Results 11 to 20 of about 216,418 (115)

Simultaneous Millimeter-wave, Gamma-Ray, and Optical Monitoring of the Blazar PKS 2326-502 during a Flaring State [PDF]

Astrophysical Journal Letters, 2023
Including millimeter-wave data in multiwavelength studies of the variability of active galactic nuclei (AGN) can provide insights into AGN physics that are not easily accessible at other wavelengths.
J. C. Hood II, A. Simpson, A. McDaniel, A. Foster, P. Ade, M. Ajello, A. J. Anderson, J. Austermann, J. Beall, A. Bender, B. Benson, F. Bianchini, L. Bleem, J. Carlstrom, C. Chang, P. Chaubal, H. Chiang, T. Chou, R. Citron, C. C. Moran, T. Crawford, A. Crites, T. de Haan, M. Dobbs, W. Everett, J. Gallicchio, E. George, N. Gupta, N. Halverson, G. Hilton, G. Holder, W. Holzapfel, J. Hrubeš, N. Huang, J. Hubmayr, K. Irwin, L. Knox, A. Lee, D. Li, A. Lowitz, G. Madejski, M. Malkan, J. McMahon, S. Meyer, J. Montgomery, T. Natoli, J. Nibarger, G. Noble, V. Novosad, Y. Omori, S. Padin, S. Patil, C. Pryke, C. Reichardt, J. Ruhl, B. Saliwanchik, K. Schaffer, C. Sievers, G. Smecher, A. Stark, C. Tucker, T. Veach, J. Vieira, G. Wang, N. Whitehorn, W. L. K. Wu, V. Yefremenko, J. Zebrowski, L. Zhang   +68 more
semanticscholar   +1 more source

Role of MicroRNA-502-3p in Human Diseases

Pharmaceuticals, 2023
MicroRNAs (miRNAs) are non-coding RNAs that play a major role in gene regulation in several diseases. MicroRNA-502-3p (MiR-502-3p) has been previously characterized in a variety of human diseases such as osteoporosis, diabetes, tuberculosis, cancers, and
Davin Devara, Yashmit Choudhary, Subodh Kumar   +2 more
semanticscholar   +1 more source

Concordance between microsatellite instability and mismatch repair protein expression in colorectal cancer and their clinicopathological characteristics: a retrospective analysis of 502 cases

Frontiers in Oncology, 2023
Microsatellite instability (MSI) is one of the hallmarks of colorectal cancer (CRC). Mismatch repair (MMR) protein expression may reflect MSI status.
M. Ye, G. Ru, Hang Yuan, Lili Qian, Xianglei He, Shuangshuang Li   +5 more
semanticscholar   +1 more source

FOXO1-Induced miR-502-3p Suppresses Colorectal Cancer Cell Growth through Targeting CDK6

Journal of Oncology, 2023
Colorectal cancer (CRC) is the most common tumor of the digestive system and the third most common tumor worldwide. To date, the prognosis of CRC patients remains poor. It is urgent to identify new therapeutic targets for CRC.
Hongwei Fan, Shuqiao Zhao, R. Ai, X. Niu, Junxia Zhang, Lin Liu   +5 more
semanticscholar   +1 more source

Exploring Cluster-Dependent Antibacterial Activities and Resistance Pathways of NOSO-502 and Colistin against Enterobacter cloacae Complex Species

Antimicrobial Agents and Chemotherapy, 2022
The Enterobacter cloacae complex (ECC) is a group of diverse environmental and clinically relevant bacterial species associated with a variety of infections in humans.
Lucile Pantel, F. Guérin, Marine Serri, F. Gravey, Jessica Houard, Kelly Maurent, M. Attwood, A. Noel, A. Macgowan, Emilie Racine, V. Cattoir, Maxime Gualtieri   +11 more
semanticscholar   +1 more source

Effect of masupirdine (SUVN‐502) on cognition in patients with moderate Alzheimer's disease: A randomized, double‐blind, phase 2, proof‐of‐concept study

Alzheimer's & Dementia, 2022
This study explored the efficacy and safety of a serotonin‐6 receptor antagonist, masupirdine, as adjunct treatment in patients with moderate Alzheimer's disease (AD) concomitantly treated with donepezil and memantine.
R. Nirogi, J. Ieni, V. Goyal, J. Ravula, S. Jetta, A. Shinde, P. Jayarajan, V. Benade, Veera Raghava Chowdary Palacharla, D. Dogiparti, V. Jasti, A. Atri, J. Cummings   +12 more
semanticscholar   +1 more source

CircCD44 plays oncogenic roles in triple-negative breast cancer by modulating the miR-502–5p/KRAS and IGF2BP2/Myc axes

Molecular Cancer, 2021
Emerging studies have revealed the potent functions of circRNAs in breast cancer tumorigenesis. However, the biogenesis, biofunction and mechanism of circRNAs in triple-negative breast cancer (TNBC) are largely unknown. High-throughput RNA sequencing was
Jie Li, Xinya Gao, Zhanqiang Zhang, Yuanhui Lai, Xunxun Lin, B. Lin, Maoguang Ma, Xiaoli Liang, Xixi Li, Weiming Lv, Ying Lin, Nu Zhang   +11 more
semanticscholar   +1 more source

PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

European Journal of Histochemistry, 2021
Therapeutic strategies for epithelial ovarian cancers are evolving with the advent of immunotherapy, such as PD-L1 inhibitors, with encouraging results. However, little data are available on PDL-1 expression in ovarian cancers.
Caroline Eymerit-Morin, A. Ilenko, T. Gaillard, J. Varinot, E. Compérat, S. Bendifallah, E. Darai   +6 more
semanticscholar   +1 more source

Potential beneficial effects of masupirdine (SUVN‐502) on agitation/aggression and psychosis in patients with moderate Alzheimer's disease: Exploratory post hoc analyses

International Journal of Geriatric Psychiatry, 2022
The effects of masupirdine on the neuropsychiatric symptoms were explored.
R. Nirogi, P. Jayarajan, V. Benade, A. Shinde, V. Goyal, S. Jetta, J. Ravula, R. Abraham, Venkata Ramalingayya Grandhi, R. Subramanian, S. Pandey, R. Badange, Abdul Rasheed Mohammed, V. Jasti, C. Ballard, J. Cummings   +15 more
semanticscholar   +1 more source

LncRNA LINC00473 is involved in the progression of invasive pituitary adenoma by upregulating KMT5A via ceRNA-mediated miR-502-3p evasion

Cell Death and Disease, 2021
Long noncoding RNAs (lncRNAs) and their crosstalks with other RNAs have been revealed to be closely related to tumorigenesis and development, but their role in invasive pituitary adenoma (IPA) remains largely unclear.
Junjun Li, Yuan Qian, Chao Zhang, Wei Wang, Yisheng Qiao, Hao Song, Liyan Li, Jia-zhi Guo, Di Lu, Xingli Deng   +9 more
semanticscholar   +1 more source