Cancer treatment and drug-induced QT interval prolongation: A review
Consilium Medicum, 2022 Anticancer drugs can cause drug-induced prolongation of the QT interval. Prolongation of the QT interval is a known risk factor and an independent predictor of the development of life-threatening ventricular arrhythmias (polymorphic ventricular ...
Olga D. Ostroumova +2 more
doaj +1 more source
Ventricular arrhythmia in patients with prolonged QT interval during liver transplantation: two cases report [PDF]
Korean Journal of Anesthesiology, 2014 QT interval prolongation is associated with an increased risk of ventricular arrhythmia in various conditions. Cardiac electrophysiologic abnormalities including QT interval prolongation are well documented in patients with advanced liver cirrhosis.
Min-Soo Kim +3 more
doaj +1 more source
Torsade de pointes in liver transplantation recipient after induction of general anesthesia: a case report [PDF]
Korean Journal of Anesthesiology, 2014 Torsade de pointes (TdP) is an uncommon and specific form of polymorphic ventricular tachycardia, associated with a prolonged QT interval. Prolongation of the QT interval is the most widely recognized electrophysiological abnormality in patients with ...
Eun-Jin Chung +6 more
doaj +1 more source
A Common Genetic Variant Risk Score is Associated with Drug-Induced QT Prolongation and Torsade de Pointes Risk: A Pilot Study. [PDF]
, 2017 Background -Drug-induced QT interval prolongation, a risk factor for life-threatening ventricular arrhythmias, is a potential side effect of many marketed and withdrawn medications.
Behr, ER +11 more
core +2 more sources
QT prolongation in HIV-positive patients: Review articleKey points
Indian Heart Journal, 2019 Introduction: Antiretrovirals have immensely increased the average life expectancy of HIV-positive patients. However, the incidence of QT interval prolongation and other arrhythmias has also increased. Methods: Pubmed and Google Scholar were searched for
Jing Liu +5 more
doaj +1 more source
Trigger versus Substrate: Multi-Dimensional Modulation of QT-Prolongation Associated Arrhythmic Dynamics by a hERG Channel Activator [PDF]
, 2017 Background: Prolongation of the QT interval of the electrocardiogram (ECG), underlain by prolongation of the action potential duration (APD) at the cellular level, is linked to increased vulnerability to cardiac arrhythmia.
Antzelevitch +57 more
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Hepatology, EarlyView., 2022 Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
Вестник анестезиологии и реаниматологии, 2018 Prolongation of QT interval is a predictor of fatal disorders of cardiac rhythm and sudden death. Side effects of medications is one of the main causes of prolonged QT interval.
E. V. Shikh +3 more
doaj +1 more source
Development of a Risk Score for QT Prolongation in the Intensive Care Unit Using Time-Series Electrocardiogram Data and Electronic Medical Records [PDF]
Healthcare Informatics Research, 2021 Objectives Drug-induced QT prolongation can lead to life-threatening arrhythmia. In the intensive care unit (ICU), various drugs are administered concurrently, which can increase the risk of QT prolongation.
Tae Young Kim +4 more
doaj +1 more source
QT peak prolongation predicts cardiac death following stroke [PDF]
, 2015 Cardiac death has been linked in many populations to prolongation of the QT interval (QTe). However, basic science research suggested that the best estimate of the time point when repolarisation begins is near the T-wave peak.
Douglas, Denise +7 more
core +1 more source