Results 91 to 100 of about 1,229,479 (285)

Fine mapping and single nucleotide polymorphism effects estimation on pig chromosomes 1, 4, 7, 8, 17 and X

Genetics and Molecular Biology, 2013
Fine mapping of quantitative trait loci (QTL) from previous linkage studies was performed on pig chromosomes 1, 4, 7, 8, 17, and X which were known to harbor QTL.
André M. Hidalgo, Paulo S. Lopes, Débora M. Paixão, Fabyano F. Silva, John W.M. Bastiaansen, Samuel R. Paiva, Danielle A. Faria, Simone E.F. Guimarães   +7 more
doaj   +1 more source

A QTL for osteoporosis detected in an F2 population derived from White Leghorn chicken lines divergently selected for bone index [PDF]

, 2007
Osteoporosis, resulting from progressive loss of structural bone during the period of egg-laying in hens, is associated with an increased susceptibility to bone breakage.
Preisinger, R., Fleming, R H, Dunn, I. C., C. C. Whitehead, R. Preisinger, McCormack, H A, Morrice, D., Preisinger, R, Fleming, R. H., D. Morrice, R. H. Fleming, Burt, D. W., I. C. Dunn, Burt, D W, Dunn, I C, H. A. McCormack, McCormack, H. A., Whitehead, C. C., Morrice, D, Whitehead, C C, D. W. Burt   +20 more
core   +1 more source

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

British Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba, Mishael Ssesanga, Munir Pirmohamed   +2 more
wiley   +1 more source

A Multiparent Advanced Generation Inter-Cross to fine-map quantitative traits in Arabidopsis thaliana.

PLoS Genetics, 2009
Identifying natural allelic variation that underlies quantitative trait variation remains a fundamental problem in genetics. Most studies have employed either simple synthetic populations with restricted allelic variation or performed association mapping
Paula X Kover, William Valdar, Joseph Trakalo, Nora Scarcelli, Ian M Ehrenreich, Michael D Purugganan, Caroline Durrant, Richard Mott   +7 more
doaj   +1 more source

Gene and QTL detection in a three-way barley cross under selection by a mixed model with kinship information using SNPs [PDF]

, 2011
Quantitative trait locus (QTL) detection is commonly performed by analysis of designed segregating populations derived from two inbred parental lines, where absence of selection, mutation and genetic drift is assumed.
Casas, Ana M., Ramsay, L., Fred A. van Eeuwijk, Mónica Elía, Bhat, Prasanna R., Malosetti, Marcos, Molina-Cano, José-Luis, Eeuwijk, F.A., van, Martin P. Boer, Luke Ramsay, Molina-Cano, J.L., Elía, Mónica, Marian Moralejo, Ramsay, Luke, Boer, M., Eeuwijk, Fred A. van, Moralejo, Marian, Ramsay, Luke D., Ana M. Casas, Molina-Cano, José Luis, José-Luis Molina-Cano, Boer, Martin P., Moralejo, María Ángeles, Marcos Malosetti, Malosetti, M., Casas Cendoya, Ana María, Prasanna R. Bhat, Bhat, P., Casas, A., Elia, M., van Eeuwijk, Fred A.   +30 more
core   +1 more source

QTL Mapping on a Background of Variance Heterogeneity [PDF]

G3 Genes|Genomes|Genetics, 2018
Abstract Standard QTL mapping procedures seek to identify genetic loci affecting the phenotypic mean while assuming that all individuals have the same residual variance. But when the residual variance differs systematically between groups, perhaps due to a genetic or environmental factor, such standard procedures can falter: in ...
Robert W. Corty, William Valdar
openaire   +3 more sources

Genetic and Molecular Basis of Processing Traits and Genetic Improvement Progress in Major Fruit Crops

Future Postharvest and Food, EarlyView.
Processing quality in fruit crops is governed by complex genetic networks controlling texture, sweetness, color, browning, aroma, and nutritional quality. Advances in genomics, genomic selection, and genome editing enable the development of processing‐oriented cultivars with improved industrial performance, reduced postharvest losses, and enhanced ...
M. Ranjani, Kaviya Dharshini U, Shalini Gaur Rudra   +2 more
wiley   +1 more source

Mapping Prolificacy QTL in Maize and Teosinte [PDF]

Journal of Heredity, 2016
Teosinte, the ancestor of maize, possesses multiple ears at each node along its main stalk, whereas maize has only a single ear at each node. With its greater ear number, teosinte is referred to as being more prolific. The grassy tillers 1 (gt1) gene has been identified as a large-effect quantitative trait locus underlying this prolificacy difference ...
Liyan, Yang, Chin Jian, Yang, Qi, Cheng, Wei, Xue, John F, Doebley   +4 more
openaire   +2 more sources

Sorghum T2T pangenome highlights comprehensive genomic variation

iMetaOmics, EarlyView.
Three newly assembled telomere‐to‐telomere (T2T) genomes representing wild, landrace, and transformable germplasm were integrated with seven publicly available T2T genomes to construct a graph‐based pangenome. Comparative analyses revealed extensive centromere divergence, including distinct CEN137 monomer and CEN274 dimer organization, and showed that ...
Lihua Wang, Chuanzheng Wei, Hope O. Okunbor, Xiaofei Deng, Die Hu, Yongfei Wang, Junli Du, Ephrem Habyarimana, Yongfu Tao, Yi‐Hong Wang, Jieqin Li   +10 more
wiley   +1 more source

Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

Nature Communications, 2019
QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique ...
Alejandro Burga, Eyal Ben-David, Tzitziki Lemus Vergara, James Boocock, Leonid Kruglyak   +4 more
doaj   +1 more source