Results 121 to 130 of about 73,159 (323)

Effect of artemisinin-piperaquine treatment on the electrocardiogram of malaria patients

Revista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION: Concern regarding the cardiotoxicity of antimalarials has been renewed because of their potential to cause QT/QTc interval prolongation related to torsade de pointes (TdP).
Wanting Wu, Yuan Liang, Guangchao Wu, Yinghang Su, Hongying Zhang, Zhenyan Zhang, Changsheng Deng, Qi Wang, Bo Huang, Bo Tan, Chongjun Zhou, Jianping Song   +11 more
doaj   +1 more source

Andersen-Tawil syndrome: report of 3 novel mutations and high risk of symptomatic cardiac involvement. [PDF]

, 2014
IntroductionAndersen-Tawil syndrome (ATS) is a potassium channelopathy affecting cardiac and skeletal muscle. Periodic paralysis is a presenting symptom in some patients, whereas, in others, symptomatic arrhythmias or prolongation of QT in ...
Bieganowska, Katarzyna, Bienias, Piotr, Kaminska, Anna, Kostera-Pruszczyk, Anna, Lee, Hsien-Yang, Miszczak-Knecht, Maria, Ploski, Rafal, Potulska-Chromik, Anna, Pruszczyk, Piotr, Ptáček, Louis J, Quinn, Emily, Szczałuba, Krzysztof   +11 more
core   +2 more sources

Lorazepam-Induced Prolongation of the QT Interval in a Patient with Schizoaffective Disorder and Complete AV Block [PDF]

, 2004
Marc Ziegenbein, Stefan Kropp
openalex   +1 more source

Sudden Death Associated with QT Interval Prolongation and KCNQ1 Gene Mutation in a Family of English Springer Spaniels

Journal of Veterinary Internal Medicine, 2015
Background A 5‐year‐old, healthy English Springer Spaniel died suddenly 4 months after delivering a litter of 7 puppies. Within 4 months of the dam's death, 3 offspring also died suddenly.
Wendy A. Ware, Y. Reina-Doreste, Y. Reina-Doreste, Joshua A. Stern, Joshua A. Stern, Kathryn M. Meurs, Kathryn M. Meurs   +6 more
semanticscholar   +1 more source

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

The Effects of the Adenosine Receptor Antagonists on the Reverse of Cardiovascular Toxic Effects Induced by Citalopram In-Vivo Rat Model of Poisoning

Balkan Medical Journal, 2015
Background: Citalopram is a selective serotonin reuptake inhibitor that requires routine cardiac monitoring to prevent a toxic dose. Prolongation of the QT interval has been observed in acute citalopram poisoning.
Müjgan Büyükdeligöz, Nil Hocaoğlu, Kubilay Oransay, Yeşim Tunçok, Şule Kalkan   +4 more
doaj   +1 more source

Correlation Between the Severity of Liver Cirrhosis (Chil-Pugh Score) and QTc Interval Prolongation [PDF]

, 2012
Background:Liver cirrhosis causes changes in cardiovascular system. Electrographic (ECG) abnormality commonly found in cirrhosis patients is QT interval prolongation. It is part of cirrhotic cardiomyopathy.
Bayupurnama, P. (Putut), Indrarti, F. (Fahmi), Maduseno, S. (Sutanto), Nurdjanah, S. (Siti), Ratnasari, N. (Neneng), Saksana, R. A. (Rachmad), Triwikatmani, C. (Catharina)   +6 more
core  

Increased Short-Term Beat-To-Beat Variability of QT Interval in Patients with Acromegaly. [PDF]

, 2015
Cardiovascular diseases, including ventricular arrhythmias are responsible for increased mortality in patients with acromegaly. Acromegaly may cause repolarization abnormalities such as QT prolongation and impairment of repolarization reserve enhancing ...
Baczkó, István, Csajbók, Éva, Czekus, C., Forster, Tamás, Gavaller, H., Lengyel, Csaba Attila, Magony, Sándor, Nemes, Attila, Orosz, Andrea, Papp, Gyula, Valkusz, Zsuzsanna, Varró, András, Várkonyi, Tamás, Wittmann, Tibor   +13 more
core   +3 more sources

QT PRODACT: In Vivo QT Assay in Anesthetized Dog for Detecting the Potential for QT Interval Prolongation by Human Pharmaceuticals

Journal of Pharmacological Sciences, 2005
The purpose of this study was to assess the utility of the isoflurane-anesthetized dog model for detecting the potential for QT interval prolongation by human pharmaceuticals.
Hiroyuki Tashibu, Hiroyasu Miyazaki, Kumiko Aoki, Yasuki Akie, Keiji Yamamoto   +4 more
doaj   +1 more source

ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. [PDF]

, 2019
Background:Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous activation of β-arrestin (a signaling pathway associated with opioid-related AEs) and G ...
Beard, Timothy L, Bergese, Sergio D, Berkowitz, Richard D, Brzezinski, Marek, Cochrane, Kristina, Habib, Ashraf S, Hammer, Gregory B, Mace, Sharon E, Minkowitz, Harold S, Pan, Peter H, Wase, Linda   +10 more
core