Results 51 to 60 of about 209,429 (67)

Discovery of Dietary Plant Flavonols as Novel Potent Inhibitors Targeting DYRK1A Kinase

Biomolecules
DYRK1A kinase is a critical regulator in cellular signaling pathways and a promising therapeutic target for neurodegenerative diseases, diabetes and cancers.
Jin Jin, Qihong Zhou, Bin Guo, Zongchao Jia   +3 more
doaj   +1 more source

Hepatic Lipoprotein Metabolism: Current and Future In Vitro Cell-Based Systems

Biomolecules
Changes in hepatic lipoprotein metabolism are responsible for the majority of metabolic dysfunction-associated disorders, including familial hypercholesterolemia (FH), metabolic syndrome (MetS), metabolic dysfunction-associated fatty liver disease (MAFLD)
Izabella Kiss, Nicole Neuwert, Raimund Oberle, Markus Hengstschläger, Selma Osmanagic-Myers, Herbert Stangl   +5 more
doaj   +1 more source

Heparin-Binding Hemagglutinin-Induced Trained Immunity in Macrophages: Implications for Antimycobacterial Defense

Biomolecules
Tuberculosis (TB) is a major global health threat, with the current Bacillus Calmette–Guérin (BCG) vaccine having limited efficacy against adult pulmonary disease.
Yongqiang Li, Xiuping Jia, Jinhua Tang, Huilian Qiao, Jiani Zhou, Yueyun Ma   +5 more
doaj   +1 more source

Quiescence Multiverse

Biomolecules
Cellular quiescence is operationally defined as a temporary and reversible cessation of proliferation. This state encompasses a wide range of physiological situations since most cells, from microbes to cells composing complex tissues, spend most of their
Damien Laporte, Isabelle Sagot
doaj   +1 more source

The Role of Myeloid Differentiation Factor 2 in Stroke: Mechanisms and Therapeutic Potential

Biomolecules
Stroke represents a significant public health burden, ranking as a leading cause of death and disability globally. The prevalence of stroke increases with age, with ischemic stroke accounting for nearly 87% of cases globally.
Deyuan Zhu, Jihu Zhao, Qian Chen, Qiong Liu, Yibin Fang   +4 more
doaj   +1 more source

Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice. [PDF]

Antioxid Redox Signal, 2015
Cho HY, Jedlicka AE, Gladwell W, Marzec J, McCaw ZR, Bienstock RJ, Kleeberger SR.   +6 more
europepmc   +1 more source

34^th European Congress of Pathology - Abstracts. [PDF]

Virchows Arch, 2022
europepmc   +1 more source

Xenotropic and Other Murine Leukemia Virus-Related Viruses in Humans

Advances in Virology, 2011
Arifa S. Khan, Myra McClure, Yoshinao Kubo, Paul Jolicoeur   +3 more
doaj   +1 more source

Correction: Dietary supplementation with Chinese herb ultrafine powder improves intestinal morphology and physical barrier function by altering jejunal microbiota in laying hens

Frontiers in Microbiology
Jue Gui, Jue Gui, Md Abul Kalam Azad, Wenchao Lin, Wenchao Lin, Chengwen Meng, Chengwen Meng, Xin Hu, Yadong Cui, Wei Lan, Jianhua He, Xiangfeng Kong, Xiangfeng Kong, Xiangfeng Kong   +13 more
doaj   +1 more source

A genetically explicit model of speciation by sensory drive within a continuous population in aquatic environments. [PDF]

BMC Evol Biol, 2007
Kawata M, Shoji A, Kawamura S, Seehausen O.   +3 more
europepmc   +1 more source