Results 31 to 40 of about 228,793 (115)

Validation of the antibacterial effect of topically applied tranexamic acid using in vitro and in vivo models

Frontiers in Microbiology
BackgroundSeveral studies have shown that tranexamic acid (TXA), an antifibrinolytic, reduces postoperative infection rates. Recent in vitro research showed that TXA alone and in combination with vancomycin and gentamicin had a synergistic effect against
Antonio Benjumea, Marta Díaz-Navarro, Marta Díaz-Navarro, Ángela Sai Gago-Campos, Andrés Visedo, Andrés Visedo, Rama Hafian, Emilia Cercenado, Emilia Cercenado, Mar Sánchez-Somolinos, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Javier Vaquero, Javier Vaquero, Javier Vaquero, Francisco Chana, María Guembe, María Guembe   +19 more
doaj   +1 more source

Hsa_circ_0000231 knockdown inhibits the glycolysis and progression of colorectal cancer cells by regulating miR-502-5p/MYO6 axis

World Journal of Surgical Oncology, 2020
Background Colorectal cancer (CRC) poses a heavy threat to human health owing to its high incidence and mortality. Circular RNAs (circRNAs) were investigated to participate in the progression of CRC, whereas there was no revenant data on the CRC process ...
Yanhe Liu, Hui Li, Xiaoyi Ye, Anlong Ji, Xiangwei Fu, Hai-bo Wu, Xiangyong Zeng   +6 more
semanticscholar   +1 more source

Detection and identification of wheat and barley phytopathogens in the Russian Federation

Microbiology Independent Research Journal, 2020
Grain export is an important branch of the food business in the Russian Federation. The countries of Europe, Asia, Africa, and South America are importers of Russian grain.
Olga Y. Slovareva
doaj   +1 more source

Tetracyclic homoisoflavanoid (+)-brazilin: a natural product inhibits c-di-AMP-producing enzyme and Streptococcus mutans biofilms

Microbiology Spectrum
The tenacious biofilms formed by Streptococcus mutans are resistant to conventional antibiotics and current treatments. There is a growing need for novel therapeutics that selectively inhibit S.
Edwin M. Rojas, Hua Zhang, Sadanandan E. Velu, Hui Wu   +3 more
doaj   +1 more source

Circular RNA circ_001842 plays an oncogenic role in renal cell carcinoma by disrupting microRNA‐502‐5p‐mediated inhibition of SLC39A14

Journal of Cellular and Molecular Medicine, 2020
Renal cell carcinoma (RCC) is a common urologic malignancy, and up to 30% of RCC patients present with locally advanced or metastatic disease at the time of initial diagnosis.
Jiawei Zeng, Qian Feng, Yaodong Wang, G. Xie, Yuanmeng Li, Yu-wei Yang, J. Feng   +6 more
semanticscholar   +1 more source

Fatty acids of Helicobacter pylori lipoproteins CagT and Lpp20

Microbiology Spectrum
Bacterial lipoproteins are post-translationally modified by the addition of acyl chains that anchor the protein to bacterial membranes. This modification includes two ester-linked and one amide-linked acyl chain on lipoproteins from Gram-negative ...
Mark S. McClain, William E. Boeglin, Holly M. Scott Algood, Alan R. Brash   +3 more
doaj   +1 more source

CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

Molecular Cancer, 2019
Accumulating evidence shows that, the dysregulation of circular RNAs (circRNAs) is associated with the progression of multiple malignancies. But, the underlying mechanisms by which has_circ_0032627 (circDLST) contributed to gastric cancer (GC) remain ...
Jing Zhang, Lidan Hou, Rui Liang, Xiaoyu Chen, Rui Zhang, Wei Chen, Jinshui Zhu   +6 more
semanticscholar   +1 more source

miR-502-5p affects gastric cancer progression by targeting PD-L1

Cancer Cell International, 2020
Studies have shown that miR-502-5p functions as a tumor suppressor and is associated with tumor growth and metastasis. This study intends to uncover the potential mechanism of miR-502-5p functioning as a tumor suppressor in gastric cancer.
Wendao You, Xiaoyu Liu, Yang Yu, Chen Chen, Y. Xiong, Yiting Liu, Yibin Sun, Chenhuan Tan, Hanshuo Zhang, Yadong Wang, Rui Li   +10 more
semanticscholar   +1 more source

Whole-genome sequencing of clinical isolates from tuberculosis patients in India: real-world data indicates a high proportion of pre-XDR cases

Microbiology Spectrum
Treatment decisions for tuberculosis (TB) in the absence of full drug-susceptibility data can result in amplifying resistance and may compromise treatment outcomes.
Aparna Bhanushali, Sachin Atre, Preethi Nair, Geethanjali Anilkumar Thandaseery, Sanchi Shah, Sanjana Kuruwa, Amrutraj Zade, Chaitali Nikam, Mangala Gomare, Anirvan Chatterjee   +9 more
doaj   +1 more source

miR-502-5p inhibits the proliferation, migration and invasion of gastric cancer cells by targeting SP1

Oncology Letters, 2020
Gastric cancer (GC) is the third most common cause of cancer-associated mortality in China. Aberrant microRNA (miR) expression can occur through multiple biological processes and has been implicated in cancer development.
Xiaobo Peng, Meihong Wu, Wuxia Liu, Chengtao Guo, L. Zhan, Xianbao Zhan   +5 more
semanticscholar   +1 more source