Results 41 to 50 of about 216,418 (115)

Modulation of host biology by Pseudomonas aeruginosa quorum sensing signal molecules: messengers or traitors

Frontiers in Microbiology, 2015
Bacterial cells sense their population density and respond accordingly by producing various signal molecules to the surrounding environments thereby trigger a plethora of gene expression. This regulatory pathway is termed quorum sensing (QS).
Yi-Chia eLiu, Kok-Gan eChan, Chien-Yi eChang, Chien-Yi eChang   +3 more
doaj   +1 more source

The role of glycerophospholipid metabolism in feline parvovirus infected CRFK cells

Frontiers in Microbiology
BackgroundFeline panleukopenia, caused by the highly lethal feline parvovirus (FPV), lacks effective prevention and treatment strategies. This study aimed to elucidate the key metabolic regulatory mechanisms during FPV infection.MethodsCRFK cells were ...
Zhen Sun, Zhen Sun, Zhen Sun, Zhen Sun, Hongwei Zhu, Hongwei Zhu, Hongwei Zhu, Hongwei Zhu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Jianlong Zhang, Jianlong Zhang, Jianlong Zhang, Jianlong Zhang, Linlin Jiang, Linlin Jiang, Linlin Jiang, Linlin Jiang, Xin Yu, Xin Yu, Xin Yu, Xin Yu, Jiayu Yu, Jiayu Yu, Jiayu Yu, Jiayu Yu, Xingxiao Zhang, Xingxiao Zhang, Xingxiao Zhang, Xingxiao Zhang   +31 more
doaj   +1 more source

Engineered bacteriophage lysins as novel anti-infectives

Frontiers in Microbiology, 2014
Bacteriophage lysins, the highly evolved special peptidoglycan hydrolases, have long been demonstrated to be an effective enzybiotics in various infectious models. The modular structure of lysins makes it possible to design bioengineered lysins that have
hang eyang, junping eyu, Hongping eWei
doaj   +1 more source

Prolonged infusion of β-lactam antibiotics decreases short-term mortality in critically ill patients: A meta-analysis and trial sequential analysis from randomized control trials

Journal of Global Antimicrobial Resistance
: Objectives: The aim of this study was to ascertain the clinical efficacy of prolonged infusion of β-lactam antibiotics in critically ill patients and to provide additional evidence.
Baofang Liang, Jianwei Su, Ya Wang, Linxin Chen, Yuanchun Mo, Baocheng Xie   +5 more
doaj   +1 more source

Hsa_circ_0000231 knockdown inhibits the glycolysis and progression of colorectal cancer cells by regulating miR-502-5p/MYO6 axis

World Journal of Surgical Oncology, 2020
Background Colorectal cancer (CRC) poses a heavy threat to human health owing to its high incidence and mortality. Circular RNAs (circRNAs) were investigated to participate in the progression of CRC, whereas there was no revenant data on the CRC process ...
Yanhe Liu, Hui Li, Xiaoyi Ye, Anlong Ji, Xiangwei Fu, Hai-bo Wu, Xiangyong Zeng   +6 more
semanticscholar   +1 more source

HoloMoA: a holography and deep learning tool for the identification of antimicrobial mechanisms of action and the detection of novel MoA

Frontiers in Microbiology
We propose an innovative technology to classify the Mechanism of Action (MoA) of antimicrobials and predict their novelty, called HoloMoA. Our rapid, robust, affordable and versatile tool is based on the combination of time-lapse Digital Inline ...
Zohreh Sedaghat, Benoît Courbon, Héloïse Botrel, Hélène Dugua, Pawel Tulinski, Laethitia Alibaud, Lucia Pagani, Derry Mercer, Cyril Guyard, Christophe Védrine, Sophie Dixneuf   +10 more
doaj   +1 more source

Circular RNA circ_001842 plays an oncogenic role in renal cell carcinoma by disrupting microRNA‐502‐5p‐mediated inhibition of SLC39A14

Journal of Cellular and Molecular Medicine, 2020
Renal cell carcinoma (RCC) is a common urologic malignancy, and up to 30% of RCC patients present with locally advanced or metastatic disease at the time of initial diagnosis.
Jiawei Zeng, Qian Feng, Yaodong Wang, G. Xie, Yuanmeng Li, Yu-wei Yang, J. Feng   +6 more
semanticscholar   +1 more source

Inhibitory Effects of Eurotium cristatum on Growth and Aflatoxin B1 Biosynthesis in Aspergillus flavus

Frontiers in Microbiology, 2020
Probiotic strain Eurotium cristatum was isolated from Chinese Fuzhuan brick-tea and tested for its in vitro activity against aflatoxigenic Aspergillus flavus. Results indicated that E. cristatum can inhibit the radial growth of A. flavus.
Qiannan Zhao, Qiannan Zhao, Yue Qiu, Yue Qiu, Xin Wang, Xin Wang, Yuanyuan Gu, Yuzhu Zhao, Yidi Wang, Tianli Yue, Tianli Yue, Tianli Yue, Tianli Yue, Yahong Yuan, Yahong Yuan   +14 more
doaj   +1 more source

CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling

Molecular Cancer, 2019
Accumulating evidence shows that, the dysregulation of circular RNAs (circRNAs) is associated with the progression of multiple malignancies. But, the underlying mechanisms by which has_circ_0032627 (circDLST) contributed to gastric cancer (GC) remain ...
Jing Zhang, Lidan Hou, Rui Liang, Xiaoyu Chen, Rui Zhang, Wei Chen, Jinshui Zhu   +6 more
semanticscholar   +1 more source

miR-502-5p affects gastric cancer progression by targeting PD-L1

Cancer Cell International, 2020
Studies have shown that miR-502-5p functions as a tumor suppressor and is associated with tumor growth and metastasis. This study intends to uncover the potential mechanism of miR-502-5p functioning as a tumor suppressor in gastric cancer.
Wendao You, Xiaoyu Liu, Yang Yu, Chen Chen, Y. Xiong, Yiting Liu, Yibin Sun, Chenhuan Tan, Hanshuo Zhang, Yadong Wang, Rui Li   +10 more
semanticscholar   +1 more source