne Karoline Maiorana Santos, Adriano Souza Fonseca, Lourivaldo da Silva Santos, Josivan Regis Farias, Rosane Nassar Meireles Guerra, Edson Rodrigues-Filho, Gilmar Silverio da Silva, Cleydlenne Costa Vasconcelos, Alberto Jorge Oliveira Lopes, Antônio José Cantanhede Filho   +10 more
doaj   +1 more source

In Vitro Metabolism of Doping Agents (Stanozolol, LGD-4033, Anastrozole, GW1516, Trimetazidine) by Human Seminal Vesicle and Liver Fractions

Metabolites
Background: In order to address complex scenarios in anti-doping science, especially in cases where an unintentional exposure of athletes to prohibited substances and a corresponding contamination of doping control samples at the collection event are ...
Johanna Sternberg, Insa Peters, Nana Naumann, Andreas Thomas, Mario Thevis   +4 more
doaj   +1 more source