Results 31 to 40 of about 203,066 (67)

The Genome of the Medicinal Macrofungus Sanghuang Provides Insights Into the Synthesis of Diverse Secondary Metabolites

Frontiers in Microbiology, 2020
The mushroom, Sanghuang is widely used in Asian countries. This medicinal fungus produces diverse bioactive compounds and possesses a potent ability to degrade the wood of the mulberry tree.
Ying Shao, Hongwei Guo, Jianping Zhang, Hui Liu, Kun Wang, Song Zuo, Pengfei Xu, Zhenrong Xia, Qiumei Zhou, Hanghang Zhang, Xiangqing Wang, Anhui Chen, Yulong Wang   +12 more
doaj   +1 more source

Fitness Impaired Drug Resistant HIV-1 Is Not Compromised in Cell-to-Cell Transmission or Establishment of and Reactivation from Latency

Viruses, 2014
Both the presence of latently infected cells and cell-to-cell viral transmission are means whereby HIV can partially evade the inhibitory activities of antiretroviral drugs.
Sophie M. Bastarache, Thibault Mesplède, Daniel A. Donahue, Richard D. Sloan, Mark A. Wainberg   +4 more
doaj   +1 more source

Sulfate reduction controlled by organic matter availability in deep sediment cores from the saline, alkaline Lake Van (Eastern Anatolia, Turkey)

Frontiers in Microbiology, 2013
As part of the International Continental Drilling Program (ICDP) deep lake drilling project PaleoVan, we investigated sulfate reduction (SR) in deep sediment cores of the saline, alkaline (salinity 21.4 ‰, alkalinity 155 m mEq-1, pH 9.81) Lake Van ...
Clemens eGlombitza, Mona eStockhecke, Carsten J. Schubert, Alexandra eVetter, Jens eKallmeyer   +4 more
doaj   +1 more source

DHFR Inhibitors Display a Pleiotropic Anti-viral Activity Against SARS-CoV-2: Insights Into the Mechanisms of Action [PDF]

Viruses, 2023
Iaconis D, Caccuri F, Manelfi C, Talarico C, Bugatti A, Filippini F, Zani A, Novelli R, Kuzikov M, Ellinger B, Gribbon P, Riecken K, Esposito F, Corona A, Tramontano E, Beccari AR, Caruso A, Allegretti M.   +17 more
europepmc   +2 more sources

Detection and quantification of Lyme spirochetes using sensitive and specific molecular beacon probes

BMC Microbiology, 2009
Background Lyme disease, caused by Borrelia burgdorferi, affects a large number of people in both the USA and Europe. The mouse is a natural host for this spirochete and is widely used as a model system to study Lyme pathogenesis mechanisms.
Parveen Nikhat, Marras Salvatore AE, Saidac Diana S   +2 more
doaj   +1 more source

Anti-HFRS Human IgG Produced in Transchromosomic Bovines Has Potent Hantavirus Neutralizing Activity and Is Protective in Animal Models

Frontiers in Microbiology, 2020
We explored an emerging technology to produce anti-Hantaan virus (HTNV) and anti-Puumala virus (PUUV) neutralizing antibodies for use as pre- or post-exposure prophylactics.
Casey C. Perley, Rebecca L. Brocato, Hua Wu, Christoph Bausch, Priya P. Karmali, Jerel B. Vega, Melanie V. Cohen, Brandon Somerville, Steven A. Kwilas, Lucia M. Principe, Joshua Shamblin, Padmanabh Chivukula, Eddie Sullivan, Jay W. Hooper   +13 more
doaj   +1 more source

Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages

BMC Microbiology, 2002
Background Exported proteases are commonly associated with virulence in bacterial pathogens, yet there is a paucity of information regarding their role in Mycobacterium tuberculosis.
Ehlers Mario RW, Beyers Albert D, Gey van Pittius Nico C, Dave Joel A, Brown Gordon D   +4 more
doaj   +1 more source

Antisense RNA based down-regulation of RNaseE in E.coli

Microbial Cell Factories, 2006
Background Messenger RNA decay is an important mechanism for controlling gene expression in all organisms. The rate of the mRNA degradation directly affects the steady state concentration of mRNAs and therefore influences the protein synthesis.
Neubauer Peter, Kemmer Christian
doaj   +1 more source

Constant Light Exposure Alters Gut Microbiota and Promotes the Progression of Steatohepatitis in High Fat Diet Rats

Frontiers in Microbiology, 2020
BackgroundNon-alcoholic fatty liver disease (NAFLD) poses a significant health concern worldwide. With the progression of urbanization, light pollution may be a previously unrecognized risk factor for NAFLD/NASH development.
Lin Wei, Fangzhi Yue, Lin Xing, Shanyu Wu, Ying Shi, Jinchen Li, Xingwei Xiang, Sin Man Lam, Guanghou Shui, Ryan Russell, Dongmei Zhang   +10 more
doaj   +1 more source

Bacillus subtilis Nucleoid-Associated Protein YlxR Is Involved in Bimodal Expression of the Fructoselysine Utilization Operon (frlBONMD-yurJ) Promoter

Frontiers in Microbiology, 2020
Bacteria must survive harsh environmental fluctuations at times and have evolved several strategies. “Collective” behaviors have been identified due to recent progress in single-cell analysis.
Mitsuo Ogura, Kazutoshi Shindo, Yu Kanesaki   +2 more
doaj   +1 more source