Prolonged QT interval: A tricky diagnosis? [PDF]
Prolonged heart-rate adjusted QT intervals on the electrocardiogram (ECG) are associated with an increased risk far coronary heart disease and sudden death. However, the diagnosis of the prolonged QT interval is hampered by lack of standards.
Bemmel, J.H. (Jan) van +6 more
core +1 more source
The importance of the epinephrine provocation test for the hidden type-1 congenital long QT syndrome
Congenital long QT syndrome (LQTS) is a genetic channelopathy associated with a high incidence of sudden cardiac death in children and young adults. QT interval prolongation is typically the primary finding on the electrocardiography (ECG) recordings ...
Adem Atici +3 more
doaj +1 more source
Screening for QT Prolongation in the Emergency Department: Is There a Better “Rule of Thumb?” [PDF]
Introduction: Identification of QT prolongation in the emergency department (ED) is critical for appropriate monitoring, disposition, and treatment of patients at risk for torsades de pointes (TdP).
Friedman, Ari B. +2 more
core
Palbociclib has no clinically relevant effect on the QTc interval in patients with advanced breast cancer. [PDF]
The aim of this study was to assess the potential effects of palbociclib in combination with letrozole on QTc. PALOMA-2, a phase 3, randomized, double-blind, placebo-controlled trial, compared palbociclib plus letrozole with placebo plus letrozole in ...
Durairaj, Chandrasekar +12 more
core +2 more sources
Recently, the effects of QT interval prolongation have received more attention among clinicians, industry, and official regulatory agencies. Some have advocated the total elimination or discontinuing development of drugs which prolong the QT interval. In
Tetsunori Saikawa, MD +2 more
doaj +1 more source
QT prolongation in HIV-positive patients: Review articleKey points
Introduction: Antiretrovirals have immensely increased the average life expectancy of HIV-positive patients. However, the incidence of QT interval prolongation and other arrhythmias has also increased. Methods: Pubmed and Google Scholar were searched for
Jing Liu +5 more
doaj +1 more source
QT peak prolongation predicts cardiac death following stroke [PDF]
Cardiac death has been linked in many populations to prolongation of the QT interval (QTe). However, basic science research suggested that the best estimate of the time point when repolarisation begins is near the T-wave peak.
Douglas, Denise +7 more
core +1 more source
Диспластические синдромы и фенотипы в оценке изменений интервала QT при малых аномалиях сердца
To assess relation of dysplastic syndromes and phenotypes to pathological QT interval in patients with minor cardiac anomalies, 128 patients aged 18–35 years were examined.
А. В. Ягода +2 more
doaj +3 more sources
Parameters of ventricular repolarization in patients with autoimmune hepatitis
Objective: Autoimmune hepatitis (AIH) is a liver disorder that affects both children and adults. It is characterized by inflammatory liver histology, elevated transaminase level, circulating nonorgan-specific autoantibodies, and increased level of ...
Burak Açar +11 more
doaj +1 more source
The QT Intervals in Infancy and Time for Infantile ECG Screening for Long QT Syndrome [PDF]
Background: Electrocardiographic and molecular studies have clarified an association between sudden infant death syndrome (SIDS) and long QT syndrome (LQTS), and few data are available for the QT interval in infancy from birth to 1 year of age ...
Yoshinaga, Masao +13 more
core +2 more sources

