Results 121 to 130 of about 55,959 (291)

Glycemia and Corrected QT Interval Prolongation in Young Type 1 Diabetic Patients [PDF]

, 2006
Bert Suys, Sara Heuten, Daniël De Wolf, Marc Verherstraeten, L. Op De Beeck, Dirk Matthys, Christiaan Vrints, Raoul Rooman   +7 more
openalex   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Drug-Induced QT Prolongation: Individual Susceptibility and Regulatory Issues Related to Safety Pharmacology 5. QT Interval: Gender and Other Affecting Factors in the Clinical Setting

, 2006
Tetsunori Saikawa
openalex   +2 more sources

Electrophysiological characterization of pre‐adolescents born with intrauterine growth restriction: insights from clinical and computational data

The Journal of Physiology, EarlyView.
Abstract figure legend Depolarization and repolarization duration analysis was conducted in preadolescent groups with IUGR and controls using a 12‐lead ECG. Principal component analysis was applied over the 12‐lead ECGs to generate spatially transformed leads better suited for robust ECG fiducial points detection.
Freddy L. Bueno‐Palomeque, Ernesto Zacur, Esther Pueyo, Fàtima Crispi, Pablo Laguna, Ana Mincholé   +5 more
wiley   +1 more source

Drug-Induced QT Prolongation: Individual Susceptibility and Regulatory Issues Related to Safety Pharmacology 3. Assessment of Drug-Induced QT Interval Prolongation in Non-Clinical Test

, 2006
Atsushi Sugiyama
openalex   +2 more sources

Measurement and Management of QT Interval Prolongation for General Physicians

Journal of general internal medicine, 2019
P. Indraratna, D. Tardo, Madeline Delves, R. Szirt, B. Ng   +4 more
semanticscholar   +1 more source

The apicobasal dispersion of ventricular repolarization in humans is associated with age and affects arrhythmia vulnerability

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated the age‐ and sex‐related differences in the apicobasal repolarization gradient (ABRG) and evaluated their possible role inventricular arrhythmia vulnerability. Electrocardiographic imaging (ECGI) was performed in healthy subjects during sinus rhythm, and the average recovery time (RT) and activation–recovery ...
Vladimír Sobota, Job Stoks, Kiran Haresh Kumar Patel, Roshni Shetty, Haibo Ni, Eleonora Grandi, Fu Siong Ng, Paul G. A. Volders, Matthijs J. M. Cluitmans, Jason D. Bayer   +9 more
wiley   +1 more source

Detection of QT interval prolongation using Apple Watch electrocardiogram in children and adolescents with congenital long QT syndrome. [PDF]

Int J Cardiol Heart Vasc, 2023
Yee-Ming Li J, Kwok SY, Tsao S, Hoi-Yan Chung C, Hing-Sang Wong W, Cheung YF.   +5 more
europepmc   +1 more source

Effects of palonosetron on prolongation of corrected QT intervals may be less than reliable [PDF]

, 2014
Jeounghyuk Lee, Junyong In
openalex   +1 more source